KEGG   Orcinus orca (killer whale): 101282448
Entry
101282448         CDS       T05247                                 
Symbol
ITGA2
Name
(RefSeq) integrin alpha-2
  KO
K06481  integrin alpha 2
Organism
oor  Orcinus orca (killer whale)
Pathway
oor03271  Virion - Rotavirus
oor04145  Phagosome
oor04151  PI3K-Akt signaling pathway
oor04510  Focal adhesion
oor04512  ECM-receptor interaction
oor04611  Platelet activation
oor04640  Hematopoietic cell lineage
oor04810  Regulation of actin cytoskeleton
oor04820  Cytoskeleton in muscle cells
oor05165  Human papillomavirus infection
oor05200  Pathways in cancer
oor05205  Proteoglycans in cancer
oor05222  Small cell lung cancer
oor05410  Hypertrophic cardiomyopathy
oor05412  Arrhythmogenic right ventricular cardiomyopathy
oor05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oor00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03271 Virion - Rotavirus
    101282448 (ITGA2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101282448 (ITGA2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    101282448 (ITGA2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    101282448 (ITGA2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101282448 (ITGA2)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    101282448 (ITGA2)
   04810 Regulation of actin cytoskeleton
    101282448 (ITGA2)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    101282448 (ITGA2)
   04611 Platelet activation
    101282448 (ITGA2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101282448 (ITGA2)
   05205 Proteoglycans in cancer
    101282448 (ITGA2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    101282448 (ITGA2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101282448 (ITGA2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101282448 (ITGA2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101282448 (ITGA2)
   05414 Dilated cardiomyopathy
    101282448 (ITGA2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oor04147]
    101282448 (ITGA2)
   04515 Cell adhesion molecules [BR:oor04515]
    101282448 (ITGA2)
   04090 CD molecules [BR:oor04090]
    101282448 (ITGA2)
Exosome [BR:oor04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   101282448 (ITGA2)
  Exosomal proteins of bladder cancer cells
   101282448 (ITGA2)
Cell adhesion molecules [BR:oor04515]
 Integrins
  Integrin alpha subunits
   101282448 (ITGA2)
CD molecules [BR:oor04090]
 Proteins
  101282448 (ITGA2)
SSDB
Motif
Pfam: VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_3 VWA_2 FG-GAP_3 FG-GAP_2 Integrin_alpha HisK_sensor ITGAX-like_Ig_3
Other DBs
NCBI-GeneID: 101282448
NCBI-ProteinID: XP_049563098
Position
3:complement(144826905..144932286)
AA seq 1179 aa
MRPGRTGGTLLRLVLVLNQGILNCCVAYNVGLPEAKIFSGPSSEQFGYAVQQFINPEGNW
LLVGSPWSGFPENRMGDVYKCPVDLSTTTCEKLNLQTSTSISNVTEMKTNMSLGLTLTRN
VGTGGFLTCGPLWAQQCGNQFYTTGLCSDVSPNFQLLTSFSPAVQTCPSLIDVVVVCDES
NSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANYPRVVFNLNTFKTKDEMIKATSQT
SQYGGDLTNTFKAIQYARDSAYSAAAGGRPGATKVMVVVTDGESHDGSMLKAVIDQCNND
NILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIF
SIEGTVQGGDNFQMEMSQVGFSADYSPQNDILMLGAVGAYDWSGTVVQQTPHGHLIFPKQ
AFDQILQDRNHSSYLGYSVASISTGKSVHFVAGAPRANYTGQIVLYSVNESGNITVIQSH
RGDQIGSYFGSVLCAVDVDKDTITDVLLVGAPMYMNDLKKEEGRVYLFTITKGVLNWHQF
LEGPEGVENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGREGTIRLRYSQ
KILGSDGAFSSHLQYFGRSLDGYGDLNGDSITDVSVGAFGQVIQLWSQSIADVSVVASFT
PEKITLLNKNAEINLKLCFSAKFRPAKQNNQVAIVYNITIDADQYSPRVTSRGLFKENNE
RCLQKTMIVNQAQSCSEYLIHIQEPSDVVSSLDLCVNISLENPGTNPALEAYSETVKVFS
IPFYKDCGDDGVCISDLVLDVQQLPAAQQQPFIVSNQNKRLTFSVALKNKKESAYNSGIV
VDFSENVFFASWSMPVDGTEVTCQIASSQKSVTCNVGYPALKREQQVTFTINFDFNLQNL
QNQASVSFQALSESYEENKADNSVNFKLSLLYDAEIHITRSTNINFYEVSSDGNIPSIVN
SFEDIGPKFIFFIKVTTGSVPVSMASVIIHIPQYTRGKNPLMYLTGVHTDQAGDISCKAE
INPLKIGQTSSSVSFKSENFRHVKELNCRTASCSNITCWLKDLQVKGEYFLNVSTRIWNG
TFAVSTFQTAQLTAAAEIDTYNPQIYAIEENTITIPITIMKPHEKAEVPTGVIVGSAIAG
ILLLLALVAVLWKLGFFKRKYEKMTKNPDEIDETTELNS
NT seq 3540 nt   +upstreamnt  +downstreamnt
atgcggccgggacggacaggcggcacactgctgcggctggtgttagtgctcaatcaaggc
attttaaattgctgtgtggcgtacaatgttggtctcccggaagcaaagatattttctggt
ccttcaagtgaacagtttggctatgcagtgcagcagttcataaatccagaaggcaactgg
ttactggttggttcaccatggagtggctttcctgagaaccgaatgggagatgtgtataaa
tgtcctgttgatctatccaccactacatgtgaaaaactgaatttgcaaacttccacgagc
atttccaacgttactgagatgaaaaccaacatgagccttggcttgacactgacaaggaac
gtgggaacgggaggatttctcacctgtggtcccctgtgggcacagcagtgcggaaatcag
ttttacacaaccgggttatgctctgatgtcagtcccaattttcagctcctgaccagcttt
tcacctgcagttcagacctgcccttccctcatagatgttgtggttgtatgtgatgaatca
aacagtatttacccctgggatgcagtaaagaactttttggaaaaatttgtgcaaggcctg
gatataggccccacaaagacacaggtgggcttaattcaatatgccaattatccaagagtg
gtgtttaacctgaacacttttaaaaccaaagatgaaatgattaaagcaacatcccagaca
tcccagtatggtggagacctcacaaatacattcaaagcaattcagtatgcaagagattct
gcttattcagcagctgctggtggacgaccaggtgctaccaaagtcatggtggttgtaact
gatggtgaatcccatgatggttcaatgttgaaagccgtaattgatcagtgtaacaatgac
aatatactgaggtttggcatagcagttcttgggtacttaaacagaaatgcccttgatact
aaaaatttaataaaagaaattaaagcaattgccagtattccaacagaaagatactttttc
aatgtttctgatgaagcagctctactagaaaaggctgggacattaggagaacaaattttc
agcattgaaggtactgttcaaggaggagacaacttccaaatggaaatgtcacaagtggga
ttcagcgcagattactctcctcaaaatgatattctgatgctgggtgcagtaggagcttat
gactggagtgggactgttgtccagcagacacctcatggacatttgatctttccgaaacaa
gcctttgaccaaattctgcaagacagaaatcacagttcatatttaggttactctgtggct
tcaatttctactggaaaaagtgtccacttcgttgctggagctcctcgggcaaattatacc
ggccagatagtgctgtacagtgttaatgagagtggcaacatcacagttattcagtctcac
agaggtgaccagattggctcctattttggtagtgtgctgtgtgcagtcgatgtggacaaa
gacaccattacagatgtgctcttggtaggtgcgccaatgtacatgaatgacctaaagaaa
gaggaaggaagagtctacctgtttactatcacaaagggcgttttgaattggcaccaattt
ctggaaggccccgagggtgttgaaaatgctcggtttggttcagcgattgcagctctttca
gacatcaatatggatggctttaatgatgtgatcgttggttcacctttggaaaatcagaac
tctggagctgtgtacatctacaatggtcgtgagggcaccattcgcctgaggtattcccag
aaaatcttggggtctgatggcgcctttagcagccacctccagtacttcgggagatccctg
gatggctatggagatttaaatggggattccatcactgatgtgtctgttggtgcctttgga
caggtcattcagctctggtcacagagtattgctgatgtatctgtagttgcttcattcaca
ccagaaaaaatcactttgctcaacaagaacgctgagataaaccttaaactctgtttcagc
gccaagtttagacctgctaagcaaaacaatcaagtggccattgtatataacatcacaatt
gatgcagaccaatattcacccagagtaacctccaggggattatttaaagaaaataatgaa
aggtgcttgcagaagaccatgatagtaaaccaagcacagagttgctctgagtacctcatc
cacatacaggagccctctgatgttgtcagctctctggatctgtgtgtgaacatcagtctg
gaaaaccctggcactaaccctgcccttgaagcctactctgagacagtcaaggtcttcagt
atccctttctataaagattgtggtgatgatggagtttgcatctctgatctagttctagat
gttcaacagctgccagcagctcaacaacagcccttcattgtcagcaaccaaaacaaaagg
ttaacattttcagtagcactgaaaaacaaaaaggaaagtgcatacaacagtgggattgtt
gttgatttttcagaaaatgtgttttttgcttcctggtccatgccggttgatgggacagaa
gtgacatgccagattgcttcatctcagaagtctgttacctgcaatgtgggctaccctgct
ttaaaaagggaacaacaggtgactttcactattaacttcgacttcaatcttcaaaacctt
cagaatcaggcctctgtcagtttccaagccttaagtgaaagctacgaggaaaacaaggca
gataattcagtcaacttcaaactctctctgctgtatgatgccgaaattcacataacaaga
tctaccaacataaatttttatgaagtctcctcggatgggaatattccttctattgtgaac
agttttgaagatattggtccaaaattcatcttcttcattaaggtaacaacaggaagtgtt
ccagtcagcatggcatctgtaatcatccatatccctcaatacaccagaggcaagaacccg
ctgatgtacctgactggggtgcacacggaccaggctggtgacatcagttgcaaagccgaa
ataaatccactgaaaataggacagacatcttcttctgtatctttcaagagtgaaaatttc
cgtcatgtaaaagaactgaactgcagaaccgcttcatgtagtaacatcacctgctggctg
aaagaccttcaggtgaaaggagaatacttccttaatgtgtctaccagaatctggaacggg
actttcgcagtatcgacatttcagacagcacagctgacggcagcagcagaaatcgacacc
tataaccctcagatatatgcgatcgaagaaaacaccatcacgattcccattaccataatg
aaaccccacgagaaagctgaagtaccaaccggagttatagtaggaagtgcaattgctgga
atccttttgttattagctctggttgcagttttatggaagcttggattcttcaaaagaaaa
tatgaaaaaatgaccaaaaatccagatgaaattgatgagaccacagaactcaacagctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (38)   

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