KEGG   Orcinus orca (killer whale): 101288152
Entry
101288152         CDS       T05247                                 
Symbol
ERBB3
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3 isoform X1
  KO
K05084  receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor01521  EGFR tyrosine kinase inhibitor resistance
oor04010  MAPK signaling pathway
oor04012  ErbB signaling pathway
oor04020  Calcium signaling pathway
oor04151  PI3K-Akt signaling pathway
oor05205  Proteoglycans in cancer
oor05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101288152 (ERBB3)
   04012 ErbB signaling pathway
    101288152 (ERBB3)
   04020 Calcium signaling pathway
    101288152 (ERBB3)
   04151 PI3K-Akt signaling pathway
    101288152 (ERBB3)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    101288152 (ERBB3)
   05205 Proteoglycans in cancer
    101288152 (ERBB3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101288152 (ERBB3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oor01001]
    101288152 (ERBB3)
Enzymes [BR:oor01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101288152 (ERBB3)
Protein kinases [BR:oor01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   101288152 (ERBB3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Furin-like Pkinase TM_ErbB1 Kinase-like
Other DBs
NCBI-GeneID: 101288152
NCBI-ProteinID: XP_004274222
Position
11:44392417..44409931
AA seq 1338 aa
MRANGALQVLGFLLSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTVDWRDIVRDREAEIVVKDNG
RTCPPCHEVCKGRCWGPGPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKICEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNVTSLGLRSLKEISAGRIYISANRQLCYHHSLNWTRLLRGPSEE
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPSQCLSCRNYSRGGVCVTHCNFLNGEP
REFAHEAECFSCHPECQPMEGTTTCNGSGSDACAQCAHFRDGPHCVSSCPFGVLGAKGPI
YKYPDAQNECRPCHENCTQGCKGPELQDCLGQTLALISKTHLAMALTVVVGLAVIFLILG
STFLYWRGRRIQNKRAMRRYLERGESVEPLDPSEKANKVSARIFKETELKKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPG
SSLQLITQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSETKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRESGPGIPPGAEPPALTNKELEEVELEPELDLDLELEAEEE
NLATTLGSALSLPLGTLTRPRGSQSLVSPSSGYMPMNQGNLGEAAQKSAVRGCSERCHRP
ASLHPVPRGRLASESSEGHVTGSEAELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTPV
TPQSPPGLEEEDVNGYVMPDAHLKGTSSREGTLSSVGLSSVLGTEEEDDDDEYEYMNRRR
KCSSSRPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLNPVPTMPNASTTPDEDYEYMN
RRRGGGGPGGDYAAMEACPAAEQGYEEMRAFQGPVHHGPQVHYARLKTLRSLEATDSAFD
NPDYWHSRLFPKANAQRT
NT seq 4017 nt   +upstreamnt  +downstreamnt
atgagagcgaacggggctctgcaggtgctgggcttcctcctcagcctggcccggggctcc
gaggtgggcaactcgcaggcagtgtgccctgggactctgaatgggctgagtgtgaccggc
gatgccgagaaccagtaccagacactgtacaagctctacgagaggtgtgaggtggtgatg
gggaacctggagatcgtgctcacaggacacaatgctgacctctccttcctgcagtggatc
cgagaagtgaccggctacgtccttgtggccatgaatgagttctctacgctgccactgccc
aacctccgagtggtgcgggggacccaggtctacgatgggaagtttgccatctttgtcatg
ttgaactacaacaccaactccagccatgctctgcgccagctccgctttactcagctcact
gagattctgtcagggggcgtttacattgagaagaatgataaactttgtcacatggacaca
gttgactggagggacatcgtgcgggaccgagaagccgagatagtggtgaaggacaatggc
aggacctgtcccccctgtcatgaggtctgcaaggggcgatgctggggtcctggaccagaa
gactgccagacactgaccaagaccatctgtgcccctcagtgtaatggtcactgctttggg
ccgaaccccaaccagtgctgccacgacgagtgtgcagggggctgctcgggccctcaggac
acagactgctttgcctgccggctcttcaatgacagtggagcctgtgtacgccagtgtcca
cagcctcttgtctacaacaagctaactttccagctggaacccaatccccacaccaagtat
cagtatggaggagtttgtgtagccagctgtccccataactttgtggtggatcaaacatct
tgtgtcagggcttgtcctcctgacaaaatggaagtagataaaaatggactcaagatatgt
gaaccttgtgggggtctgtgccccaaagcttgtgaggggacgggctctgggagccgcttc
cagactgtggactcgagcaacattgatggatttgtgaactgcaccaagatcctgggcaac
ctggactttcttatcaccggcctcaatggagacccctggcacaagattcctgctctggac
cctgagaagctcaatgtcttccggacagtgcgggagatcacaggttacctgaacatccag
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacgaccattgggggc
cgaagcctctacaaccggggcttctcactgttgatcatgaagaacttgaatgtaacatct
ctgggcctccgatccttgaaagaaattagtgctgggcgtatctacataagtgccaatcgg
cagctctgctaccaccattctttgaactggaccaggctgcttcgggggccttcggaagag
agactggacatcaagcataatcggccccgcagagactgcgtggcagaaggcaaagtgtgt
gacccactgtgctcctctgggggatgctggggcccaggccccagtcagtgcctatcttgc
cgaaactacagccgaggaggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagtttgcccatgaagctgaatgcttttcctgccacccggaatgccaacccatggag
ggcactaccacgtgcaatggctcgggctctgatgcttgtgcccagtgtgcccattttcga
gatgggccccactgtgtgagcagctgcccctttggagtcctcggtgccaagggccccatc
tacaagtacccagatgctcagaatgaatgtcggccctgtcatgagaactgcactcagggg
tgtaagggaccagagctacaagactgtttaggtcaaacactggcactgatcagcaaaacc
catctggcaatggctttaacagtggtagtaggattggcagtgattttcctgatcctgggc
agcacttttctctattggcgtgggcgccggattcagaataagagggctatgaggcgctac
ttggaacggggtgagagcgtagagcctctggaccccagtgagaaggctaacaaagtctcg
gccagaatcttcaaggaaacagagctgaagaagcttaaagtgctgggctcgggcgtcttc
ggaactgtgcacaaaggagtgtggattcctgagggtgaatcgatcaagattccagtctgc
attaaagtcattgaggacaagagtggacggcaaagttttcaagctgtgacggaccatatg
ctggccattggcagcctcgaccatgcccacattgtacggctgctgggactgtgcccaggg
tcatctctgcagctcatcactcagtacctgcctctgggctccctgctggatcatgtgaga
caacaccgtggggcactggggccacagctgctgctcaactggggagtacaaattgccaag
ggaatgtactaccttgaggaacatggtatggtgcacaggaacctggctgcccgaaatgtg
ctactgaaatcacctagtcaggttcaggtggcagattttggggttgctgacttgctgccc
cctgatgataagcagctactgcacagtgagaccaagactccaattaagtggatggccctc
gagagtatccactttgggaaatacacacaccagagtgacgtctggagctatggagtgaca
gtttgggagctgatgacctttggggcagagccctatgcagggctgcgactggctgaagta
ccagatctgctggagaagggggagcggttggcacagccccagatctgtaccattgacgtc
tacatggtcatggtcaagtgttggatgattgatgagaacattcgcccaacctttaaagaa
ctagccaatgagttcaccaggatggcccgagacccaccacggtacctggtcataaagaga
gagagtgggcctggaattccgcctggggcagagccccctgctctaacaaacaaggaactg
gaggaagtagagctggagccagaactagacctagacctggagttggaggcagaggaggag
aacttggcaaccacactaggctctgcccttagcctgccacttggaacacttactcggcca
cgtgggagccagagccttgtaagtccatcatcgggatatatgcctatgaaccaggggaat
cttggggaggctgcccagaagtctgcagttcgtgggtgtagtgaacgctgccaccgtcca
gcctctctgcacccagtgccacggggacgcctggcatcagagtcatcggagggccatgtg
acaggctctgaggccgagctccaggagaaggtatccatgtgtagaagccggagccggagc
ccacggccacgaggagacagtgcctaccattcccagcgccacagcctgcttactcctgtc
accccacagtccccaccagggttagaggaagaggatgtcaatggttatgtcatgccagat
gcacacctcaaaggtacctcctcccgggaaggcaccctttcttcagtgggtctcagttct
gtcctgggtactgaagaagaagatgacgacgacgagtatgaatacatgaaccggaggaga
aagtgcagttcatctcgtccccctaggccaagttcccttgaggagctgggttatgagtac
atggatgtgggatcagacctcagtgcttccctgggcagcacacagagttgcccactcaac
cccgtgcccaccatgcccaacgccagcacaactccggatgaagattatgaatatatgaat
cggcgacgtggtggaggaggtcctgggggggattatgcagccatggaggcctgcccagca
gctgagcaagggtatgaagaaatgagagctttccaggggcctgtacaccatggcccccag
gtccattatgcccgcctcaaaactctacgtagtttagaagccactgactctgcctttgat
aaccccgattactggcatagccggcttttccccaaggctaatgcccagagaacataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (54)   

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