KEGG   Orcinus orca (killer whale): 101288996
Entry
101288996         CDS       T05247                                 
Symbol
EIF2AK4
Name
(RefSeq) eIF-2-alpha kinase GCN2 isoform X1
  KO
K16196  eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04140  Autophagy - animal
oor05160  Hepatitis C
oor05162  Measles
oor05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:oor00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101288996 (EIF2AK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    101288996 (EIF2AK4)
   05162 Measles
    101288996 (EIF2AK4)
   05168 Herpes simplex virus 1 infection
    101288996 (EIF2AK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oor01001]
    101288996 (EIF2AK4)
Enzymes [BR:oor01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101288996 (EIF2AK4)
Protein kinases [BR:oor01001]
 Serine/threonine kinases: Other
  PEK family [OT]
   101288996 (EIF2AK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr RWD HGTP_anticodon2 tRNA-synt_His Kinase-like HGTP_anticodon ABC1
Other DBs
NCBI-GeneID: 101288996
NCBI-ProteinID: XP_049561466
Position
2:complement(117821744..117937431)
AA seq 1651 aa
MAGGRGAHGRGRDEPPESYPQRQDHELQALEAIYGSDFQDLRPDACGRVKEPPEINLVLY
PQGLTGEEVYVKVDLRVKCPPTYPDVVPEIALMNAKGLSNETVNLLKSRLEEVAKKHCGE
VMIFELAYHVQSFLCEHNKPPPKSFHEEMLERRAQEEQRRQLEAKRKEEEEQREILHEIQ
RRKEEIKEEKKRKEMAKQERLEIASLSNQDHTPRKDPGGHRTAAILHGGSPDFIGNGKHR
TNSSGRSRRERQYSVCSSEDSPGSCEILYFSMGSPDQLMVHKGKCIGSDEQLGKLVYNAL
ETATGGFVSLYEWVLQWQKKMGPFLTSQEKEKIDKCKKQIQGAETEFNSLVKLSHPNIVR
YFAMNLKEQDDSIVVDILVEHTNGVSLSSHLSHSGPVPGHQLRRYATQLLSGLDYLHSNS
VVHKVLSASNVLVDAEGTIKITDYSISKRLADICKEDVFEQTRVRFSDSALPYKTGKKGD
VWRLGLLLLSLSQGQECEEYPVTIPSDLPTDFQDFLKKCVCLDDKERWSPQQLLKHSFIN
PQPKIPLLEQSPEDSGGQDYVETVIPSNQLPSAAFFSETQRQFSRYFIEFEELQLLGKGA
FGAVIKVQNKLDGCCYAVKRIPINPASRHFRRIKGEVTLLSRLHHENIVRYYNAWIERHE
RPAGPATPPPDAGPQALDGRALPRLPIGDSDTDGPGSVEAAAPPPILSSSVEWSTSAERS
GSARFPAAGPDSSSDEDDDEEHDGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNG
KNSCHESEPPATTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYI
HEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFAADGKQDDTSGDHLIKSDPSGHL
TGMVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMCYHPMVTASERIFVLNQLRDPT
SPKFPEDFDDGEHTKQKSVISWLLNHDPAERPTATELLRSELLPPPQMEESELHEVLHRT
LANVGGKAYRTVMAQTFSQRISPAVDYTYDSDILKGSFSIRTAKIQQHVGETIIRIFKRH
GAVQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYC
IERVFRPRKLDRFHPKELLECAFDIVTSTTNSSLPTAEIIYTIYEIIQEFPALQERNYSI
YLNHTMLLKAILLHCGIPEDKLNQVYVILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLY
KFIEQKGELQDLTPTINSLIKQKTGVAQLVQYGLKDLEEVVGLLKKLGIKLQVLINLGLV
YKVQQHSGIIFQFVAFIRRRQRAISEILAAGGRYDLLIPLFRGPQALGPVPTAIGVSIAI
DKITAAVLNMEEPVTVSSCDLLVVSVGQMSMSRAINLTQKLWSAGITAEIMYDWSQSQEE
LQEYCRHHEITYVALVSDKEGNHVKVKSFEKERQTEKRVLESDLVDHVVQKLRTKVSDER
TIREASDNLAVQNLKGSFSNASGLFEIHGATVFPIVSVVAPEKLSASTRRRYETQVQTRL
QTSLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKL
VCDEIYNIKVEKKVSVLFLYSYRDDYYRILF
NT seq 4956 nt   +upstreamnt  +downstreamnt
atggctgggggccgtggggcccacgggcgtggccgggacgagccgccggagagctaccca
cagcgacaggaccacgagctgcaggccctggaggccatctacggctccgacttccaggac
ctgcggccggacgcgtgcggacgggtcaaagagcctcctgaaatcaatttagttctatac
cctcagggcttgactggtgaagaagtatatgtgaaagtggatttgagagtgaaatgccca
cccacctatccagatgtagtccctgaaatagcattaatgaatgccaaaggtctgtcaaat
gaaactgttaatttgttaaagtcccgcctagaagaagtggccaaaaaacattgtggcgag
gtgatgatatttgaactggcttaccatgtgcagtcattcctctgcgagcacaacaagccc
cctcccaagtcttttcatgaagaaatgctggaaaggcgggctcaggaggagcaacggagg
cagttagaggccaagcggaaagaggaagaggagcaacgtgaaatccttcatgagattcag
agaaggaaagaagagataaaagaagagaaaaaaaggaaagaaatggctaagcaggaacgt
ttagaaatagctagtttgtcaaaccaagatcatacccctaggaaagacccaggaggacac
agaacagctgccattctgcatggaggctctcctgactttataggaaatggtaaacatcgg
accaactcatctggaaggtctaggcgagaacgtcagtattctgtgtgtagtagtgaagat
tctcctggctcttgtgaaatcctgtatttctctatgggtagtcctgatcagctcatggtg
cacaaagggaaatgtattggcagtgatgagcagcttggaaaattagtttacaatgctttg
gaaacagccactggcggctttgtctcgttgtatgagtgggttcttcaatggcagaaaaaa
atgggtccattccttaccagtcaagaaaaagagaagattgataagtgtaaaaagcagatt
caaggggcagaaacggaattcaactcactggtaaaattgagccatccaaacatagttcgc
tactttgcaatgaatctcaaagagcaagacgattccattgtggtggacattttagtggag
cacactaatggggtctccctctcgtcccacctaagccactcgggccctgtccccgggcat
cagcttcgcaggtacgcgactcagctcttgtcaggccttgattatttgcacagcaattcc
gtggtgcacaaggttctgagtgcatcgaatgtcttagtggatgcagagggcaccatcaag
attacagactacagcatttctaagcgcctagcggacatttgcaaggaggacgtgtttgag
caaacgcgggttcgttttagtgacagtgccctaccttataaaacggggaagaaaggggat
gtttggcgtcttggccttctgctgctctccctcagccaaggacaggagtgtgaagagtac
cctgtgaccatccctagtgacttaccaactgactttcaagattttctaaagaagtgtgtc
tgcttagatgacaaggaaagatggagtcctcagcagttgttaaaacacagctttataaat
cctcagccaaaaatacctttactggaacaaagtcccgaagattctggaggacaagattac
gtggagactgttattcccagcaaccagctacccagtgctgcgttcttcagtgagacacag
agacaattttcccgctacttcattgagtttgaagaattacagcttcttggcaaaggagct
tttggagctgtcatcaaggtgcagaacaagctggacggctgctgctacgcggtgaagcgc
atccccatcaacccggccagcaggcacttccgcaggatcaagggcgaggtgacgctgctg
tcgcgcctgcaccacgagaacatcgtgcgctactacaacgcctggatcgagaggcacgag
cggccggcgggccccgcgacgccgcccccagacgcggggccccaggccctggatgggcga
gccttgccccgactgcccatcggcgacagcgacacggacggcccgggcagcgtggaggcg
gccgcgccgccgcccatcctcagcagctcggtggagtggagcacatcggctgagcgctcg
ggcagcgcccgcttccccgccgccggcccggactccagcagcgacgaggatgacgacgag
gagcacgacggcgtcttctcacagtccttcctacctgcttcagattctgacagtgatatc
atctttgacaatgaagatgagaacagtaaaagtcagaatcaggatgaagattgcaatgga
aagaacagttgccatgaaagtgagccaccggcaaccactgaggctgtgcactacctctac
atccagatggagtactgtgaaaagagcactttacgtgacacaattgaccagggactatat
cgagacaccgtcaggctctggaggcttttccgagagattctggatggattggcttatatc
catgaaaaaggaatgattcaccgagatttgaagcctgtcaacatttttttggattctgat
gaccacgtaaaaataggtgattttggtttagcgacagaccatctagcctttgctgctgac
ggcaaacaagatgatacatcaggagatcacttgattaaatcagacccttcaggtcatttg
actgggatggttggcactgctttatatgtaagcccagaggtccaaggcagcaccaaatct
gcatataaccagaaagtggatctcttcagcctgggaattatcttctttgagatgtgctat
catcccatggtcacagcctcagaaaggatctttgttctcaaccaactcagagatcctact
tcgcctaagtttccagaagacttcgatgatggagagcacacaaagcagaaatctgtcatc
tcctggctgttgaaccacgatccggcagagcggcccacagccacagagctgctcaggagc
gaactgctgcctccgccccagatggaggagtcggagctgcacgaggtgctgcaccgcacc
ctggccaatgtgggcgggaaggcctaccgcacggttatggcccagaccttctcccagcgc
atctcccccgccgtcgattacacctacgacagcgacatactgaagggcagcttctccatc
cgtacagccaagatacagcaacacgtgggtgaaaccattatccgcatcttcaaaagacat
ggagctgtccaattgtgtaccccactgctgcttccccgaaataggcaaatatacgagcac
aatgaagctgccttattcatggaccacagcgggatgctggtgatgcttcctttcgacctg
cgggttccttttgcaagatacgtggcaagaaataatatcttgaatttaaaacggtactgc
atagaacgcgtgttcagacctcgcaaattagaccgatttcatcccaaagaacttctggaa
tgtgcgtttgatatcgtcacctctaccaccaacagctctctgcccaccgctgaaatcatc
tacaccatctatgaaatcatccaggagtttccagcacttcaggaaagaaactacagtatt
tacttgaaccataccatgttactgaaagcaatactcttacactgtgggatcccagaagat
aaactcaatcaagtctatgttattctgtatgatgctgtgaccgaaaagctgacgaggaga
gaagtggaagctaaattttgtaatctgtctttgtcatcgaatagtctgtgtcgactctac
aaatttattgagcagaagggagagctgcaagatctgacaccaacaataaattcattaata
aaacagaaaacgggtgttgcccagttggtgcagtatggcttaaaagatctagaagaggtt
gtgggactgttgaagaaacttggcataaagttacaggtcttgatcaatttgggcttggtt
tacaaagtgcaacagcacagcggaatcatcttccagtttgtggcgttcatcagacggagg
caaagggctatatctgaaatccttgcagctggtggcagatatgacctgctgattcccctg
tttagaggaccacaggctctggggccggttcctactgctattggggtcagcatagccata
gacaagataactgctgctgtcctcaacatggaagaacctgttacagtaagctcttgtgac
ctcctcgttgtaagtgttggccagatgtccatgtccagggccatcaacctaacccagaaa
ctctggtcagcgggaatcacagcagaaatcatgtatgactggtcacagtcccaagaggag
ttacaagaatactgcagacatcatgaaatcacctatgtggcccttgtctccgataaagaa
ggaaaccatgtcaaggttaagtcttttgagaaggaaaggcaaacagagaaacgtgtgctg
gagtctgatctcgtggaccatgttgtacagaaactgaggactaaagtcagtgatgaaagg
actatcagagaagcttccgataatcttgcagtacaaaatctgaaggggtcattttctaat
gcttcaggtttgtttgaaatccatggagcaacagtttttcccattgtgagcgtggtagcc
ccagagaagctgtcagccagcactaggaggcggtatgaaactcaggtacaaacccgactt
cagacctcccttgctaacttgcatcagaaaagcagtgaaattgagattttggctgtggat
ctacccaaagaaacaatcttacagtttctgtcattagagtgggatgctgatgaacaggca
tttaacacaactgtgaagcagctgctgtcacgcctgccaaaacaaagatacctcaaatta
gtctgtgatgaaatttataacatcaaagtagaaaaaaaggtgtctgtgctgttcctgtat
agctacagagatgactactacagaatcttattttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (8)   
   Pfam (8)   
All databases (51)   

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