KEGG   Odobenus rosmarus divergens (Pacific walrus): 101372249
Entry
101372249         CDS       T05148                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2
  KO
K02085  adenomatosis polyposis coli protein
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro04310  Wnt signaling pathway
oro04390  Hippo signaling pathway
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04810  Regulation of actin cytoskeleton
oro04934  Cushing syndrome
oro05010  Alzheimer disease
oro05022  Pathways of neurodegeneration - multiple diseases
oro05165  Human papillomavirus infection
oro05200  Pathways in cancer
oro05206  MicroRNAs in cancer
oro05210  Colorectal cancer
oro05213  Endometrial cancer
oro05217  Basal cell carcinoma
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
oro05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101372249 (APC2)
   04390 Hippo signaling pathway
    101372249 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101372249 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101372249 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101372249 (APC2)
   05206 MicroRNAs in cancer
    101372249 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101372249 (APC2)
   05225 Hepatocellular carcinoma
    101372249 (APC2)
   05226 Gastric cancer
    101372249 (APC2)
   05217 Basal cell carcinoma
    101372249 (APC2)
   05213 Endometrial cancer
    101372249 (APC2)
   05224 Breast cancer
    101372249 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101372249 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101372249 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    101372249 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101372249 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:oro01009]
    101372249 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:oro03036]
    101372249 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:oro04812]
    101372249 (APC2)
Protein phosphatases and associated proteins [BR:oro01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101372249 (APC2)
Chromosome and associated proteins [BR:oro03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centriole associated proteins
    101372249 (APC2)
Cytoskeleton proteins [BR:oro04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     101372249 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Arm Suppressor_APC Arm_APC_u3 APC_r SAMP bZIP_1 Sec7-like_HUS HALZ Wtap Sec2p CCDC138_cc
Other DBs
NCBI-GeneID: 101372249
NCBI-ProteinID: XP_004395465
UniProt: A0A2U3VKY2
Position
Unknown
AA seq 2267 aa
MASSVAPYEQLVRQVEALKAENSHLRQELQDNSSHLSKLETETSGMKEVLKHLQGKLEQE
AGVLVSLGQTEVLEQLKALQMDITSLYNLKFQPPALGPEPTARTPEESPVHGSGPSKDSF
GELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQM
DLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDQELLSAQDRVQQTEPQA
LLAVKSVSVDEDPEPEVPTHPEDGVPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSS
SPESCVAMRRSGCLPLLLQILHGAEAGAGGRNGSPGAPGAKDARMRANAALHNIVFSQPD
QGLARKEMRVLHVLEQIRAYCETCWDWLQARDSADGGGNGGAPVPIEPQICQATCAVMKL
SFDEEYRRAMNELGGLQAVADLLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVANK
ATLCARRGCMEAIVAQLASESEELHQVVSSILRNLSWRADINSKKVLREVGSMTALMQCV
LRASKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESGG
GILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSPRDQE
LLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKYQTTATAVSPGACAPSLYVR
KQRALEAELDTRHLAQALDHLEKQGLPEAEADTASKKPLPSLRHLDGLARDYASDSGCFD
DDEAPSLAAAAATAEPASPAVLSLFLGSPFLQGQALARAPPARRSGPEAEKEASGEVAVA
ARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRRPEG
RRPEPGSRAHPLLRLKAAHTSLSNDSLNSCSTGDGRCPREHTRPCPLAVLAEHREGPPCS
QVRPSRLDLHLPGSQEPASRDSSAADARVRTIKLSPTYQHVPLFESHPRAGMGPLAPGAR
KQAWLPTDGLSKVPEKLVADTVPLCLSRCSSLSSLSSAGRPGPSEAGDLDSDSSLEGLEE
AGPSKADLDGAWLGPGAASLPVAIPAPQRGRGLGVEDTTPSSSSENCVQETPLVLSRCSS
VSSLSSFESPSIASSVPSDPCSGLGSGTVSPSELPDSPGQTMPPSRSKTPPLVPVPPGER
ESTQFSLQWESYVKRFLDIADRRERCRLPSELDAGSVRFTVEKPDENFSCASSLSALALH
EHYVQKDVELRLLPPACPERGGGGGGPGLHFAGHRRRDEAGGCLEGPAAADQELELLREC
LGAAVPARLRKVASALVPGRRALPVPVYMLVPAPARVEDSCTDSAEGTPVTFSSATSLSD
ETLQGPPRDPPGGHSDRQKPAGREAPASQATGYRHRARGAGRSTEQARGAGRSRVGLELP
LRGPSSAYTDRASPRPSPARGDGALQSLCLTTPTEEAVYCFYDSDEEPSKAVVPPRRASA
IPRAVKREHQTGRKEVQAVPKATPKATQAARAQPSLIADETPPCYSLSSSASSLSEPDPP
EPPAPPASRPHAPQPAANKVPGTGGVRNGPLSPRAETGLLRRCVGSAVPRRRLQASGPRR
RKPQAAQPDKRPAEAPRERGDEAASSDHASDLDSVEWRAIQEGANSIVTWLHQAAAAATH
EASSGSDSILSGSGLSGSSTLQPPLHRKGQRLQAGSQAVSTARPEKRNSALAQHSTSGPE
KLRGAQKTACRVPAVLRGRTVIYVPSPAPRAQPRGNAGTRVAPRKMGPLSPAQPAAPAKT
PSPGQQRSRSLHRPGKISELAALRPPQRSATPPARLAKAPSSGSSPASPASQPPTRRLPP
GAQAAGPLPGPGASLVPQTPTRALLSKQHKTQKSPVRIPFMQRPARRGPPPLARAAPEPG
PRGRAAAEGSPGARGGRLGLVRMASARSSGSESSDRSGFRRQLTFIKESPGLLRRRRSEL
SAPEAAPPASQGGSPHRTRPALPAVFLCSSRCDELRAAPRQVPVPQRAPVARPSPSERPA
RRPSSESPSRLPVRTPATRPETVKRYASLPHISVARRPDTAAPGSTTDAARRSSDGEARP
LPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLMGAPSEEGPSGPPQRKTSDAVVQTED
FAATKTNSSTSPSLESRGPPQAPVSGPTALSGSDVDGPGPTKAPTSAPFVHEGLGVAAGG
FPASRHGSPSRSARVSPFNYVPSPMVAATTDLAAEKAPTAAPTSLLE
NT seq 6804 nt   +upstreamnt  +downstreamnt
atggcgagctctgtggcaccctacgagcagctggtgcggcaggtggaggccttgaaggcc
gagaacagtcacctgaggcaggagctgcaggacaattccagccacctgtccaagctagag
acggagacatccggcatgaaggaggtcctgaagcacttacaaggcaagctggaacaggag
gctggagtgctggtgtctttggggcagaccgaggtcctggagcagctgaaagccctgcag
atggacatcaccagcctgtacaacctcaagttccagcccccagccctaggccccgagccc
actgcgcggacccccgaagaaagtcccgtccacggctctgggccctctaaggacagcttt
ggggagctgagccgggctaccatccggctgctggaggaactggaccgggaacggtgcttt
ctgttgaacgagatcgagaaggaggagaaggagaagctctggtattactcacagctgcag
ggcctgtccaagcgcctggacgagctcccgcacgtggagacgcagttctcgatgcagatg
gacctgatccggcagcagctggagttcgaggcccagcacatccgctcgctgatggaggag
cgcttcggcacctcggacgagatggtgcagcgggcgcagatccgcgcttcgcgcctggag
caaattgatcaggaactgctgtccgcgcaggaccgcgtgcaacagaccgagccccaggcc
ctgctggcggtgaagtcagtgtcggtggacgaggacccagagcctgaggtccccacgcac
cctgaggatggtgtccctcagccgggcaacagcaaggtggaggtggtcttctggctgctg
tccatgctggcgacgcgtgaccaggaggacacggcccgcaccctgctggcgatgtccagc
tcgccagagagctgcgtggctatgcgccgctcggggtgcctgccgctgctgctgcagatc
ctgcacggcgccgaggctggcgccgggggtcggaacgggagccccggggcgccgggagcc
aaggatgcgcgcatgcgcgccaacgcggcgctgcataacattgtcttctcgcagccggac
cagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcagatccgggcctac
tgtgagacgtgctgggactggctgcaggccagggacagcgccgacggaggcggcaacggc
ggcgcccccgtccccattgagcctcagatctgccaggccacttgtgccgtgatgaagctg
tcctttgatgaggaataccgccgtgccatgaacgagctgggtgggctgcaggccgtagcg
gacttgctgcaggttgactacgagatgcacaagatgacgcgggacccgctcaacctcgcc
ctacgccgatacgctggcatgaccctcaccaacctcacctttggggatgtcgccaacaag
gccacgctgtgtgcccgccggggctgcatggaggccattgtggcccagctggcttccgag
agcgaggagctccaccaggtggtgtccagcatcctgcgcaacctgtcctggcgggccgac
atcaacagcaagaaggtgctgagggaggtcggcagcatgactgctctgatgcagtgtgtt
ctgcgagcctccaaggagtccacactgaagagcgtgctcagtgccctgtggaacctgtca
gcacacagcactgagaacaaggcggccatctgccaggtggacggtgcgctgggcttcctg
gtgagcacgctgacctacaagtgccagagcaactctctggccatcatcgagagcggcggc
ggcatcctgcgcaacgtgtccagcctcatcgccacccgggaggactacagacaggtgctg
cgggaccacaactgcctgcagacgctgctccagcacctgacatcccacagcctgaccatc
gtaagcaacgcctgcggcacgctctggaacctgtccgcccgcagcccgcgcgaccaggag
ctgctgtgggacctgggggccgtgggcatgctgcgcaacctggtgcactccaagcacaag
atgatcgccatgggcagcgccgccgccctgcgcaacctgctggcgcaccggccggccaag
taccagaccacagccacggcggtctcccccggcgcgtgcgcgcccagcctgtacgtgcgg
aagcagcgggcgctggaggctgagctggacacgcggcacctggcgcaggcgctcgaccac
ctggagaagcagggcctgcccgaggccgaggccgacaccgcctccaagaagccgctgcca
tccctgcggcacctggacgggctggcccgggactatgcctcggactcgggctgctttgac
gacgatgaggcgccctccctggctgcggcagccgccaccgcggagcctgccagcccagcc
gtgctgtcgctcttcctggggagccccttcctgcaagggcaggcgctggcccgtgccccg
cctgcccgccgcagtggcccggaggcggagaaggaggccagcggggaggtggccgtggcg
gccagggccaaggccaagttggcgctggcagtggcgcggatcgaccggctggtggaggac
atctctgccctgcacacctcatctgacgacagcttcagcctcagctctggggaccccggg
caggaagcgccgcgcgaaggccgggcccagtcctgctccccttgccggcgacccgagggc
aggcggccggagcctggcagccgtgcccacccactactgcggctgaaggctgcccacacc
agcctctccaacgacagtctcaacagctgcagcaccggtgacgggcgctgtccccgcgag
cacacacggccctgcccactggcagtgctggccgagcaccgcgaggggcccccgtgcagc
caggtaaggcccagccggcttgacctccatctgccaggcagccaggagccggcatcccgg
gacagctctgccgccgacgcccgtgtgcgcaccatcaagctgtcgcccacctaccagcac
gtgccgctcttcgagagccaccccagggcgggcatggggcccctggcccccggagcccgg
aagcaggcctggctgcccacggacggcctgagcaaggtgccagagaagctggtagcagac
acagtgccgctctgcctgtcccgctgcagctccctgtcctcactgtcctcggctggccgc
ccaggccccagcgaggccggggacctggacagtgactcgtccctggaggggttggaggag
gcaggacccagcaaggcagacctggacggggcgtggctcgggcccggggctgcctccttg
cccgtggccatcccggcaccccagcggggtcggggcctgggggtcgaggacaccacgcca
tccagctcctcggagaactgcgtacaggagacgccgctggtgctgagccgctgcagctca
gtgagctccttgagcagtttcgagagcccatccatcgccagctctgtccccagtgacccg
tgcagtgggctgggcagcggcacggtcagccccagcgagctgcccgacagccccgggcag
accatgccacccagccgcagtaagacgcccccgctggtccccgtgccccccggtgagcgc
gagagcacccagttcagcttgcagtgggagagctacgtgaagcgcttcctggacatcgca
gaccgccgcgagcgctgccggcttccatccgagctggacgcgggcagcgtgcgcttcacc
gtggagaagcccgacgagaacttctcgtgtgcttccagcctcagcgcgctggccctgcac
gagcactatgtgcaaaaggacgtggagctgcggctgctgcccccggcctgccccgagcgt
ggcggtggcggtggcggccctggactgcactttgctgggcaccgccggcgggacgaggct
ggtggctgccttgaggggccggccgccgccgaccaggagctggagctgctgcgtgagtgc
ctgggggcggcggtgcccgcccggctccgcaaggtggcctcggccctggtgcccggccgc
cgtgcgctgcccgtgcccgtctacatgctggtgcctgcccccgcccgggtggaagactcc
tgcaccgactccgctgagggcacgcctgtcaccttctccagtgccacctcactcagtgat
gagacactgcagggacctcccagggacccgcctggtgggcattcggacaggcagaagccc
gcaggtcgtgaggccccagccagccaggccaccggctataggcacagggcacggggtgcg
ggccggagcacggagcaggcccggggggcaggcaggagccgggtggggctggagctgccc
ctccgcgggccctcgagcgcctacacggaccgggccagcccccgccccagccctgcacgc
ggggacggggcgctgcagtcactgtgcctcacgacgcccaccgaggaggctgtgtactgc
ttctacgactcagatgaggagccctccaaggcggtggtgcccccgcggcgggcgtcagcc
atcccccgtgcagtaaagagagagcaccagactggcaggaaggaggtgcaggccgtgccc
aaggccacgcccaaggccacacaagccgcccgcgcccagcccagcctcatcgccgacgag
acgccgccatgctactccctgagctcctctgccagctccctcagcgagcctgacccccct
gagcctccagcgcccccggccagccggccccatgctccccagccagcagccaataaggtg
ccaggcactgggggggtgcgtaacggccccctgagcccgcgggcggagacaggcctgctc
cggcgctgcgttggctccgcggtgcctaggcgccggctccaggcgtcaggcccacggcgc
cgcaagccccaggctgcccagccagacaagcggccagcagaggcgccccgggagcgcggg
gatgaggcggcgagctcagaccatgcctcagacctggacagtgtcgagtggcgtgccatc
caggagggcgccaactccattgtcacatggctgcaccaggcggcagcggcagccacccac
gaggcctcgtccgggtctgactcgatcctgtcaggatccgggctgtccgggagctccacc
ctgcagccccccctgcacaggaagggacagcggctgcaggcggggagccaggcagtcagc
accgcgaggccggagaaacggaactcggccctggcccagcacagcaccagtggccccgag
aagctgcgcggtgctcagaagaccgcatgcagggtgccagctgtgctccggggacggacc
gtgatttatgtgcccagcccggccccccgggcccagcccagaggcaacgctggcacccgc
gtggcaccaagaaagatgggacccctgagtcctgcgcagccagcagcccccgccaaaacc
cccagccccgggcagcagcggtctcgaagcctgcaccggccaggcaagatctcagagctg
gcggcgctgaggcctccccagaggagcgccacaccacccgcccgcctggccaaggccccc
tcatccggctcctccccggcctctccagcctcccagccccctacgaggaggctgccccca
ggcgcccaggccgcagggcccctccccggccccggggcatctctggtgccccaaacaccc
acacgggccctgctgtccaagcagcacaagacacagaagtcacctgtgcggatccccttc
atgcagaggccagccaggcgggggccaccacccctggccagggcagccccagagccaggg
ccccggggtcgggcggcagctgaaggaagccctggcgcccgagggggccgcctgggcctg
gtgcgcatggcctctgcccgctccagcggcagcgagtcctccgaccgctcgggtttccgg
cggcagctgacctttatcaaggagtccccgggcctgctgcgccgccgccgttcagaactg
tccgctcccgaggctgcgccccccgcctcccagggcggctcaccccaccgcactcgacct
gcgctgcccgccgtcttcctctgctcctcgcgctgcgacgagctgcgggcagccccccgg
caggttccggtcccccagcgagcccccgtggctaggcccagtcccagtgagcggccggcc
cggcgccccagctctgagagcccatcccgcctgcctgtccgcaccccggccacccggccc
gagacggtcaaacgctacgcctctctgccgcacatcagcgtggcccgcaggcccgacaca
gccgcccctgggtccaccacggacgctgcccgccgcagcagcgatggggaggcccggcca
ctgccaagggtggcggctccgggcaccacgtggcgtcgcatccgggacgaggacgttcca
catatcctgcggagcacgctgcccgccactgccctgccactgatgggtgccccatccgag
gagggccccagcggccccccacagcgcaagaccagcgatgccgtggtccagacggaggac
tttgctgccactaagaccaactccagcacgtctccgagcctggaaagcagggggcccccc
caggccccagttagcggccccactgccctctctggcagcgatgtggacgggcccggtccc
accaaggcgcccacctctgctccctttgtccatgagggcctgggggtggctgcagggggc
tttcctgccagccggcacggctccccaagccgctcggcccgtgtctcccccttcaactat
gtgcccagccccatggtggcagccaccactgacttggctgcagagaaagcccccaccgct
gcccccaccagcctcctggaatag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (123)   
   KEGG ORTHOLOGY (1)   
   RefGene (119)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (161)   

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