KEGG   Odobenus rosmarus divergens (Pacific walrus): 101386211
Entry
101386211         CDS       T05148                                 
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
  KO
K05087  insulin-like growth factor 1 receptor [EC:2.7.10.1]
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04014  Ras signaling pathway
oro04015  Rap1 signaling pathway
oro04066  HIF-1 signaling pathway
oro04068  FoxO signaling pathway
oro04114  Oocyte meiosis
oro04140  Autophagy - animal
oro04144  Endocytosis
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04152  AMPK signaling pathway
oro04211  Longevity regulating pathway
oro04213  Longevity regulating pathway - multiple species
oro04510  Focal adhesion
oro04520  Adherens junction
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04730  Long-term depression
oro04913  Ovarian steroidogenesis
oro04914  Progesterone-mediated oocyte maturation
oro05200  Pathways in cancer
oro05202  Transcriptional misregulation in cancer
oro05205  Proteoglycans in cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05218  Melanoma
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101386211 (IGF1R)
   04014 Ras signaling pathway
    101386211 (IGF1R)
   04015 Rap1 signaling pathway
    101386211 (IGF1R)
   04066 HIF-1 signaling pathway
    101386211 (IGF1R)
   04068 FoxO signaling pathway
    101386211 (IGF1R)
   04151 PI3K-Akt signaling pathway
    101386211 (IGF1R)
   04152 AMPK signaling pathway
    101386211 (IGF1R)
   04150 mTOR signaling pathway
    101386211 (IGF1R)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101386211 (IGF1R)
   04140 Autophagy - animal
    101386211 (IGF1R)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101386211 (IGF1R)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101386211 (IGF1R)
   04520 Adherens junction
    101386211 (IGF1R)
   04550 Signaling pathways regulating pluripotency of stem cells
    101386211 (IGF1R)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    101386211 (IGF1R)
   04914 Progesterone-mediated oocyte maturation
    101386211 (IGF1R)
  09156 Nervous system
   04730 Long-term depression
    101386211 (IGF1R)
  09149 Aging
   04211 Longevity regulating pathway
    101386211 (IGF1R)
   04213 Longevity regulating pathway - multiple species
    101386211 (IGF1R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101386211 (IGF1R)
   05202 Transcriptional misregulation in cancer
    101386211 (IGF1R)
   05205 Proteoglycans in cancer
    101386211 (IGF1R)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101386211 (IGF1R)
   05214 Glioma
    101386211 (IGF1R)
   05218 Melanoma
    101386211 (IGF1R)
   05215 Prostate cancer
    101386211 (IGF1R)
   05224 Breast cancer
    101386211 (IGF1R)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101386211 (IGF1R)
   01522 Endocrine resistance
    101386211 (IGF1R)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oro01001]
    101386211 (IGF1R)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:oro04090]
    101386211 (IGF1R)
Enzymes [BR:oro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101386211 (IGF1R)
Protein kinases [BR:oro01001]
 Receptor tyrosine kinases (RTK)
  INSR family [OT]
   101386211 (IGF1R)
CD molecules [BR:oro04090]
 Proteins
  101386211 (IGF1R)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like fn3 Kinase-like DUF4476
Other DBs
NCBI-GeneID: 101386211
NCBI-ProteinID: XP_012419631
Position
Unknown
AA seq 1304 aa
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNTTVADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPGMGRAGI
NT seq 3915 nt   +upstreamnt  +downstreamnt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgacatccgc
aacgactatcagcagctgaagcgtctggagaactgcacggtgatcgagggctacctccat
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggggacctcttc
ccgaacctcacagtcatccgcggctggaagctcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaagaatgccgacctctgttacctctccacggtggactggtccctgatc
ctggatgccgtgtccaataactacatcgtgggcaacaaacccccaaaggaatgcggggac
ctgtgtccggggacaatggaggagaagcccttgtgtgagaagacaaccatcaacaacgag
tacaactatcgttgctggactacaaaccgttgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcaccgagaacaacgagtgctgtcaccccgagtgtctgggcagctgcagt
gcgcccgacaacgacacggcctgcgtggcgtgcaggcattactactatgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgttgcgtggaccgcgac
ttctgcgccaacatacccagcgccgagagcagcgactccgaggggtttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcggggttcatccggaacggcagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaatatccgccgaggcaataacattgcctcagaactggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccatgccttggtctccttgtcc
ttcctaaaaaaccttcgccagatcttaggagaggagcagctagaagggaactactccttc
tatgtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagctgggaaaatgtactttgctttcaatcccaaattgtgcgtctccgagatttac
cgcatggaggaagtgacagggactaaggggcgccagagcaaaggggacataaacaccagg
aacaacggagagcgagcctcctgtgaaagtgacgtcctgcatttcacctctacaaccacg
tggaagaatcgcatcatcataacgtggcaccgttaccggccccctgactacagggacctc
atcagcttcactgtctactacaaggaagcaccttttaaaaatgtcacggagtatgatgga
caggatgcctgcggctccaacagctggaacatggtggatgtggacctccctcccaacaaa
gacgtcgagcctggcattctgctgcacggactgaagccctggacgcagtatgctgtgtat
gtcaaggcggtgaccctcaccatggtggagaacgaccacatccgtggggccaaaagtgaa
atcttgtacattcgcaccaatgcttcagtcccttccattcccctggacgttctttccgcg
tccaactcctcttctcagctcattgtgaagtggaacccgccctccctgcccaacggcaac
ctcagttactacatcgtgagatggcagcggcagcctcaggacagctacctttaccggcac
aactactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacgtg
gaagaggtgacggagaatcccaagaccgaggtgtgtggcggagagaaggggccttgttgc
gcctgccccaaaaccgaggccgagaagcaggccgagaaggaggaggccgagtaccgaaaa
gtcttcgagaactttctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gacgtcacacaagtcactaacaccaccatgtctagccgaagcaggaacaccacggtggca
gatacctataatatcacagacccagaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctctaacctccggccttttactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgg
gagtcgaggcctgaaaactccatctttctaaagtggccggaacctgagaatcccaacgga
ttgattctaatgtatgaaataaaatatggatcacagatcgaggatcagcgggaatgtgta
tcgagacaggagtacaggaagtatggaggcgccaagcttaaccggctcaaccccgggaac
tatacggcccggatccaggccacctctctctctgggaatgggtcctggacggatcctgtg
ttcttctacgtcccagccaaaataacgtatgaaaacttcatccatctgatcatcgctctg
cctgttgctgtcctgttgatagtgggagggctggttataatgttgtatgtcttccacagg
aaaagaaataacagcaggctggggaatggagtgctgtacgcttccgtgaacccagagtac
ttcagcgccgccgacgtgtacgtacctgacgagtgggaagttgctcgagagaagatcacc
atgagccgagagctggggcagggctcatttgggatggtatacgaaggagttgccaaaggc
gtggttaaagatgagcccgaaaccagggtggccattaaaacagtgaacgaggccgcgagc
atgcgtgaaaggattgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtagtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacacggggggatctcaaaagctatctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggggagattgca
gatggcatggcatacctcaacgccaacaagtttgtccacagagaccttgctgcccggaac
tgcatggtggccgaagatttcacagtcaaaatcggagattttggtatgacgagagacatc
tacgagacagactattaccggaaaggaggaaaggggttgctgcctgtgcgctggatgtcc
cccgagtctctcaaggatggagtcttcactactcactccgacgtctggtccttcggcgtc
gtgctctgggagatcgccacgctggccgagcagccctaccagggcttgtccaacgagcag
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgccctgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagcccgaggagctggacctggagccaggcatgggg
cgagctggtatctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (29)   
   KEGG PATHWAY (29)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (55)   

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