KEGG   Pseudomonas aeruginosa PAO1: PA3792
Entry
PA3792            CDS       T00035                                 
Symbol
leuA
Name
(RefSeq) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
pae  Pseudomonas aeruginosa PAO1
Pathway
pae00290  Valine, leucine and isoleucine biosynthesis
pae00620  Pyruvate metabolism
pae01100  Metabolic pathways
pae01110  Biosynthesis of secondary metabolites
pae01210  2-Oxocarboxylic acid metabolism
pae01230  Biosynthesis of amino acids
Module
pae_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:pae00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    PA3792 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    PA3792 (leuA)
Enzymes [BR:pae01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     PA3792 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-GeneID: 879941
NCBI-ProteinID: NP_252481
UniProt: Q9HXK5
Position
4250828..4252606
AA seq 592 aa
MPGQPATAWLSDASLHLVTAFAWPRRPRNRLQRISPMSMLKDPSQKYRPFSAINLPDRTW
PSKTITEVPIWCSSDLRDGNQSLIEPMDAAKKMRFFKTLVQVGLKQIEVAFPSASDTDFN
FVRELIEGNHIPDDVTIQVLTQAREDLITRTFESLRGAKKAIVHVYNATAPSFRRIVFNQ
DKQGVVDIATNAAKLIKKLAAEQPETQWSFQYSPEIFSSTELEFSVEVCNAVIDVWQPTP
DNKIILNLPATVECATPNVYADQIEWFGRHVDKRDSVIISLHTHNDRGTGVAATELGLMA
GADRVEGCLFGNGERTGNVDLVTLALNMYTQGLHPQLDFSDIDAVRKVVEECNQLPVHPR
HPYVGDLVHTAFSGSHQDAIRKGFAQQKEDAIWEVPYLPIDPADIGRDYEAVIRVNSQSG
KGGITFLLEQEYGISLPRRMQIEFSQVVQGETDRLGLEMTAQQIYSLLENEYLKATSPYV
LASHRLQEENGTSAVDLEVSFDGEKQHWRGIGKGPLEALVAALPVKAEIMDYHEHAIGAG
ANAKAAAYIEIRLEGQRPLHGIGIDENITTASFRALFSALNRAVTQAEAKAA
NT seq 1779 nt   +upstreamnt  +downstreamnt
gtgcctggtcagcccgcgactgcgtggctgagcgacgcttctcttcatctcgtcactgcg
ttcgcctggccccgccggcccaggaaccgactccaaaggattagccccatgagcatgttg
aaagacccttcgcagaaataccgcccattctcggccatcaatctgcccgaccgcacctgg
ccgtcgaagaccatcaccgaggtgccgatctggtgcagttccgacctgcgcgacggcaac
cagtcgctgatcgaaccgatggacgcggcgaagaagatgcgattcttcaagaccctggtg
caggtcggcctgaagcagatcgaagtggccttcccgtcggcttccgataccgacttcaac
ttcgtccgcgagttgatcgaaggcaaccacatcccggacgacgtcaccatccaggtgctg
acccaggcccgcgaagacctgatcacccgcaccttcgaatccctgcgcggggcgaagaag
gccatcgtccacgtctacaacgccaccgccccgtcgttccgccgcatcgtcttcaaccag
gacaagcagggcgtcgtggacatcgccaccaacgccgcgaaactgatcaagaagctggcc
gccgagcaaccggagacccagtggtcgttccagtactcgccggaaatcttcagctctacc
gagctggagttctcggtggaggtctgcaacgcggtgatcgacgtctggcaaccgaccccg
gacaacaagatcatcctcaacctgccggccaccgtggagtgcgccacgccgaacgtctac
gccgaccagatcgaatggttcggccgccacgtcgacaagcgtgacagcgtgatcatcagc
ctgcacacccacaacgaccgtggcaccggcgtggccgccaccgagctgggcctgatggcc
ggcgccgaccgcgtcgaaggttgcctgttcggcaacggcgagcgcaccggcaacgtcgac
ctggtgaccctggccttgaacatgtacacccagggcctgcatccgcaactggacttctcc
gacatcgacgcggtgcgcaaggtggtcgaagagtgcaaccagttgccggtccacccgcgc
catccatatgtcggcgacctggtccataccgctttctccggctcgcaccaggatgccatt
cgcaagggcttcgcccagcaaaaggaagacgcgatctgggaagtgccgtacctgccgatc
gatccggccgacatcggccgcgactacgaagcggtgatccgggtcaacagccagtccggc
aagggcggcatcaccttcctgctcgaacaggagtacggcatcagcctgccgcggcgcatg
cagatcgagttcagccaggtagtgcaaggcgagaccgaccgtctcggcctggaaatgacc
gcacaacagatctactcgctgctggaaaacgaatacctcaaggcgacctcgccctacgtc
ctcgccagccatcgcctgcaggaagagaacggcaccagcgccgtcgacctggaagtctcc
ttcgacggcgagaagcagcactggcgcgggatcggcaagggaccgctggaagccttggtg
gccgccctgccggtcaaggcggaaatcatggactaccatgagcacgccatcggcgccggc
gccaatgccaaggccgcggcctatatcgagatccgcctggagggccagcgcccgctgcac
ggcatcggcatcgacgagaacatcaccaccgccagcttccgcgccctgttcagcgcgctg
aaccgcgcggtgacccaggccgaggccaaggcggcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (55)   

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