KEGG   Pseudomonas aeruginosa PAO1: PA4226
Entry
PA4226            CDS       T00035                                 
Symbol
pchE
Name
(RefSeq) dihydroaeruginoic acid synthetase
  KO
K12239  L-cysteine---[L-cysteinyl-carrier protein] ligase PchE [EC:6.2.1.69]
Organism
pae  Pseudomonas aeruginosa PAO1
Pathway
pae01053  Biosynthesis of siderophore group nonribosomal peptides
Brite
KEGG Orthology (KO) [BR:pae00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01053 Biosynthesis of siderophore group nonribosomal peptides
    PA4226 (pchE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:pae01008]
    PA4226 (pchE)
Enzymes [BR:pae01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.69  L-cysteine---[L-cysteinyl-carrier protein] ligase
     PA4226 (pchE)
Polyketide biosynthesis proteins [BR:pae01008]
 Nonribosomal peptide synthetase (NRPS)
  Nonlinear NRPS
   Pyochelin synthetase
    PA4226 (pchE)
SSDB
Motif
Pfam: AMP-binding Condensation PP-binding Methyltransf_12 Methyltransf_11 Methyltransf_23
Other DBs
NCBI-GeneID: 880048
NCBI-ProteinID: NP_252916
UniProt: G3XCV2
Structure
Position
complement(4736795..4741111)
AA seq 1438 aa
MDLPPDSRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLDSIRLMYLQERLRARG
STLDFAQLAQRPCLGAWLDLLACADRLSAPATVALPTAQDRDQPFELSSVQQAYWLGRGA
GEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFD
LQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAAD
VESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPD
APALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWS
ESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAID
HAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLD
HQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQAR
RALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAG
VRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEED
DPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDA
LLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHA
VSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGG
ATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLA
RGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVE
AALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTR
EILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGL
LAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLW
LDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISF
AALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLA
DLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPL
NGNGKVDRRRLAESMTRALGECRHEPSAEEPLEAHEQALAECWEAVLKRPVRRREASFFS
LGGDSLLATRLLAGIRERFGVRLGMADFYRQPTLAGLARHLQVQTVEIEETQLEEGVL
NT seq 4317 nt   +upstreamnt  +downstreamnt
atggatctgccccccgattcccgtaccgccctgcgcgactggctgaccgagcagctcgcc
gacctgctcggcgaaccgcttgctgacgtgcgcgccctggcggacgacgacgacctgctg
ggctgcggcctcgactcgatccgcctgatgtacctgcaggaacgcctgcgcgcgcgtggc
tcgacgctggacttcgcccagttggcgcagcgcccctgcctgggggcctggctcgacctg
ctggcctgcgcggaccggctgtccgccccggcaacggtcgcgctgccgacggcgcaggat
cgcgatcagccgttcgagctgtcttccgtgcagcaggcctactggctgggacgtggcgcc
ggcgaggtgctgggcaacgtcagctgccatgcctttctggaattccgcacgcgggatgtc
gacccgcagcgcctggccgcggcggcggagtgcgtgcgtcaacgccacccgatgttgcgg
gcgcgcttcctcgacggtcgccagcagatccttccgacgccgccgctgtcctgcttcgac
ctgcaggactggcgcaccttacaggtggacgaggccgagcgcgactggcaggcgctgcgc
gactggcgcgcccatgaatgcctggcggtggagcgcggccaggtgttcctgctcgggctg
gtgcgcatgccgggcggcgaggatcgcctctggctgagtctcgacctgcttgccgccgat
gtcgaaagcctgcgcctgctgctggccgaactgggcgttgcctacctggcgccggagcgc
ctggcggagccgccggcgctgcatttcgccgactacctggcgcaccgtgcggcgcaacgc
gccgaggccgcggcgcgggcccgcgactactggctggaacgcctgccgcgcttgccggac
gcgccggccctgccgttggcctgcgcgccggaaagcatccgccagccgcgcacccggcgc
ctggcattccagctttccgccggcgagagccggcgcctggagcgtcttgccgcgcagcat
ggcgtgaccttgtccagcgtgttcggctgcgccttcgcgctggtcctggcgcgctggagc
gaaagcgcggaatttctcctcaacgtgccgttgttcgatcggcatgccgacgacccgcgt
atcggcgaggtgatcgccgacttcaccaccctgttgctgctggagtgccggatgcaggcc
ggggtgtccttcgccgaggcggtgaagagcttccagcgcaacctccacggagccatcgac
cacgccgcattccccgccctggaggtgctccgcgaggcgcgccggcagggccagccacgc
tcggcgccggtggtgttcgccagcaacctgggcgaggagggcttcgtcccggcggccttc
cgcgacgctttcggcgatctccacgacatgctctcgcagaccccgcaggtctggctcgac
caccagctctaccgggtgggcgacggtatcctgctggcctgggatagcgtcgtcggcctg
ttccccgaaggtctgccggaaaccatgttcgaagcctacgtggggctgctccagcgtctc
tgcgacagcgcctgggggcagcccgccgatctgccgttgccctgggcgcagcaggcgcgc
cgggccctgctcaacggccagccggcatgcgccacggcgcgcaccctgcatcgcgacttc
ttccttcgcgccgccgaggcgccggatgccgacgcgctgctctatcgcgaccaacgtgtc
acccgcggcgaactggccgagcgtgcgctgcgcatcgccggcggcctgcgcgaagccggg
gtgcgccctggcgacgcggtcgaggtcagcctgccgcgcggaccgcagcaggtcgcggcg
gtattcggcgtgctcgccgcaggcgcctgctacgtgccgctggacatcgaccagccgccc
gcacggcggcgcctgatcgaagaggccgccggggtatgcctggcgatcaccgaggaggac
gatccgcaggccttgccgccgcgcctggatgtccagcgcctgctgcgcggcccggcgctg
gccgcccccgtgccgctggcgccgcaggcgagtgcctatgtgatctacacctcgggctcc
accggggtgcccaagggcgtcgaggtcagccacgcggcggcgatcaataccatcgacgcg
ctgctcgacctgctgcgggtgaacgcatcggatcgcttgctggcggtctccgcgctggac
ttcgatctgtcggtcttcgacctgttcggcggcctcggcgccggtgccagcctggtcctg
ccggcccaggaacaggcgcgcgatgccgctgcctgggcggaggctatccagcggcatgcg
gtgagcctgtggaactcggcgccggccttgctggagatggccctcagcctgccggcgagc
caggccgactatcgcagtctgcgggcggtgctgctgtccggcgactgggtggccctggac
ctgcccggccgcctgcgcccacgttgtgccgaaggctgccgcctgcatgtgctgggtggc
gctaccgaagcgggcatctggtcgaacctgcagagcgtcgatacggtgccgccgcactgg
cgttcgattccctacggccggccattgccgggacaggcctaccgggtggtcgacacccac
gggcgcgacgtgccggacctggtggtcggcgagctgtggatcggcggcgccagcctggcc
cgcggctatcgcaacgatcccgaactcagcgcccggcgtttcgtccacgatgcccagggc
cgctggtatcgcaccggcgatcgcggtcgctactggggcgacggtaccctggaattcctc
ggtcgggtcgaccagcaggtgaaagtgcgcggccagcgcatcgagttgggcgaggtggag
gccgcgctgtgcgcccaggctggcgtggagagcgcctgcgcggcggtgctcggcggtggc
gtggcgagcctcggcgcggtgctggtaccgcgcctggcgccacgggccgaaggctccatg
gatctaccggccgcacagcccttcgccggcctggcagaggccgaggcggtactcacccgg
gaaatcctcggcgcgctgctggaggcgccgctggagctagacgacggtttgcgccggcgc
tggctggactggctagcggactccgccgccagcgcgctgccgtcgctcgacgaggcgttg
cgccggctcggctggcaggccgcggggctgaccgcgatgggcaacgctctgcgcggcctg
ctcgccggcgaacaggcgccggccgcgctgctcctcgatccctggctggcgccgcaggcg
gtggccgcgcgcctgccggacggccgcgaggccctggcgcgcctgctcgaagcgctgccg
acgccggctgccggcgaacgcctgcgggtggcggtgctggatacccgcgccgggctctgg
ctcgaccagggcatggcctcgctgttgcgcccagggctggaactgaccctcttcgaacgc
agccgcgtcctcctcgacgccgccgccacccgcttgccggaacggatcgtggtgcaggcg
ctggacgacggcctgctacctgccgagcacctcggtcgctacgaccgggtgatcagcttc
gccgcgctgcacgcctacgaggccagccgcgaaggcctggcgctggcggcggcgctgctg
cgcccgcagggccgcctgttgctggtggacctgctatgcgagtcgccactggcgctgctc
ggtgcggccttgctcgacgaccggccgctgcgcctggcggagctgccgagcctgttggcc
gatctcgccgctgcgggactggcgccgcgttgcctgtggcgcagcgagcggatcgccctg
gtcgaggcgctggcaccgggactcgggctcgacgccgccgcgctccaggccggcctggag
caacgcctgccccaggcgatgcggcccgaacgcctgtggtgcctgccaagcctgccgttg
aacggcaatggcaaggtcgatcgtcgccgcctggccgagagcatgacccgcgcactcggc
gagtgtcgtcacgagccctcggcggaggagccgctggaagcccatgagcaagcgctggcc
gagtgctgggaagcggttctcaaacgcccggtgcgtcgtcgcgaggcgagcttcttcagc
ctcggcggcgacagcctgctggcgacccgcctgctggccggcatacgtgagcgtttcggc
gtacgcctgggcatggccgacttctatcgccagccgaccctggccggtcttgcccgccac
ttgcaggtgcagaccgtcgaaatcgaggaaacccaactggaagagggcgtgctatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (50)   

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