KEGG   Pseudomonas aeruginosa LES431: T223_17790
Entry
T223_17790        CDS       T02970                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
pael  Pseudomonas aeruginosa LES431
Pathway
pael00270  Cysteine and methionine metabolism
pael00450  Selenocompound metabolism
pael00670  One carbon pool by folate
pael01100  Metabolic pathways
pael01110  Biosynthesis of secondary metabolites
pael01230  Biosynthesis of amino acids
pael04980  Cobalamin transport and metabolism
Brite
KEGG Orthology (KO) [BR:pael00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    T223_17790 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    T223_17790 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    T223_17790 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    T223_17790 (metH)
Enzymes [BR:pael01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     T223_17790 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AHC66128
Position
3811714..3815418
AA seq 1234 aa
MSSPLTDRSARLQALQHALRERILILDGGMGTMIQSYKLEEADYRGERFADWPSDVKGNN
DLLLLSRPDVIQAIEKAYLDAGADILETNTFNATQVSQADYGMQSLAYELNVEGARLARQ
VADAKTAETPDKPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDELVENYVEATRGLIEG
GADLILIETIFDTLNAKAAIFAVQGVFEELGVELPIMISGTITDASGRTLSGQTTEAFWN
SVRHARPISVGLNCALGAKELRPYIEELSTKADTHVSAHPNAGLPNAFGEYDESPAEMAV
VVEEFAAAGFLNIVGGCCGTTPAHIEAIAKAVAKYPPRAIPEIPRACRLSGLEPFTIDRS
SLFVNVGERTNITGSAKFARLIREENYAEALEVAQQQVEAGAQVIDINMDEGMLDSKAAM
VTFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEAFKHHARLC
KRYGAAVVVMAFDEDGQADTQARKEEICKRSYDILVDEVGFPPEDIIFDANIFAIATGIE
EHNNYAVDFINACAYIRDHLPYALSSGGVSNVSFSFRGNNPVREAIHSVFLYYAIRNGLT
MGIVNAGQLEIYDEIPKALRDRVEDVVLNRTPEATEALLAIADDYKGGGAVKEAEDEEWR
SYSVEKRLEHALVKGITTWIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFL
PQVVKSARVMKQAVAHLIPFIEAEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNG
YDVVDLGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQNFQLPLMIGG
ATTSKAHTAVKIDPQYSNDAVVYVTDASRAVGVATSLLSKELKADYVARTRADYAVVRER
TANRSARTERLSYEQAIANKPAFDWAGYQAPTPSFTGVRVLDEIDLAVLAEYIDWTPFFI
SWDLAGKYPRILTDEVVGEAATSLFNDAQAMLKKLIDEKLIKARAVFGFWPANQVEHDDL
EVYGADGETLATLHHLRQQTIKPDGKPNLSLADFVAPKESGVRDYIGGFITTAGIGAEEV
AKAYEAKGDDYNSIMVKALADRLAEACAEWLHERVRKEYWGYARDEHLDNEALIKEQYVG
IRPAPGYPACPDHTEKGTLFELLDPQGLSGVSLTEHYAMFPAAAVSGWYFAHPQAQYFAV
GKIDKDQVERYSQRKGQEASVSERWLAPNLGYDD
NT seq 3705 nt   +upstreamnt  +downstreamnt
atgtccagcccgctcaccgatcgcagcgcccgcctgcaagccctccagcacgccctcagg
gaacgtatcctgatcctcgatggcggcatgggcaccatgatccagagctacaagctggaa
gaggccgactaccgcggcgagcgcttcgccgactggccgagcgacgtgaaaggcaacaac
gacctcttgctgctgagccgcccggacgtgatccaggccatcgagaaggcctacctcgac
gccggcgccgacatcctcgagaccaataccttcaacgccacccaggtgtcccaggccgac
tacggcatgcagtcgctggcctacgaactcaacgtcgaaggggcgcgcctggctcgccag
gtggcggacgcgaagaccgccgagaccccggacaagccgcgcttcgtcgccggcgtgctc
ggcccgaccagccgcacctgctcgatttccccggacgtgaacaaccccggctaccgcaac
gtcaccttcgacgaactggtggagaactacgtcgaggcgacccgcggcctgatcgaaggc
ggcgccgacctgatcctgatcgagaccatcttcgacaccctcaacgccaaggcggcgatc
ttcgccgtccagggcgtgttcgaggaactcggcgtggagctgccgatcatgatctccgga
accatcaccgacgcctccggccgcaccctgtcgggccagaccaccgaggccttctggaac
tcggtgcggcatgcccggccgatctcggtaggcctgaactgcgccctcggcgccaaggaa
ttgcggccgtacatcgaggaactgtcgaccaaggccgacactcatgtctcggcccacccc
aacgccggcctgccgaacgccttcggcgaatacgacgaatcgccggcggaaatggccgtg
gtggtcgaggaattcgccgccgccggcttcctcaatatcgtcggcggctgctgcggcacc
accccggcgcacatcgaggcgatcgccaaggcagtggccaagtacccgccgcgggccatc
ccggagattccccgggcctgtcgcctgtccggcctggagccgttcaccatcgaccgcagc
tcgctgttcgtcaacgtcggcgagcgcaccaacatcaccggttcggccaagttcgcccgg
ctgatccgcgaggaaaactacgcggaagctctcgaggtcgcccagcagcaggtggaagcc
ggcgcccaggtgatcgacatcaacatggacgaaggcatgctggactcgaaggcggccatg
gtcaccttcctcaacctgatcgcctccgagcccgacatctcgcgcgtgccgatcatgatc
gactcctccaagtgggaagtgatcgaggccggcctgaagtgcatccagggcaagggcatc
gtcaactcgatctcgatgaaggaaggcgtcgaggccttcaagcaccatgcccgcctgtgc
aagcgctacggcgccgcggtggtggtgatggccttcgacgaggacggccaggccgacacc
caggcgcgcaaggaagaaatctgcaagcgctcctacgacatcctggtcgacgaagtcggc
ttcccaccggaagacatcatcttcgatgcgaacatcttcgccatcgccaccggcatcgag
gaacacaacaactacgcggtcgatttcatcaacgcctgcgcctacatccgcgaccacctg
ccctacgccctgagctcgggcggggtgtccaacgtgtccttctcgttccgcggcaacaac
ccggtacgcgaggcgatccactcggtgttcctctactacgcgatccgcaacggcctgacc
atgggcatcgtcaacgccggccagctggaaatctacgacgagattccgaaagcgctgcgc
gaccgggtcgaggacgtggtgctcaaccgcacgcccgaggccaccgaggccctgctggcg
atcgccgacgactacaagggcggcggcgcggtcaaggaggccgaggacgaggaatggcgc
agctacagtgtcgagaagcgcctcgagcatgcgctggtcaagggcatcaccacctggatc
gtcgaggacaccgaggaatgccgccagcagtgtgcgcgtcccatcgaggtcatcgaaggt
ccgctgatgtccgggatgaacgtggtcggcgacctgttcggcgccggcaagatgttcctc
ccgcaggtggtcaagtccgcgcgagtgatgaagcaggcggtggcccacctgattcccttc
atcgaggcggagaaaggcgacaagccggaagccaagggcaagatcctgatggccacggtg
aagggcgacgtgcacgacatcggcaagaacatcgtcggcgtggtgctcggctgcaacggc
tatgacgtggtcgacctcggcgtgatggtgccggcggagaagatcctgcagaccgccatc
gccgagaaatgcgacatcatcggcctgtctggcctgatcacgccgtcgctggacgagatg
gtccacgtcgccaaggaaatgcagcggcagaatttccagttgccgctgatgatcggcggc
gccactacctcgaaggcgcataccgcggtgaagatcgatccgcagtacagcaacgacgcg
gtggtctacgtcaccgacgcctcgcgcgcggtaggcgtggccaccagcctgctgtccaag
gagctgaaggccgactacgtggcccgcacccgcgccgactacgcggtggtccgcgaacgc
acggccaaccgcagcgcccgcaccgagcggctgagctacgaacaggcgatcgccaacaag
ccggcgttcgactgggccggctaccaggcgccgacgccttccttcaccggcgtcagggtg
ctcgacgagatcgacctcgcggtgctcgccgagtacatcgactggacgccgttcttcatt
tcctgggacctggccggcaagtacccgcgcatcctcaccgacgaggtggtcggcgaggcc
gccacctcgttgttcaacgacgcccaggcgatgctgaagaagctgatcgacgagaagctg
atcaaggcccgcgcggtgttcggcttctggccggccaaccaggtcgagcacgacgacctg
gaggtctacggcgccgatggcgagaccctcgccaccctgcaccacctgcggcagcagacg
atcaagccggacggcaagccgaacctgtcgctggccgatttcgtcgcgccgaaggaaagc
ggcgtgcgcgactacatcggcggcttcatcaccaccgccgggatcggcgccgaggaagtg
gccaaggcgtacgaagccaagggcgacgactacaacagcatcatggtcaaggcgctcgcc
gaccgcctcgccgaagcctgcgccgagtggctgcacgagcgggtgcgcaaggagtactgg
ggctacgcccgcgacgaacacctcgacaacgaggccttgatcaaggagcaatacgtcggc
atccgcccggcaccgggctacccggcctgccccgaccataccgagaaaggcactctgttc
gaactgctcgatccgcagggcctgtccggcgtcagcctgaccgagcactacgcgatgttc
ccggccgcggcggtcagcggttggtatttcgcccacccgcaggcgcagtacttcgcggtc
ggcaagatcgacaaggaccaggtggaacgctacagccagcgcaagggccaggaagccagc
gtcagcgagcgctggctggcgccgaaccttggctacgatgactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (30)   

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