KEGG   Pseudomonas aeruginosa PAO1-VE13: N297_3230
Entry
N297_3230         CDS       T03097                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
paev  Pseudomonas aeruginosa PAO1-VE13
Pathway
paev00290  Valine, leucine and isoleucine biosynthesis
paev00660  C5-Branched dibasic acid metabolism
paev01100  Metabolic pathways
paev01110  Biosynthesis of secondary metabolites
paev01210  2-Oxocarboxylic acid metabolism
paev01230  Biosynthesis of amino acids
Module
paev_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:paev00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    N297_3230 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    N297_3230 (leuC)
Enzymes [BR:paev01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     N297_3230 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     N297_3230 (leuC)
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: AGY71829
Position
complement(3503287..3504711)
AA seq 474 aa
MAGKTLYDKLWDMHLVKQRDDGSALIYIDRHILHEVTSPQAFEGLRLAGRKPWRIDANIA
TPDHNVPTTRTERKGGIAAIADEVSRLQVQTLDENCDDFGITEFKMNDVRQGIVHVVGPE
QGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKNMLVKVEGRL
PAGVTAKDIVLAVIGRIGTAGGNGHAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGLVA
VDQKTIDYVKGRPFAPSAEQWDQAVACWQGLVSDADARFDTVVELDAAQIKPQVSWGTSP
EMVLAVDQNVPDPARESDPIKRGSIERALKYMGLRPNQAITDIQLDRVFIGSCTNSRIED
LRAAAEVARGRKVAATIKQALVVPGSGLVKEQAEKEGLDRIFIEAGFEWREPGCSMCLAM
NPDRLESGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVNGRFIDVRELLA
NT seq 1425 nt   +upstreamnt  +downstreamnt
atggccggcaagaccctctacgacaaactctgggacatgcacctggtcaagcagcgcgac
gacggttcggcgctgatctacatcgaccgccatatcctgcacgaagtgacctcgccgcag
gccttcgagggtcttcgcctggccgggcgcaagccgtggcggatcgacgccaacatcgcc
accccggaccacaacgtgccgaccacccgcaccgagcgcaagggcggcatcgccgccatc
gccgacgaggtctcgcgcctgcaggtgcagaccctcgacgagaactgcgacgacttcggc
atcaccgaattcaagatgaacgacgtgcgccagggcatcgtccatgtggtcggtccggag
cagggcgcgaccctcccggggatgaccgtggtctgcggcgactcgcacacttccacccac
ggcgccttcggcgcgctggcccacggcatcggcacttccgaggtagagcatgtgctggcg
acccagtgcctggtggcgaagaagatgaagaacatgctggtcaaggtcgaaggcaggctg
ccggccggcgtcacggcgaaggatatcgtcctcgcggtgatcggcaggatcggcaccgcc
ggcggcaacggccacgccatcgagttcgccggcagcgccatccgcgacctgtccatcgaa
gggcggatgaccatctgcaacatgtcgatcgaggcgggcgcccgcgtcggcctggtcgcc
gtcgaccagaagaccatcgactacgtgaagggccggcccttcgcgccgagcgccgagcaa
tgggaccaggccgtcgcctgctggcaggggctggtgtcggacgccgatgcccgcttcgat
accgtggtcgagctggacgccgcgcagatcaagccgcaggtcagctggggcacgtcgccg
gaaatggtcctggccgtggaccagaacgtgccggacccggcccgcgagagcgacccgatc
aagcgcggttcgatcgagcgcgccttgaagtacatgggcctgcggccgaaccaggcgatc
accgacatccagctggaccgggtattcatcggttcctgcaccaactcgcggatcgaggac
ctgcgcgctgccgccgaagttgccaggggccgcaaggtcgccgcgaccatcaagcaggcg
ctggtggtgccgggttccgggttggtcaaggagcaggccgagaaggaaggcctggaccgg
atcttcatcgaggccggcttcgaatggcgcgagccgggctgttccatgtgcctggcgatg
aacccggaccggctggagagcggcgaacactgcgcctcgacctccaaccgcaacttcgag
ggccgtcagggcgccggtggccgtacccacctggtcagcccggcgatggccgccgccgcg
gccgtcaacggccgcttcatcgatgtccgcgaattgctcgcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (1)   
   Pfam (1)   
All databases (47)   

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