KEGG   Pseudomonas aeruginosa LESB58: PLES_04241
Entry
PLES_04241        CDS       T00818                                 
Symbol
mexB
Name
(GenBank) Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB
  KO
K18138  multidrug efflux pump
Organism
pag  Pseudomonas aeruginosa LESB58
Pathway
pag01501  beta-Lactam resistance
pag01503  Cationic antimicrobial peptide (CAMP) resistance
Module
pag_M00718  Multidrug resistance, efflux pump MexAB-OprM
Brite
KEGG Orthology (KO) [BR:pag00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    PLES_04241 (mexB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    PLES_04241 (mexB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pag02000]
    PLES_04241 (mexB)
   01504 Antimicrobial resistance genes [BR:pag01504]
    PLES_04241 (mexB)
Transporters [BR:pag02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   PLES_04241 (mexB)
Antimicrobial resistance genes [BR:pag01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    PLES_04241 (mexB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF Patched
Other DBs
NCBI-ProteinID: CAW25151
Position
466932..470072
AA seq 1046 aa
MSKFFIDRPIFAWVIALVIMLAGGLSILSLPVNQYPAIAPPAIAVQVSYPGASAETVQDT
VVQVIEQQMNGIDNLRYISSESNSDGSMTITVTFEQGTDPDIAQVQVQNKLQLATPLLPQ
EVQRQGIRVTKAVKNFLMVVGVVSTDGSMTKEDLSNYIVSNIQDPLSRTKGVGDFQVFGS
QYSMRIWLDPAKLNSYQLTPGDVSSAIQAQNVQISSGQLGGLPAVKGQQLNATIIGKTRL
QTAEQFENILLKVNPDGSQVRLKDVADVGLGGQDYSINAQFNGSPASGIAIKLATGANAL
DTAKAIRQTIANLEPFMPQGMKVVYPYDTTPVVSASIHEVVKTLGEAILLVFLVMYLFLQ
NFRATLIPTIAVPVVLLGTFGVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
AEEGLSPREAARKSMGQIQGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMAL
SVIVALILTPALCATMLKPIEKGDHGEHKGGFFGWFNRMFLSTTHGYERGVASILKHRAP
YLLIYVVIVAGMIWMFTRIPTAFLPDEDQGVLFAQVQTPPGSSAERTQVVVDSMREYLLE
KESSSVSSVFTVTGFNFAGRGQSSGMAFIMLKPWEERPGGENSVFELAKRAQMHFFSFKD
AMVFAFAPPSVRELGNATGFDLFLQDQAGVGHEVLLQARNKFLMLAAQNPALQRVRPNGM
SDEPQYKLEIDDEKASALGVSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPDARM
NPDDLSKWYVRNDKGEMVPFNAFATGKWEYGSPKLERYNGVPAMEILGEPAPGLSSGDAM
AAVEEIVKQLPKGVGYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPFSV
MLVVPLGVIGALLATSMRGLSNDVFFQVGLLTTIGLSAKNAILIVEFAKELHEQGKGIVE
AAIEACRMRLRPIVMTSLAFILGVVPLAISTGAGSGSQHAIGTGVIGGMVTATVLAIFWV
PLFYVAVSTLFKDEASKQQASVEKGQ
NT seq 3141 nt   +upstreamnt  +downstreamnt
atgtcgaagtttttcattgataggcccattttcgcgtgggtgatcgccttggtgatcatg
ctcgcgggcggcctgtcgatcctcagtctgccggtcaaccagtacccggccatcgccccg
ccggccatcgccgtgcaggtgagctacccgggcgcctcggccgagacggtgcaggacacc
gtggtccaggtgatcgagcagcagatgaacgggatcgacaatctgcgctacatctcctcg
gagagtaactccgacggcagcatgaccatcaccgtgaccttcgaacagggcaccgacccc
gacatcgcccaggtccaggtgcagaacaagctgcaactggccaccccgctactgccgcag
gaagtgcagcgccaggggatccgggtgaccaaggcggtgaagaacttcctcatggtggtc
ggtgtggtttccaccgacggcagcatgaccaaggaagacctgtcgaactacatcgtttcc
aacatccaggacccgctctcgcggaccaagggcgtcggtgacttccaggtgttcggctcg
cagtactcgatgcgcatctggctcgacccggccaagctgaacagctaccagctgaccccc
ggcgacgtgagcagcgcgatccaggcgcagaacgtgcagatttcctccggccagctcggc
ggcttgccggcggtcaagggccagcagctcaacgccaccatcatcggcaagacccgcctg
cagaccgcggagcaattcgagaacatcctgctcaaggtcaatcccgacggttcccaggtg
cgcctgaaggacgtcgccgatgtaggcctgggcggccaggactacagcatcaacgcgcag
ttcaacggcagcccggcgtccggtatcgcgatcaagctggccaccggcgccaacgcgctg
gataccgccaaggcgatccgccagaccatcgccaacctggaaccgttcatgccgcagggc
atgaaggtggtctacccgtacgacaccaccccggtggtctcggcctcgatccatgaggta
gtgaagaccctcggcgaggcgatcctcctcgtgttcctggtgatgtacctgttcctgcag
aacttccgcgccacgctgatcccgaccatcgccgtaccggtggtgctgctggggaccttc
ggcgtgctcgccgcgttcggcttctcgatcaacaccctgaccatgttcggcatggtgctg
gccatcggcttgctggtggacgacgccatcgtggtggtggagaacgtcgagcgggtgatg
gccgaggaaggcctgtcgccaagggaggcggcgcgcaagtccatgggccagatccagggc
gcgctggtcggtatcgccatggtgctctcggcggtattcctgccgatggcgttcttcggc
ggctccaccggggtgatctaccggcagttctccatcaccatcgtgtcggccatggccctc
tcggtgatcgtggcgctgatcctcaccccggcgctctgcgcgaccatgctcaagccgatc
gagaaaggcgaccatggcgagcacaagggcggcttcttcggctggttcaaccggatgttc
ctttccaccacccacggctacgagcggggcgtggcgtcgatcctcaagcatcgcgcgccg
tacctgctgatctacgtggtgatcgtggccgggatgatctggatgttcacccgcattccc
accgcgttccttcccgacgaggaccagggcgtactgttcgcccaggtacagaccccgccg
ggctccagtgccgagcgtacccaggtggtggtggactcgatgcgcgaatacctgctggag
aaggaaagctcttcggtcagctcggtgttcaccgtgaccggcttcaacttcgccggccgc
ggccagagttcgggcatggcgttcatcatgctcaagccctgggaagagcgtcccggtggc
gagaacagcgtgttcgaactggccaagcgcgcgcagatgcacttcttcagcttcaaggac
gcgatggtgttcgccttcgcgccgccgtcggtacgggaactgggtaacgccaccggcttc
gacctgttcctccaggaccaggcgggtgtcggccacgaagtcctgctccaggcgcgcaac
aagttcctcatgctcgccgcgcagaacccggcgctgcaacgcgtgcgccccaacggcatg
agcgacgaaccgcagtacaagctggagatcgacgacgagaaggccagcgccctcggcgtg
tcccttgccgacatcaacagcaccgtgtccatcgcctggggttccagctacgtcaacgac
ttcatcgaccgtggccgggtcaagcgggtctacctgcagggcaggccggacgcgcggatg
aacccggacgacctgagcaagtggtacgtgcgcaacgacaagggcgagatggtgccgttc
aacgccttcgccaccggcaagtgggaatacggttcgccgaagctggagcgctacaatggc
gtgccggcgatggagatcctcggcgagccggcgcccggcctgagttccggtgacgccatg
gcggcggtcgaggagatcgtcaagcaattgccgaaaggcgttggctactcctggaccggc
ctgtcctacgaggagcgcttgtccggctcgcaggcgccggcgctgtatgcgctgtcgctg
ctggtggtgttcctctgcctggcggccctgtacgaaagctggtcgattccgttctcggtg
atgctggtggtgccgttgggcgtgatcggcgcgctgctggcgacgtccatgcgcggcctg
tccaacgacgtgttcttccaggtgggcctgttgacgaccatcggcctgtcggcgaagaac
gccattctcatcgtggagttcgccaaggagctgcacgagcagggcaagggcatcgtcgag
gcggccatcgaagcctgccgcatgcgtctgcggccgatcgtgatgacctccctggcgttc
atcctcggcgtggtcccgctggcgatctccaccggcgccggctcgggcagccagcatgcg
atcggtaccggcgtgatcggcggcatggtcactgcgaccgtcctggcgatcttctgggta
ccgctgttctacgtggcggtcagcacgctgttcaaggacgaggcgtccaagcagcaagcg
tccgtcgaaaaggggcaatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (13)   

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