KEGG   Pteropus alecto (black flying fox): 102886310
Entry
102886310         CDS       T02993                                 
Symbol
PLA2G4A
Name
(RefSeq) cytosolic phospholipase A2 isoform X1
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale00564  Glycerophospholipid metabolism
pale00565  Ether lipid metabolism
pale00590  Arachidonic acid metabolism
pale00591  Linoleic acid metabolism
pale00592  alpha-Linolenic acid metabolism
pale01100  Metabolic pathways
pale04010  MAPK signaling pathway
pale04014  Ras signaling pathway
pale04072  Phospholipase D signaling pathway
pale04217  Necroptosis
pale04270  Vascular smooth muscle contraction
pale04370  VEGF signaling pathway
pale04611  Platelet activation
pale04664  Fc epsilon RI signaling pathway
pale04666  Fc gamma R-mediated phagocytosis
pale04724  Glutamatergic synapse
pale04726  Serotonergic synapse
pale04730  Long-term depression
pale04750  Inflammatory mediator regulation of TRP channels
pale04912  GnRH signaling pathway
pale04913  Ovarian steroidogenesis
pale04921  Oxytocin signaling pathway
pale05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pale00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    102886310 (PLA2G4A)
   00565 Ether lipid metabolism
    102886310 (PLA2G4A)
   00590 Arachidonic acid metabolism
    102886310 (PLA2G4A)
   00591 Linoleic acid metabolism
    102886310 (PLA2G4A)
   00592 alpha-Linolenic acid metabolism
    102886310 (PLA2G4A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102886310 (PLA2G4A)
   04014 Ras signaling pathway
    102886310 (PLA2G4A)
   04370 VEGF signaling pathway
    102886310 (PLA2G4A)
   04072 Phospholipase D signaling pathway
    102886310 (PLA2G4A)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    102886310 (PLA2G4A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102886310 (PLA2G4A)
   04664 Fc epsilon RI signaling pathway
    102886310 (PLA2G4A)
   04666 Fc gamma R-mediated phagocytosis
    102886310 (PLA2G4A)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102886310 (PLA2G4A)
   04913 Ovarian steroidogenesis
    102886310 (PLA2G4A)
   04921 Oxytocin signaling pathway
    102886310 (PLA2G4A)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    102886310 (PLA2G4A)
  09156 Nervous system
   04724 Glutamatergic synapse
    102886310 (PLA2G4A)
   04726 Serotonergic synapse
    102886310 (PLA2G4A)
   04730 Long-term depression
    102886310 (PLA2G4A)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102886310 (PLA2G4A)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    102886310 (PLA2G4A)
Enzymes [BR:pale01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     102886310 (PLA2G4A)
SSDB
Motif
Pfam: PLA2_B C2 cPLA2_C2
Other DBs
NCBI-GeneID: 102886310
NCBI-ProteinID: XP_006907790
Position
Unknown
AA seq 749 aa
MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPISFMKVGEKKEV
PFIFNQVTEMILEMSLEVCSSPDLRFSMALCDQEKAFRYQRKENIKENMKKLLGPKNSEG
LCSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCTTYVAGLSGSTWYMSTLYSH
PDFPEKGPEEINEELMKNVSYNPLLLLTPQKVKRYVESLWKKKRSGQPVTFTDIFGMLIG
ETLIHNRMNITLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGKVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSSSQNKGSTMEEE
LENITAKHIVSNDSSDSDDESQEPKGTENEDAEREYQNDNQASWVHRMIMALMSDSALFN
TREGRAGKVHNFMLGLNLNTSYPLSPFRDFTTQDSLDEDELDAAVADPDEFEQIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN
KLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETT
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIIESIEYRR
QNPSRCSVSLSNIEARKFFNKESLSKPTA
NT seq 2250 nt   +upstreamnt  +downstreamnt
atgtcatttatagatccttatcagcacattatagtggagcatcagtattcccacaagttc
acagtagtggtgttacgtgccaccaaagtgacaaagggggccttcggtgacatgcttgac
actccagacccctacgtggaacttttcatctcctcaactcctgacagcaggaagagaaca
agacactttaataatgacataaaccccgtgtggaatgagacctttgaatttattttggac
ccaaatcaggaaaatgttttggagatcacgttaatggatgccaattatgtcatggatgaa
actctggggacagcaacatttcccatatcttttatgaaagtgggagagaagaaagaggtt
ccttttattttcaaccaagtcactgaaatgatcctggaaatgtcccttgaagtttgctca
tccccagacctccgatttagcatggctctgtgtgatcaggagaaagctttcagataccag
aggaaagaaaacataaaggagaacatgaagaaactcctgggtccaaagaacagtgaaggc
ttgtgttctacacgtgatgtacctgtggtcgccatactgggctcaggtggggggtttcga
gccatggtaggattctctggcgtgatgaaggcactgtatgaatcaggaattttggattgc
actacctatgttgctggtctttctggttccacatggtacatgtcaaccttatattctcac
cctgattttccagagaaagggccagaggagattaatgaagagctaatgaaaaatgttagc
tataacccccttttacttctcacaccacagaaagttaaaagatatgttgagtctttatgg
aagaagaaaaggtctggacaacctgtcacttttactgatatctttgggatgttaatagga
gaaacactaattcacaatagaatgaacattaccttgagtagtttgaaggaaaaagtcaat
acagcacaatgcccgttacctcttttcacctgtctgcatgtcaaacccgatgtttcagaa
ctgatgttcgcagattgggttgaatttagtccatatgagattggcatggctaaatatggt
acttttatggctcctgacttatttggaagcaaattttttatgggaaaagttgtgaagaaa
tacgaagaaaaccccttgcatttcttaatgggtgtctggggcagcgccttttctatattg
ttcaacagagtcttgggagtttccagttcacaaaataaaggttccaccatggaggaagaa
ttagaaaacattacggcaaagcatatcgtgagtaatgatagctcggatagtgatgatgaa
tcacaagaacccaaaggcactgaaaatgaagatgccgaaagggaatatcaaaatgataat
caagcaagttgggtccatcgtatgataatggccttgatgagtgattcagctctattcaat
accagggaaggacgtgctgggaaggttcacaacttcatgctgggcttgaatctcaataca
tcttatccactgtctcctttcagagacttcaccacacaggactccttagatgaagatgaa
ctggatgctgctgtagcagatcctgatgaatttgaacaaatatatgaacctctggatgtc
aaaagtaaaaagattcacgtagtagacagtggcctcacatttaacctaccttaccccttg
atcctgagacctcagaggggagttgatctcatcatctcctttgacttttctgcgaggcca
agtgactctagtcctccgttcaaggaacttctacttgcagaaaaatgggctaaaatgaac
aagcttccctttccaaagattgacccttatgtgtttgatcgagaaggactaaaggagtgt
tatgtctttaaacccaagaatcctgatgtagagaaagattgcccaactatcatccacttc
gttctggccaacatcaacttcagaaagtacaaggctccaggtgttccaagagaaactaca
gaagagaaagaaatagctgattttgatatttttgatgacccggaatcaccgttttcaacc
ttcaacttccaatatccaaatcaagcattcaaaaggcttcatgatctgatgtacttcaat
actctgaacaacatcgatgtgataaagaatgccatcattgaaagtatcgaatacagaagg
cagaatccatctcgttgttctgtttccctcagtaacattgaggcaagaaaatttttcaac
aaggagtctctaagcaaacccacagcataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (3)   
   Pfam (3)   
All databases (68)   

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