KEGG   Pteropus alecto (black flying fox): 102890575
Entry
102890575         CDS       T02993                                 

Gene name
ADCY4
Definition
(RefSeq) adenylate cyclase type 4
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale00230  Purine metabolism
pale01100  Metabolic pathways
pale01522  Endocrine resistance
pale04015  Rap1 signaling pathway
pale04020  Calcium signaling pathway
pale04022  cGMP-PKG signaling pathway
pale04024  cAMP signaling pathway
pale04062  Chemokine signaling pathway
pale04072  Phospholipase D signaling pathway
pale04114  Oocyte meiosis
pale04211  Longevity regulating pathway
pale04213  Longevity regulating pathway - multiple species
pale04261  Adrenergic signaling in cardiomyocytes
pale04270  Vascular smooth muscle contraction
pale04371  Apelin signaling pathway
pale04540  Gap junction
pale04611  Platelet activation
pale04713  Circadian entrainment
pale04714  Thermogenesis
pale04723  Retrograde endocannabinoid signaling
pale04724  Glutamatergic synapse
pale04725  Cholinergic synapse
pale04727  GABAergic synapse
pale04742  Taste transduction
pale04750  Inflammatory mediator regulation of TRP channels
pale04911  Insulin secretion
pale04912  GnRH signaling pathway
pale04913  Ovarian steroidogenesis
pale04914  Progesterone-mediated oocyte maturation
pale04915  Estrogen signaling pathway
pale04916  Melanogenesis
pale04918  Thyroid hormone synthesis
pale04921  Oxytocin signaling pathway
pale04923  Regulation of lipolysis in adipocytes
pale04925  Aldosterone synthesis and secretion
pale04926  Relaxin signaling pathway
pale04927  Cortisol synthesis and secretion
pale04928  Parathyroid hormone synthesis, secretion and action
pale04934  Cushing syndrome
pale04935  Growth hormone synthesis, secretion and action
pale04970  Salivary secretion
pale04971  Gastric acid secretion
pale04972  Pancreatic secretion
pale04976  Bile secretion
pale05032  Morphine addiction
pale05163  Human cytomegalovirus infection
pale05166  Human T-cell leukemia virus 1 infection
pale05200  Pathways in cancer
pale05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:pale00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102890575 (ADCY4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102890575 (ADCY4)
   04371 Apelin signaling pathway
    102890575 (ADCY4)
   04020 Calcium signaling pathway
    102890575 (ADCY4)
   04072 Phospholipase D signaling pathway
    102890575 (ADCY4)
   04024 cAMP signaling pathway
    102890575 (ADCY4)
   04022 cGMP-PKG signaling pathway
    102890575 (ADCY4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102890575 (ADCY4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102890575 (ADCY4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102890575 (ADCY4)
   04062 Chemokine signaling pathway
    102890575 (ADCY4)
  09152 Endocrine system
   04911 Insulin secretion
    102890575 (ADCY4)
   04923 Regulation of lipolysis in adipocytes
    102890575 (ADCY4)
   04912 GnRH signaling pathway
    102890575 (ADCY4)
   04913 Ovarian steroidogenesis
    102890575 (ADCY4)
   04915 Estrogen signaling pathway
    102890575 (ADCY4)
   04914 Progesterone-mediated oocyte maturation
    102890575 (ADCY4)
   04921 Oxytocin signaling pathway
    102890575 (ADCY4)
   04926 Relaxin signaling pathway
    102890575 (ADCY4)
   04935 Growth hormone synthesis, secretion and action
    102890575 (ADCY4)
   04918 Thyroid hormone synthesis
    102890575 (ADCY4)
   04928 Parathyroid hormone synthesis, secretion and action
    102890575 (ADCY4)
   04916 Melanogenesis
    102890575 (ADCY4)
   04925 Aldosterone synthesis and secretion
    102890575 (ADCY4)
   04927 Cortisol synthesis and secretion
    102890575 (ADCY4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102890575 (ADCY4)
   04270 Vascular smooth muscle contraction
    102890575 (ADCY4)
  09154 Digestive system
   04970 Salivary secretion
    102890575 (ADCY4)
   04971 Gastric acid secretion
    102890575 (ADCY4)
   04972 Pancreatic secretion
    102890575 (ADCY4)
   04976 Bile secretion
    102890575 (ADCY4)
  09156 Nervous system
   04724 Glutamatergic synapse
    102890575 (ADCY4)
   04727 GABAergic synapse
    102890575 (ADCY4)
   04725 Cholinergic synapse
    102890575 (ADCY4)
   04723 Retrograde endocannabinoid signaling
    102890575 (ADCY4)
  09157 Sensory system
   04742 Taste transduction
    102890575 (ADCY4)
   04750 Inflammatory mediator regulation of TRP channels
    102890575 (ADCY4)
  09149 Aging
   04211 Longevity regulating pathway
    102890575 (ADCY4)
   04213 Longevity regulating pathway - multiple species
    102890575 (ADCY4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102890575 (ADCY4)
   04714 Thermogenesis
    102890575 (ADCY4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102890575 (ADCY4)
  09165 Substance dependence
   05032 Morphine addiction
    102890575 (ADCY4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    102890575 (ADCY4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102890575 (ADCY4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102890575 (ADCY4)
   05163 Human cytomegalovirus infection
    102890575 (ADCY4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102890575 (ADCY4)
Enzymes [BR:pale01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     102890575 (ADCY4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N CD52
Other DBs
NCBI-GeneID: 102890575
NCBI-ProteinID: XP_006913595
Position
Unknown
AA seq 1077 aa
MPRLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLSALLALLAVAWASGRELASDRG
FLATVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV
SFFIFVIFTTYAMLPLGMRDAAALGLTSSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL
FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLGG
AYAVEDVAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR
YLESWGAAKPFAHLSHVESPVSTSTPLPEKALASFSPQWSLDRSRTPRRLDDELDTGDAK
FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFRYYAACTFLVFLSNFI
IQMLVTNRPPALAITYSITFLLFLLLLFACFSEHLTRCVLKGPKMLHWLPALSGLVATRP
GLRVALGTATILLVFSMAITSLFFLPAASNCPFRVPNVSSEAFNLSWELPGSLPLISIPY
SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLVARLYLGPLDS
RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETEMMENLTRL
LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR
LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAERSCSHLGTMV
EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST
GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRVGPPSATLG
NT seq 3234 nt   +upstreamnt  +downstreamnt
atgccccgcctcttcagtccccggccaccgcccagcgaagacctcttctatgagacctac
tacagtttgagccagcagtacccactgctgctactgctcctggtgatcgtgctctccgca
ctcctggcgttgcttgctgtcgcctgggccagtggcagggagctggcttcggacaggggc
ttcctggccacagtgctgtgcgcgctgggcgggttctcattgctgctgggcctggcttcc
cgcgagcagcgactgcagcgctggacgcgtcccctctccggccttgtgtgggcagcgtta
ctcgcgctaggccacggcttcctgttcactggaggcgtagtgagcgcctgggaccaggtg
tcctttttcatctttgtcatcttcaccacgtatgccatgctgcccttgggcatgcgggac
gccgccgccttgggcctcacttcatcactctcacacctgctggttctcgggctgtatctt
gggcctcagccagactcacgaccggcgctgctgcctcagttggcagcaaacgcggtgctg
ttcctgtgcgggaacgtggccggggcgtatcacaaagcgctgatggagcgggcgctgcgg
gccaccttcagagaggcgcttagttccctgcactctcgccggaggctggacacggagaag
aagcatcaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag
gcggagatcatggcaaggctgcaggctggacaggggtcacggccagagagcaccaacaac
ttccacagcctttatgtaaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg
ggcttcacacggctggccagtgaatgctccccaaaggagctggtgctcatgctcaacgag
ctctttggcaagttcgaccagattgccaaggagcatgaatgcatgcggatcaagatcctg
ggagactgttactactgtgtctctgggctgccgctctcactaccagaccacgccatcaac
tgtgtgcgcatggggctggacatgtgccgggccatcaggaaattgcgggcagccaccggt
gttgacatcaatatgcgcgtgggcgtgcactcgggcagcgtgctctgcggagtcatcggg
ctgcagaaatggcagtatgatgtctggtcccatgatgtcacactggccaaccacatggag
gcaggtggcgtgccaggacgagtgcatatcacaggggctaccctggccctgctaggagga
gcttacgctgtggaggatgtagccatggaacaccgggacccataccttcgagagctaggg
gagcctacctacctggtcatcgatccccgggccgaggaggaggatgagaagggcactgca
ggagggttgctgtcctctctcgaaggtcccaagatgcgtccatcactgctgatgacccgc
tatctggaatcctggggtgcagccaagccttttgcccatctgagccacgtagagagccct
gtgtccacctccacccctctgccggagaaagccctggcttccttcagcccccagtggagc
ctggaccggagccgtacccctcggagactagatgatgaactggacactggggatgccaag
ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcaaaggacttc
aacccactgacattgtacttccgagagaaggagatggaaaaagagtatcgactctccgca
ctccctgccttcagatactatgcagcctgcaccttcctggtttttctctccaacttcatc
atccagatgctggtgacaaacaggcccccggctctggccatcacctatagcatcaccttc
ctcctcttcctcctcctcctcttcgcctgcttctcagagcacctgacgaggtgtgttttg
aaaggccccaagatgctgcactggcttcccgcactgtctggcctggtggccacacgtccc
ggactgcgggttgccctgggcactgccaccatcctccttgtcttttccatggccattacc
agcctgttcttcttaccggcagcatcgaactgccctttccgggtgcccaatgtgtcctct
gaggctttcaacctctcctgggagctccctgggtccttgcctctcatcagcatcccatac
tccatgcactgctgtgtgctgggtttcctctcctgctccctctttctgcacatgagcttt
gaactgaagctgctgctgctcctgctgtggctggtggcctcctgctccctcttcctgcac
tcccatgcctggctgtcggattgcctcgttgcccgcctctatctcggccccttggactcc
aggccaggggtgctgaaggagcccaaactcatgggagctatctccttcttcatcttcttc
ttcacactccttgtcttggctcggcagaatgagtattattgccgcctggacttcctgtgg
aagaagaagctgaggcaggagcgggaagagacagagatgatggagaacctgactcggctg
ctcttggagaacgtgcttcctgcgcacgtggccccccagttcattggccagaaccggcgc
aacgaggacctctaccaccagtcctacgagtgtgtctgtgtcctcttcgcctcagtccca
gactttaaggagttttactccgaatctaacatcaaccatgaggggctagagtgtctgcgg
ctgctcaatgagatcattgctgattttgatgagctgctctctaagcccaagttcagtggg
gtggaaaagatcaaaacgatctgcagcacctacatggcagctacaggcttaaatgccacc
tctggacaggatgcacagcaggatgctgagcgaagctgcagccaccttggcaccatggtg
gagtttgcggtggcccttgggtctaagctggatgtcatcaacaagcactcattcaacaac
ttccgcctgcgtgtggggttgaaccatggacctgtggtggctggagtgataggggcccag
aagccacaatatgacatctggggcaacacagtgaatgtggccagccgcatggagagtaca
ggagtcctgggcaagatccaagtgactgaggagacagcccgtgccctgcagtccttaggt
tatacctgctacagccggggtgtcatcaaggtcaaaggcaaagggcagctgtgcacctac
ttcctgaacacagatttgacacgagttggacctccttcagccaccctgggctga

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