KEGG T02993: 102892254

Pteropus alecto (black flying fox): 102892254

Entry

102892254         CDS       T02993

Symbol

PPP1CA

Name

(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit

K06269

serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]

Organism

pale Pteropus alecto (black flying fox)

Pathway

pale03015

mRNA surveillance pathway

pale04022

cGMP-PKG signaling pathway

pale04024

cAMP signaling pathway

pale04114

Oocyte meiosis

pale04218

Cellular senescence

pale04261

Adrenergic signaling in cardiomyocytes

pale04270

Vascular smooth muscle contraction

pale04390

Hippo signaling pathway

pale04510

Focal adhesion

pale04611

Platelet activation

pale04720

Long-term potentiation

pale04728

Dopaminergic synapse

pale04750

Inflammatory mediator regulation of TRP channels

pale04810

Regulation of actin cytoskeleton

pale04910

Insulin signaling pathway

pale04921

Oxytocin signaling pathway

pale04931

Insulin resistance

pale05031

Amphetamine addiction

pale05034

Alcoholism

pale05168

Herpes simplex virus 1 infection

pale05205

Proteoglycans in cancer

pale05415

Diabetic cardiomyopathy

Brite

KEGG Orthology (KO) [BR:pale00001]
09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    102892254 (PPP1CA)
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    102892254 (PPP1CA)
   04024 cAMP signaling pathway
    102892254 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    102892254 (PPP1CA)
09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102892254 (PPP1CA)
   04218 Cellular senescence
    102892254 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102892254 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102892254 (PPP1CA)
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102892254 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102892254 (PPP1CA)
   04921 Oxytocin signaling pathway
    102892254 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102892254 (PPP1CA)
   04270 Vascular smooth muscle contraction
    102892254 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    102892254 (PPP1CA)
   04720 Long-term potentiation
    102892254 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102892254 (PPP1CA)
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102892254 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    102892254 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    102892254 (PPP1CA)
   05034 Alcoholism
    102892254 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    102892254 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102892254 (PPP1CA)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pale01009]
    102892254 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:pale03021]
    102892254 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:pale03019]
    102892254 (PPP1CA)
   03041 Spliceosome [BR:pale03041]
    102892254 (PPP1CA)
Enzymes [BR:pale01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     102892254 (PPP1CA)
Protein phosphatases and associated proteins [BR:pale01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     102892254 (PPP1CA)
Transcription machinery [BR:pale03021]
Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     102892254 (PPP1CA)
Messenger RNA biogenesis [BR:pale03019]
Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     102892254 (PPP1CA)
Spliceosome [BR:pale03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    102892254 (PPP1CA)

SSDB

Motif

Pfam:

Metallophos STPPase_N

Other DBs

NCBI-GeneID:

102892254

NCBI-ProteinID:

XP_006911089

UniProt:

L5KQ14

Position

Unknown

AA seq 330 aa
MTDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK

NT seq 993 nt +upstreamnt +downstreamnt
atgaccgacagcgagaagctcaacctggactctatcatcgggcgcctgctcgaagtgcag
ggctcccggcctggaaagaatgtacagctgacagagaacgagatccgtggtctgtgtctt
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacatccatggccagtactatgaccttctgcggctgttcgagtatggcggc
ttccctccagagagcaactacctcttcctgggggactatgtggaccgaggcaagcagtcg
ctggagaccatctgtctgctgctggcctataagatcaagtaccctgagaacttcttcctg
ctccgtgggaaccatgagtgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacattaaactgtggaaaaccttcaccgactgcttcaactgcctgccc
atcgctgccatcgtggatgagaagatcttctgctgccacggaggcctgtccccggacctg
cagtctatggaacagattcggcgtatcatgcggcccacagatgtgcctgaccaggggttg
ttatgtgacctgctgtggtccgaccccgacaaggacgtgcagggctggggcgagaacgac
cgtggtgtctcctttacttttggggccgaggtggtggccaagttcctgcacaagcacgac
ttggacctcatctgccgagcgcaccaggtggtagaagatggctacgagttctttgccaag
cggcagctggtgacactcttctcagctcccaactactgtggcgagtttgacaatgcaggc
gccatgatgagtgtggacgagacgctgatgtgctccttccagatcctaaagcccgccgac
aagaacaaggggaaatatgggcagttcagtggcctgaaccctggcgggcggcccatcacc
ccaccccgcaactccgccaaagccaagaaatag

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