KEGG   Pteropus alecto (black flying fox): 102898380
Entry
102898380         CDS       T02993                                 
Name
(RefSeq) steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale00140  Steroid hormone biosynthesis
pale01100  Metabolic pathways
pale04925  Aldosterone synthesis and secretion
pale04927  Cortisol synthesis and secretion
pale04934  Cushing syndrome
Module
pale_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:pale00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    102898380
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    102898380
   04927 Cortisol synthesis and secretion
    102898380
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102898380
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:pale00199]
    102898380
Enzymes [BR:pale01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     102898380
Cytochrome P450 [BR:pale00199]
 Cytochrome P450, animal type
  CYP21 family
   102898380
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 102898380
NCBI-ProteinID: XP_006904686
Position
Unknown
AA seq 494 aa
MLLLGLLLLTLLAGARLLWGQWKLRSLHLPPLVPGFLHLRQPNLPIYLLGLAQKLGPIYR
LRLGLQDVVVLNSKRTIEEAMIRKWVDFAGRPQSPSYKLVSRHNQDLSLGDYSLLWKAHK
RLTRSALLLGMRGSMEPLVEQLAQEFCERMRAQAGAPVAIQKEFSFLTCSIICYLTFGDK
VKEDTLVHAFHDCVQDLMKTWDHWSIQILHIIPFLRFFPNPGLWRLKQAVENRDHIVEKQ
LRQHKDSMVAGQWRDMMDYMLQGLGKPREEEGPGHLLEGHVHMSVVDLFIGGTETTSTTL
SWAVVFLLHHPEFQQRLQEELDRELGPRARGSRVPYKDRSRLPLLNATIAEVLRLRPVVP
LALPHRTTRPSSIFGYDIPEGTVVIPNLQGAHLDETVWERPHEFWPDRFLAPGASPSALA
FGCGARVCLGEPLARLELFVVLARLLQAFTLLPPVGALPSLQPHPHCGVNLTVPPFQVRL
QPRGAAPPGLGECQ
NT seq 1485 nt   +upstreamnt  +downstreamnt
atgctgctcctcgggctgctgctgctgaccttgctggctggtgcccgcctgttgtggggc
cagtggaagctcaggagcctccacctcccacctcttgttcctggcttcctgcacctgcgg
cagcccaacctccccatctatctgcttggcctggctcagaaacttgggcccatctacagg
ctccgccttggactgcaagatgtggtggtgctgaactctaagaggacaattgaggaggcc
atgatcaggaagtgggtggactttgctggcagaccccagtcaccatcctacaagctggtg
tcccggcacaaccaggacctctcgcttggggattactccctgctctggaaggcccacaag
agactcacccgctccgccttgctactgggcatgcgtggctccatggagcccctggtggag
cagctggcccaggagttctgtgagcgcatgagagcccaggccggtgcccctgtggccatc
cagaaggaattctccttcctcacctgcagcatcatctgctacctcacctttggagacaag
gtcaaggaggataccttagtacatgcctttcacgattgtgtccaggacttgatgaaaacc
tgggaccactggtccatccaaattttgcacatcattccttttctcaggttcttccccaac
ccaggcctctggaggctgaagcaggccgtggagaacagagaccacattgtagagaagcag
ctgaggcagcacaaggacagcatggtggcaggccagtggagggacatgatggactacatg
ctccagggcttggggaagccgagagaggaagagggccctggacatctccttgaaggacat
gtgcacatgtctgtggtggacctttttatcggtggcactgagactacttcaaccaccctc
tcctgggctgtggtgttcttgcttcaccaccctgagtttcagcagcgactacaagaggag
ttggatcgtgagctgggccccagagcccggggctcccgagtcccatacaaggaccgctca
cggctgcccttgctcaacgccaccattgcggaggtgctgcgcctgcggccagtcgtgccc
ttggccctgccgcaccgcaccactcggcctagcagcatcttcggctatgacatccccgag
ggcactgtcgtcatcccgaacctccaaggtgcccacctggacgagacagtctgggagcgg
ccacacgagttctggcctgatcgctttctggcccctggcgcaagccccagtgcactggcc
tttggctgcggggcacgtgtgtgcctgggcgagccgctggcacgcctggagctcttcgtg
gtgctggcgcgtctgctgcaggccttcacgctgctgccgccagtgggcgccctgccctcc
ctgcagccccacccccactgcggtgtcaacctcactgtgccgcctttccaggtgcggctg
cagccccggggggcagcgcccccaggcttgggcgagtgccagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (16)   
   KEGG COMPOUND (16)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (48)   

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