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Entry
map00190                    Pathway                                

Name
Oxidative phosphorylation
Class
Metabolism; Energy metabolism
BRITE hierarchy
Pathway map
map00190  Oxidative phosphorylation
map00190

Ortholog table
Module
M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:map00190]
M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:map00190]
M00144  NADH:quinone oxidoreductase, prokaryotes [PATH:map00190]
M00145  NAD(P)H:quinone oxidoreductase, chloroplasts and cyanobacteria [PATH:map00190]
M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:map00190]
M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:map00190]
M00148  Succinate dehydrogenase (ubiquinone) [PATH:map00190]
M00149  Succinate dehydrogenase, prokaryotes [PATH:map00190]
M00150  Fumarate reductase, prokaryotes [PATH:map00190]
M00151  Cytochrome bc1 complex respiratory unit [PATH:map00190]
M00152  Cytochrome bc1 complex [PATH:map00190]
M00153  Cytochrome bd ubiquinol oxidase [PATH:map00190]
M00154  Cytochrome c oxidase [PATH:map00190]
M00155  Cytochrome c oxidase, prokaryotes [PATH:map00190]
M00156  Cytochrome c oxidase, cbb3-type [PATH:map00190]
M00157  F-type ATPase, prokaryotes and chloroplasts [PATH:map00190]
M00158  F-type ATPase, eukaryotes [PATH:map00190]
M00159  V/A-type ATPase, prokaryotes [PATH:map00190]
M00160  V-type ATPase, eukaryotes [PATH:map00190]
M00416  Cytochrome aa3-600 menaquinol oxidase [PATH:map00190]
M00417  Cytochrome o ubiquinol oxidase [PATH:map00190]
Disease
H00068  Leber hereditary optic atrophy
H00473  Mitochondrial complex I deficiency
H00920  Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis
H01177  Infantile bilateral striatal necrosis
H01200  Fatal infantile cardioencephalomyopathy
H01347  MELAS Syndrome
H01354  Leigh syndrome
H01355  Kearns-Sayre syndrome
H01356  Myoclonic Epilepsy and Ragged-Red Fiber Disease
H01363  NARP syndrome
H01365  Leber hereditary optic neuropathy and dystonia
H01368  Cytochrome c oxidase (COX) deficiency
H01369  ATP synthase deficiency
H01904  Microphthalmia with linear skin defects syndrome
H02005  Mitochondrial complex II deficiency
H02086  Mitochondrial complex III deficiency
Reference
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   

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