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Entry
map00230                    Pathway                                

Name
Purine metabolism
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
map00230  Purine metabolism
map00230

Ortholog table
Module
M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:map00230]
M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:map00230]
M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:map00230]
M00050  Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:map00230]
M00546  Purine degradation, xanthine => urea [PATH:map00230]
Disease
H00184  Hypermethioninemia
H00192  Xanthinuria
H00194  Lesch-Nyhan syndrome
H00195  Adenine phosphoribosyltransferase deficiency
H00196  Phosphoribosylpyrophosphate synthetase superactivity
H00197  Adenylosuccinate lyase deficiency
H00469  Mitochondrial DNA depletion syndrome
H00481  Cone-rod dystrophy and cone dystrophy
H00494  Desbuquois syndrome
H00674  Anemia due to disorders of nucleotide metabolism
H00761  SEMD, Pakistani type
H00824  Calcification of joints and arteries
H00837  Leber congenital amaurosis
H00946  Arts syndrome
H00966  AICA-ribosiduria
H01002  Generalized arterial calcification of infancy
H01096  Pyruvate kinase deficiency
H01128  Reticular dysgenesis
H01394  Cole disease
H01532  Gout
H01570  Autosomal dominant striatal degeneration
H02237  AMP deaminase deficiency
H02309  Adenosine deaminase deficiency
Other DBs
GO: 0042278
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
KO pathway
ko00230   

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