Entry |
|
Name |
Valine, leucine and isoleucine degradation
|
Class |
Metabolism; Amino acid metabolism
|
Pathway map |
map00280 | Valine, leucine and isoleucine degradation |

|
Module |
M00036 | Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:map00280] |
M00741 | Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:map00280] |
|
Disease |
H01076 | Alpha-methylacetoacetic aciduria |
H01121 | Succinyl CoA:3-oxoacid CoA transferase (SCOT) deficiency |
H01123 | HMG-CoA synthase deficiency |
H01279 | Isobutyryl-CoA dehydrogenase deficiency |
H01364 | 3-Hydroxyacyl-CoA dehydrogenase deficiency |
H01400 | Secondary hyperammonemia |
H02109 | Combined malonic and methylmalonic aciduria |
H02285 | Methylmalonate semialdehyde dehydrogenase deficiency |
|
Other DBs |
|
Related pathway |
map00290 | Valine, leucine and isoleucine biosynthesis |
map00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
map00900 | Terpenoid backbone biosynthesis |
map01056 | Biosynthesis of type II polyketide backbone |
|
KO pathway |
|