KEGG   PATHWAY: map00600
Entry
map00600                    Pathway                                
Name
Sphingolipid metabolism
Class
Metabolism; Lipid metabolism
Pathway map
map00600  Sphingolipid metabolism
map00600

Module
M00066  Lactosylceramide biosynthesis [PATH:map00600]
M00067  Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:map00600]
M00094  Ceramide biosynthesis [PATH:map00600]
M00099  Sphingosine biosynthesis [PATH:map00600]
M00100  Sphingosine degradation [PATH:map00600]
Other DBs
GO: 0006665
Reference
PMID:12011104
  Authors
Merrill AH Jr.
  Title
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
  Journal
J Biol Chem 277:25843-6 (2002)
DOI:10.1074/jbc.R200009200
Reference
PMID:10652340
  Authors
Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
  Title
Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
  Journal
J Biol Chem 275:3462-8 (2000)
DOI:10.1074/jbc.275.5.3462
Reference
PMID:11305904
  Authors
Hannun YA, Luberto C, Argraves KM.
  Title
Enzymes of sphingolipid metabolism: from modular to integrative signaling.
  Journal
Biochemistry 40:4893-903 (2001)
DOI:10.1021/bi002836k
Reference
PMID:1495423
  Authors
Merrill AH Jr, Wang E.
  Title
Enzymes of ceramide biosynthesis.
  Journal
Methods Enzymol 209:427-37 (1992)
DOI:10.1016/0076-6879(92)09053-6
Reference
PMID:8457204
  Authors
Hirschberg K, Rodger J, Futerman AH.
  Title
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
  Journal
Biochem J 290 ( Pt 3):751-7 (1993)
DOI:10.1042/bj2900751
Reference
PMID:10366774
  Authors
Dickson RC, Lester RL.
  Title
Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1438:305-21 (1999)
DOI:10.1016/S1388-1981(99)00068-2
Related
pathway
map00260  Glycine, serine and threonine metabolism
map00601  Glycosphingolipid biosynthesis - lacto and neolacto series
map00603  Glycosphingolipid biosynthesis - globo and isoglobo series
map00604  Glycosphingolipid biosynthesis - ganglio series
KO pathway
ko00600   

  All links  
Pathway (5)   
   KEGG MODULE (5)   
Chemical substance (35)   
   KEGG COMPOUND (35)   
Chemical reaction (87)   
   KEGG ENZYME (34)   
   KEGG REACTION (53)   
Gene (117036)   
   KEGG ORTHOLOGY (52)   
   RefGene (116984)   
Literature (6)   
   PubMed (6)   
All databases (117169)   

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