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Entry
map00970                    Pathway                                

Name
Aminoacyl-tRNA biosynthesis
Class
Genetic Information Processing; Translation
BRITE hierarchy
Pathway map
map00970  Aminoacyl-tRNA biosynthesis
map00970

Ortholog table
Module
M00359  Aminoacyl-tRNA biosynthesis, eukaryotes [PATH:map00970]
M00360  Aminoacyl-tRNA biosynthesis, prokaryotes [PATH:map00970]
Disease
H00264  Charcot-Marie-Tooth disease
H00871  Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation
H00897  Pontocerebellar hypoplasia
H00898  Myopathy with lactic acidosis and sideroblastic anaemia
H01347  MELAS Syndrome
H01351  Spastic ataxia
H01356  Myoclonic Epilepsy and Ragged-Red Fiber Disease
H01367  Infantile liver failure
H02095  Perrault syndrome
H02232  CAGSSS syndrome
Reference
  Authors
Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D
  Title
From one amino acid to another: tRNA-dependent amino acid biosynthesis.
  Journal
Nucleic Acids Res 36:1813-25 (2008)
DOI:10.1093/nar/gkn015
Reference
  Authors
Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D
  Title
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine.
  Journal
Proc Natl Acad Sci U S A 101:12450-4 (2004)
DOI:10.1073/pnas.0405362101
KO pathway
ko00970   

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