KEGG   PATHWAY: ave00290
Entry
ave00290                    Pathway                                

Name
Valine, leucine and isoleucine biosynthesis - Archaeoglobus veneficus
Class
Metabolism; Amino acid metabolism
Pathway map
ave00290  Valine, leucine and isoleucine biosynthesis
ave00290

Module
ave_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ave00290]
ave_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:ave00290]
ave_M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate [PATH:ave00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Archaeoglobus veneficus [GN:ave]
Gene
Arcve_1419  isopropylmalate/citramalate/homocitratesynthase [KO:K09011] [EC:2.3.1.182]
Arcve_0822  3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Arcve_0515  3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Arcve_0988  3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Arcve_1257  3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Arcve_0597  isopropylmalate/isohomocitrate dehydrogenase [KO:K00052] [EC:1.1.1.85]
Arcve_1420  acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
Arcve_1421  acetolactate synthase, small subunit [KO:K01653] [EC:2.2.1.6]
Arcve_1393  Ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
Arcve_1358  Dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
Arcve_1585  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
Arcve_1366  isopropylmalate/citramalate/homocitratesynthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
ave00260  Glycine, serine and threonine metabolism
ave00280  Valine, leucine and isoleucine degradation
ave00620  Pyruvate metabolism
KO pathway
ko00290   

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