KEGG   PATHWAY: avi00290
Entry
avi00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Allorhizobium ampelinum
Class
Metabolism; Amino acid metabolism
Pathway map
avi00290  Valine, leucine and isoleucine biosynthesis
avi00290

Module
avi_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:avi00290]
avi_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:avi00290]
avi_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:avi00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Allorhizobium ampelinum [GN:avi]
Gene
Avi_2496  ilvA; threonine dehydratase [KO:K01754] [EC:4.3.1.19]
Avi_9151  ilvA; threonine dehydratase [KO:K01754] [EC:4.3.1.19]
Avi_9636  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Avi_4223  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Avi_9634  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Avi_4358  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Avi_4359  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
Avi_2933  iivG; acetolactate synthase large subunit [KO:K01652] [EC:2.2.1.6]
Avi_2802  ilvI; acetolactate synthase III large subunit [KO:K01652] [EC:2.2.1.6]
Avi_2801  ilvN; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
Avi_2778  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
Avi_2414  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
Avi_1251  ilvE; branched-chain-amino-acid transaminase [KO:K00826] [EC:2.6.1.42]
Avi_1393  Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase protein [KO:K00826] [EC:2.6.1.42]
Avi_1477  isopropylmalate synthase protein [KO:K01649] [EC:2.3.3.13]
Avi_3249  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Avi_9608  isopropylmalate/homocitrate/citramalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
avi00260  Glycine, serine and threonine metabolism
avi00280  Valine, leucine and isoleucine degradation
avi00620  Pyruvate metabolism
KO pathway
ko00290   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG GENES (17)   
All databases (18)   

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