KEGG   PATHWAY: avr00290Help
Entry
avr00290                    Pathway                                

Name
Valine, leucine and isoleucine biosynthesis - Aeromonas veronii B565
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
avr00290  Valine, leucine and isoleucine biosynthesis
avr00290

Ortholog table
Module
avr_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:avr00290]
avr_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:avr00290]
avr_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:avr00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Aeromonas veronii B565 [GN:avr]
Gene
B565_3837  Threonine ammonia-lyase, biosynthetic [KO:K01754] [EC:4.3.1.19]
B565_1139  Threonine dehydratase catabolic [KO:K01754] [EC:4.3.1.19]
B565_3377  3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.35 4.2.1.33]
B565_3378  3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.35 4.2.1.33]
B565_3376  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
B565_3014  Acetolactate synthase, catabolic [KO:K01652] [EC:2.2.1.6]
B565_3841  acetolactate synthase 2 catalytic subunit [KO:K01652] [EC:2.2.1.6]
B565_3370  Acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
B565_3369  Acetolactate synthase isozyme III, small subunit [KO:K01653] [EC:2.2.1.6]
B565_3840  Acetolactate synthase II small subunit [KO:K11258] [EC:2.2.1.6]
B565_3924  Ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
B565_3838  Dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
B565_3839  Branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
B565_0009  Aminotransferase class I and II [KO:K00835] [EC:2.6.1.66]
B565_1290  aminotransferase YfbQ [KO:K14260] [EC:2.6.1.2 2.6.1.66]
B565_3375  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
KO pathway
ko00290   

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