KEGG   PATHWAY: dra00290Help
Entry
dra00290                    Pathway                                

Name
Valine, leucine and isoleucine biosynthesis - Deinococcus radiodurans
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
dra00290  Valine, leucine and isoleucine biosynthesis
dra00290

Ortholog table
Module
dra_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:dra00290]
dra_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:dra00290]
dra_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:dra00290]
Other DBs
BSID: 2578
GO: 0009097 0009098 0009099
Organism
Deinococcus radiodurans [GN:dra]
Gene
DR_0567  threonine dehydratase [KO:K01754] [EC:4.3.1.19]
DR_1778  3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.35 4.2.1.33]
DR_1784  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.35 4.2.1.33]
DR_1785  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
DR_1516  acetolactate synthase large subunit [KO:K01652] [EC:2.2.1.6]
DR_1517  ilvN; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
DR_1519  ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
DR_1132  dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
DR_1626  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
DR_0158  branched-chain amino acid dehydrogenase [KO:K00263] [EC:1.4.1.9]
DR_1482  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
KO pathway
ko00290   

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