KEGG PATHWAY: dse00564

KEGG

PATHWAY: dse00564

Entry

dse00564                    Pathway

Name

Glycerophospholipid metabolism - Drosophila sechellia

Class

Metabolism; Lipid metabolism

Pathway map

Glycerophospholipid metabolism

Module

Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:dse00564]

Other DBs

GO:

Organism

Drosophila sechellia [GN:dse]

Gene

glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]

glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]

glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]

glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]

glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]

glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1 [KO:K13509] [EC:2.3.1.51]

1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]

1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]

dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]

putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]

putative phosphatidate phosphatase isoform X1 [KO:K01080] [EC:3.1.3.4]

putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]

putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]

putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]

putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]

phosphatidate phosphatase LPIN3 isoform X2 [KO:K15728] [EC:3.1.3.4]

phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]

diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]

diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]

phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]

phospholipase D3 [KO:K16860] [EC:3.1.4.4]

phospholipase D3 [KO:K16860] [EC:3.1.4.4]

uncharacterized protein LOC6612478 isoform X1 [KO:K01047] [EC:3.1.1.4]

uncharacterized protein LOC6612678 [KO:K01047] [EC:3.1.1.4]

acidic phospholipase A2 PA4 [KO:K01047] [EC:3.1.1.4]

group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]

phospholipase A2 [KO:K01047] [EC:3.1.1.4]

phospholipase A2 large subunit [KO:K01047] [EC:3.1.1.4]

85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]

lysophosphatidylcholine acyltransferase [KO:K13510] [EC:2.3.1.23 2.3.1.67]

lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]

group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]

acyl-protein thioesterase 1 isoform X1 [KO:K06130] [EC:3.1.1.5]

neuropathy target esterase sws isoform X1 [KO:K14676] [EC:3.1.1.5]

glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]

choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]

acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]

venom carboxylesterase-6 [KO:K01049] [EC:3.1.1.7]

choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]

choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]

choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]

ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]

ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]

ethanolamine kinase isoform X1 [KO:K00894] [EC:2.7.1.82]

ethanolamine-phosphate cytidylyltransferase isoform X2 [KO:K00967] [EC:2.7.7.14]

alanine--glyoxylate aminotransferase 2-like [KO:K14286] [EC:4.2.3.2]

phosphatidate cytidylyltransferase, photoreceptor-specific [KO:K00981] [EC:2.7.7.41]

phosphatidylserine synthase 1 isoform X2 [KO:K08729] [EC:2.7.8.-]

phosphatidylserine decarboxylase proenzyme, mitochondrial [KO:K01613] [EC:4.1.1.65]

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]

probable cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]

tafazzin homolog [KO:K13511] [EC:2.3.1.-]

lysophospholipid acyltransferase 7 isoform X3 [KO:K13516] [EC:2.3.1.-]

Compound

Acyl-CoA

L-Serine

Acetaldehyde

sn-Glycerol 3-phosphate

Glycerone phosphate

Choline

Phosphatidylcholine

Ethanolamine

CDP-diacylglycerol

CDP-choline

Phosphatidylglycerol

Ethanolamine phosphate

Phosphatidylethanolamine

Phosphatidate

CDP-glycerol

CDP-ethanolamine

Choline phosphate

sn-Glycerol 1-phosphate

1,2-Diacyl-sn-glycerol

sn-Glycero-3-phosphocholine

1-Acyl-sn-glycerol 3-phosphate

1-Phosphatidyl-D-myo-inositol

N-Methylethanolamine phosphate

sn-Glycero-3-phosphoethanolamine

Phosphatidyl-N-methylethanolamine

Acetylcholine

Phosphatidylserine

Acylglycerone phosphate

1-Acylglycerophosphoinositol

L-Serine-phosphoethanolamine

Phosphatidylglycerophosphate

2-Acyl-sn-glycerol 3-phosphate

1-Acyl-sn-glycero-3-phosphocholine

2-Acyl-sn-glycero-3-phosphocholine

Phosphatidyl-N-dimethylethanolamine

1-Acyl-sn-glycero-3-phosphoethanolamine

3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

2-Acyl-sn-glycero-3-phosphoethanolamine

2-Acyl-sn-glycero-3-phosphoserine

Aminoacyl-phosphatidylglycerol

Cardiolipin

Triethanolamine

Diethanolamine

Phosphodimethylethanolamine

CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol

1-Acyl-sn-glycero-3-phosphoserine

1-Acyl-sn-glycero-3-phosphoglycerol

Monolysocardiolipin

Diacylglycerylhomoserine

Diacylglyceryl-N,N,N-trimethylhomoserine

2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine

2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate

Heptaprenylglyceryl phosphate

Heptaprenylglycerol

Diacetylheptaprenylglycerol

Reference

Authors

Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.

Title

The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.

Journal

J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992

Reference

Authors

Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.

Title

Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Journal

Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411

Reference

Authors

Athenstaedt K, Daum G.

Title

Phosphatidic acid, a key intermediate in lipid metabolism.

Journal

Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x

Reference

Authors

Shields DJ, Lehner R, Agellon LB, Vance DE.

Title

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

Journal

J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200

Reference

Authors

Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.

Title

Pathways for phosphatidylcholine biosynthesis in bacteria.

Journal

Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0

Reference

Authors

Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.

Title

Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.

Journal

Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007

Reference

Authors

Hsu L, Jackowski S, Rock CO

Title

Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Journal

J Biol Chem 266:13783-8 (1991)

Reference

Authors

Stone SJ, Vance JE.

Title

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.

Journal

J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200

Related
pathway

Glycolysis / Gluconeogenesis

Glycine, serine and threonine metabolism

Glycerolipid metabolism

Inositol phosphate metabolism

Glycosylphosphatidylinositol (GPI)-anchor biosynthesis

Ether lipid metabolism

Pyruvate metabolism

KO pathway

All links

Genome (1)   
   KEGG GENOME (1)   
Gene (54)   
   KEGG GENES (54)   
All databases (55)   

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