KEGG   PATHWAY: dsh00630Help
dsh00630                    Pathway                                

Glyoxylate and dicarboxylate metabolism - Dinoroseobacter shibae
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
dsh00630  Glyoxylate and dicarboxylate metabolism

Ortholog table
dsh_M00373  Ethylmalonyl pathway [PATH:dsh00630]
dsh_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:dsh00630]
Dinoroseobacter shibae [GN:dsh]
Dshi_1227  glcB; malate synthase G [KO:K01638] [EC:]
Dshi_2876  mdh; malate dehydrogenase [KO:K00024] [EC:]
Dshi_1806  gltA2; citrate synthase [KO:K01647] [EC:]
Dshi_3119  gltA1; citrate synthase [KO:K01647] [EC:]
Dshi_1851  acnA; aconitate hydratase 1 [KO:K01681] [EC:]
Dshi_2060  acnB; aconitate hydratase 2 [KO:K01682] [EC:]
Dshi_2492  sucD2; ADP-forming succinyl-CoA ligase [KO:K08692] [EC:]
Dshi_2491  sucC2; succinyl-CoA synthetase [KO:K14067] [EC:]
Dshi_3066  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:]
Dshi_3331  bktB; beta-ketothiolase [KO:K00626] [EC:]
Dshi_0074  thlA; acetyl-CoA acetyltransferase [KO:K00626] [EC:]
Dshi_0836  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:]
Dshi_3067  fabG1; acetoacetyl-CoA reductase [KO:K00023] [EC:]
Dshi_2926  putative MaoC-like dehydratase [KO:K17865] [EC:]
Dshi_2853  alcohol dehydrogenase [KO:K14446] [EC:]
Dshi_2630  putative glyoxalase [KO:K05606] [EC:]
Dshi_2855  mutB; methylmalonyl-CoA mutase [KO:K14447] [EC:]
Dshi_0204  mmgC; acyl-CoA dehydrogenase [KO:K14448] [EC:]
Dshi_2871  putative thiol ester dehydrase/isomerase [KO:K14449] [EC:]
Dshi_3050  citE2; citrate lyase subunit beta [KO:K08691] [EC:]
Dshi_2874  putative citrate lyase subunit beta [KO:K14451] [EC:]
Dshi_0723  pccA; carbamoyl-phosphate synthase L chain ATP-binding [KO:K01965] [EC:]
Dshi_0718  pccB; carboxyl transferase [KO:K01966] [EC:]
Dshi_0726  bhbA; methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:]
Dshi_2896  FAD-binding oxidoreductase/transferase [KO:K00104] [EC:]
Dshi_2895  hypothetical protein [KO:K11472]
Dshi_2894  hypothetical protein [KO:K11473]
Dshi_0316  gph; phosphoglycolate phosphatase [KO:K01091] [EC:]
Dshi_2760  putative phosphoglycolate phosphatase [KO:K01091] [EC:]
Dshi_2818  HAD-like hydrolase [KO:K01091] [EC:]
Dshi_1295  HAD-superfamily hydrolase [KO:K01091] [EC:]
Dshi_0887  sgaA2; serine--glyoxylate transaminase [KO:K00830] [EC:]
Dshi_2090  putative serine--glyoxylate aminotransferase [KO:K00830] [EC:]
Dshi_2489  putative serine--glyoxylate aminotransferase [KO:K00830] [EC:]
Dshi_3325  sgaA1; serine--glyoxylate aminotransferase [KO:K00830] [EC:]
Dshi_1867  glnT; glutamine synthetase 3 [KO:K01915] [EC:]
Dshi_1839  glnA; glutamine synthetase [KO:K01915] [EC:]
Dshi_2226  glutamine synthetase family protein [KO:K01915] [EC:]
Dshi_0821  glyA2; glycine hydroxymethyltransferase [KO:K00600] [EC:]
Dshi_2113  glyA1; serine hydroxymethyltransferase [KO:K00600] [EC:]
Dshi_2680  gcvP; decarboxylating glycine dehydrogenase [KO:K00281] [EC:]
Dshi_2682  gcvT2; aminomethyltransferase, glycine cleavage system T protein [KO:K00605] [EC:]
Dshi_1811  lpdV; dihydrolipoyl dehydrogenase [KO:K00382] [EC:]
Dshi_1966  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:]
Dshi_2886  lpd; dihydrolipoyl dehydrogenase [KO:K00382] [EC:]
Dshi_2681  gcvH; glycine cleavage system H protein [KO:K02437]
Dshi_3046  ttuD; Hydroxypyruvate reductase [KO:K11529] [EC:]
Dshi_2970  gyaR; glyoxylate reductase [KO:K00015] [EC:]
Dshi_0590  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K12972] [EC:]
Dshi_0775  ttuC; tartrate dehydrogenase [KO:K07246] [EC:]
Dshi_1768  eda; KHG/KDPG aldolase [KO:K01625] [EC:]
Dshi_1282  fdhA; formate dehydrogenase, alpha subunit [KO:K00123] [EC:]
Dshi_0504  fdnG; formate dehydrogenase alpha chain [KO:K00123] [EC:]
Dshi_1281  fdhB; respiratory-chain NADH dehydrogenase domain 51 kDa subunit [KO:K22515] [EC:]
Dshi_0505  fdnH; formate dehydrogenase iron-sulfur subunit [KO:K00124]
Dshi_0506  fdnI; formate dehydrogenase, gamma subunit [KO:K00127]
Dshi_2111  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:]
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
PMID:10978349 (EC5.3.1.22)
Njau RK, Herndon CA, Hawes JW.
Novel beta -hydroxyacid dehydrogenases in Escherichia coli and Haemophilusinfluenzae.
J Biol Chem 275:38780-6 (2000)
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
J Bacteriol 190:1366-74 (2008)
Erb TJ, Retey J, Fuchs G, Alber BE
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
J Biol Chem 283:32283-93 (2008)
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
Plant Cell 10:741-52 (1998)
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
Plant Physiol 140:444-56 (2006)
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
A methylaspartate cycle in haloarchaea.
Science 331:334-7 (2011)
Serrano JA, Bonete MJ
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
Biochim Biophys Acta 1520:154-62 (2001)
KO pathway

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