KEGG   PATHWAY: hsa04810
Entry
hsa04810                    Pathway                                
Name
Regulation of actin cytoskeleton - Homo sapiens (human)
Class
Cellular Processes; Cell motility
Pathway map
hsa04810  Regulation of actin cytoskeleton
hsa04810

Network
nt06167  Human cytomegalovirus (HCMV)
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
nt06183  Yersinia
nt06464  Amyotrophic lateral sclerosis
nt06541  Cytoskeleton in neurons
  Element
N00405  CXCR4-GNA12/13-Rho signaling pathway
N01068  ITGA/B-FAK-RAC signaling pathway
N01097  LPA-GNA12/13-RhoA signaling pathway
N01161  Actin polymerization
Drug
D01175  Carpronium chloride (JAN/INN)
D01840  Fasudil hydrochloride (JAN)
D03065  Becaplermin (USAN/INN)
D03115  Fasudil hydrochloride hydrate (JAN)
D03497  Cilengitide (USAN/INN)
D04492  Icatibant acetate (JAN/USAN)
D05338  Palifermin (USAN/INN)
D05716  Repifermin (USAN/INN)
D06319  Volociximab (USAN)
D07941  Fasudil (INN)
D09342  Etaracizumab (USAN/INN)
D09752  Carpronium chloride hydrate (JAN)
D10028  Valategrast hydrochloride (USAN)
D10374  Lifitegrast (USAN/INN)
D10392  Lifitegrast sodium (USAN)
D10463  Ripasudil hydrochloride hydrate (JAN/USAN)
D12722  Bexotegrast (USAN/INN)
D13006  Sigvotatug (USAN/INN)
D13014  Ripasudil (USAN/INN)
Other DBs
GO: 0030036
Organism
Homo sapiens (human) [GN:hsa]
Gene
10000  AKT3; RAC-gamma serine/threonine-protein kinase isoform 1 [KO:K04456] [EC:2.7.11.1]
10092  ARPC5; actin-related protein 2/3 complex subunit 5 isoform 1 [KO:K05754]
10093  ARPC4; actin-related protein 2/3 complex subunit 4 isoform a [KO:K05755]
10094  ARPC3; actin-related protein 2/3 complex subunit 3 isoform 1 [KO:K05756]
10095  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
10096  ACTR3; actin-related protein 3 isoform 1 [KO:K18584]
10097  ACTR2; actin-related protein 2 isoform b [KO:K17260]
10109  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
10152  ABI2; abl interactor 2 isoform d [KO:K05751]
10163  WASF2; actin-binding protein WASF2 isoform 1 [KO:K05748]
10297  APC2; adenomatous polyposis coli protein 2 isoform 1 [KO:K02085]
10298  PAK4; serine/threonine-protein kinase PAK 4 isoform 1 [KO:K05734] [EC:2.7.11.1]
103910  MYL12B; myosin regulatory light chain 12B [KO:K12757]
10398  MYL9; myosin regulatory light polypeptide 9 isoform a [KO:K12755]
10451  VAV3; guanine nucleotide exchange factor VAV3 isoform 1 [KO:K05730]
10458  BAIAP2; BAR/IMD domain-containing adapter protein 2 isoform 2 [KO:K05627]
10552  ARPC1A; actin-related protein 2/3 complex subunit 1A isoform 1 [KO:K05757]
10627  MYL12A; myosin regulatory light chain 12A isoform 1 [KO:K12757]
10672  GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform 1 [KO:K04639]
106821730  BUB1B-PAK6; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
1072  CFL1; cofilin-1 [KO:K05765]
1073  CFL2; cofilin-2 isoform 1 [KO:K05765]
10787  NCKAP1; nck-associated protein 1 isoform 1 [KO:K05750]
10788  IQGAP2; ras GTPase-activating-like protein IQGAP2 isoform 1 [KO:K05767]
110117499  P3R3URF-PIK3R3; LOC110117498-PIK3R3 readthrough [KO:K02649]
1128  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
1129  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
1131  CHRM3; muscarinic acetylcholine receptor M3 [KO:K04131]
1132  CHRM4; muscarinic acetylcholine receptor M4 [KO:K04132]
1133  CHRM5; muscarinic acetylcholine receptor M5 [KO:K04133]
128239  IQGAP3; ras GTPase-activating-like protein IQGAP3 [KO:K05767]
1398  CRK; adapter molecule crk isoform a [KO:K04438]
1399  CRKL; crk-like protein [KO:K04438]
1729  DIAPH1; protein diaphanous homolog 1 isoform 1 [KO:K05740]
1730  DIAPH2; protein diaphanous homolog 2 isoform 156 [KO:K05741]
1793  DOCK1; dedicator of cytokinesis protein 1 isoform 2 [KO:K13708]
1902  LPAR1; lysophosphatidic acid receptor 1 isoform a [KO:K04289]
1950  EGF; pro-epidermal growth factor isoform 1 preproprotein [KO:K04357]
1956  EGFR; epidermal growth factor receptor isoform a precursor [KO:K04361] [EC:2.7.10.1]
200576  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform 2 [KO:K00921] [EC:2.7.1.150]
207  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
208  AKT2; RAC-beta serine/threonine-protein kinase isoform 1 [KO:K04456] [EC:2.7.11.1]
2147  F2; prothrombin preproprotein [KO:K01313] [EC:3.4.21.5]
2149  F2R; proteinase-activated receptor 1 isoform 1 precursor [KO:K03914]
221178  SPATA13; spermatogenesis-associated protein 13 isoform 2 [KO:K05769]
2245  FGD1; FYVE, RhoGEF and PH domain-containing protein 1 [KO:K05720]
2246  FGF1; fibroblast growth factor 1 isoform 1 precursor [KO:K18496]
2247  FGF2; fibroblast growth factor 2 isoform 34 kDa [KO:K18497]
2248  FGF3; fibroblast growth factor 3 precursor [KO:K04358]
2249  FGF4; fibroblast growth factor 4 precursor [KO:K04358]
2250  FGF5; fibroblast growth factor 5 isoform 1 precursor [KO:K04358]
2251  FGF6; fibroblast growth factor 6 precursor [KO:K04358]
2252  FGF7; fibroblast growth factor 7 precursor [KO:K04358]
2253  FGF8; fibroblast growth factor 8 isoform E precursor [KO:K04358]
2254  FGF9; fibroblast growth factor 9 precursor [KO:K04358]
2255  FGF10; fibroblast growth factor 10 precursor [KO:K04358]
2260  FGFR1; fibroblast growth factor receptor 1 isoform 1 precursor [KO:K04362] [EC:2.7.10.1]
2261  FGFR3; fibroblast growth factor receptor 3 isoform 1 precursor [KO:K05094] [EC:2.7.10.1]
2263  FGFR2; fibroblast growth factor receptor 2 isoform 1 precursor [KO:K05093] [EC:2.7.10.1]
2264  FGFR4; fibroblast growth factor receptor 4 isoform 1 precursor [KO:K05095] [EC:2.7.10.1]
22800  RRAS2; ras-related protein R-Ras2 isoform a [KO:K07830]
22801  ITGA11; integrin alpha-11 precursor [KO:K06587]
22808  MRAS; ras-related protein M-Ras isoform 1 precursor [KO:K07831]
23191  CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform a [KO:K05749]
2335  FN1; fibronectin isoform 1 precursor [KO:K05717]
23365  ARHGEF12; rho guanine nucleotide exchange factor 12 isoform 1 [KO:K07532]
23396  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform 2 [KO:K00889] [EC:2.7.1.68]
26281  FGF20; fibroblast growth factor 20 [KO:K04358]
26291  FGF21; fibroblast growth factor 21 precursor [KO:K22429]
26999  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform c [KO:K05749]
27006  FGF22; fibroblast growth factor 22 isoform 1 precursor [KO:K04358]
2768  GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform 1 [KO:K04346]
2846  LPAR4; lysophosphatidic acid receptor 4 [KO:K04275]
28964  GIT1; ARF GTPase-activating protein GIT1 isoform 2 [KO:K05737]
28984  RGCC; regulator of cell cycle RGCC [KO:K26108]
2909  ARHGAP35; rho GTPase-activating protein 35 [KO:K05732]
2934  GSN; gelsolin isoform a precursor [KO:K05768]
29895  MYL11; myosin regulatory light chain 11 [KO:K12758]
3071  NCKAP1L; nck-associated protein 1-like isoform 1 [KO:K05750]
324  APC; adenomatous polyposis coli protein isoform b [KO:K02085]
3265  HRAS; GTPase HRas isoform 1 [KO:K02833]
340156  MYLK4; myosin light chain kinase family member 4 isoform 1 [KO:K00907] [EC:2.7.11.18]
345456  PFN3; profilin-3 [KO:K05759]
3630  INS; insulin preproprotein [KO:K04526]
3645  INSRR; insulin receptor-related protein precursor [KO:K05086] [EC:2.7.10.1]
3655  ITGA6; integrin alpha-6 isoform 6 precursor [KO:K06485]
3672  ITGA1; integrin alpha-1 precursor [KO:K06480]
3673  ITGA2; integrin alpha-2 precursor [KO:K06481]
3674  ITGA2B; integrin alpha-IIb preproprotein [KO:K06476]
3675  ITGA3; integrin alpha-3 preproprotein [KO:K06482]
3676  ITGA4; integrin alpha-4 isoform 1 preproprotein [KO:K06483]
3678  ITGA5; integrin alpha-5 precursor [KO:K06484]
3679  ITGA7; integrin alpha-7 isoform 7 precursor [KO:K06583]
3680  ITGA9; integrin alpha-9 precursor [KO:K06585]
3681  ITGAD; integrin alpha-D isoform 2 precursor [KO:K06594]
3682  ITGAE; integrin alpha-E isoform 1 precursor [KO:K06524]
3683  ITGAL; integrin alpha-L isoform a precursor [KO:K05718]
3684  ITGAM; integrin alpha-M isoform 2 precursor [KO:K06461]
3685  ITGAV; integrin alpha-V isoform 1 preproprotein [KO:K06487]
3687  ITGAX; integrin alpha-X isoform 2 precursor [KO:K06462]
3688  ITGB1; integrin beta-1 isoform 1A precursor [KO:K05719]
3689  ITGB2; integrin beta-2 isoform 1 precursor [KO:K06464]
369  ARAF; serine/threonine-protein kinase A-Raf isoform 1 [KO:K08845] [EC:2.7.11.1]
3690  ITGB3; integrin beta-3 precursor [KO:K06493]
3691  ITGB4; integrin beta-4 isoform 1 precursor [KO:K06525]
3693  ITGB5; integrin beta-5 isoform a precursor [KO:K06588]
3694  ITGB6; integrin beta-6 isoform a precursor [KO:K06589]
3695  ITGB7; integrin beta-7 isoform a precursor [KO:K06590]
3696  ITGB8; integrin beta-8 precursor [KO:K06591]
375189  PFN4; profilin-4 [KO:K05759]
3827  KNG1; kininogen-1 isoform 1 precursor [KO:K03898]
3845  KRAS; GTPase KRas isoform a [KO:K07827]
387  RHOA; transforming protein RhoA isoform 1 precursor [KO:K04513]
3984  LIMK1; LIM domain kinase 1 isoform 1 [KO:K05743] [EC:2.7.11.1]
3985  LIMK2; LIM domain kinase 2 isoform 2a [KO:K05744] [EC:2.7.11.1]
4342  MOS; proto-oncogene serine/threonine-protein kinase mos [KO:K04367] [EC:2.7.11.1]
4478  MSN; moesin isoform 1 [KO:K05763]
4627  MYH9; myosin-9 [KO:K10352]
4628  MYH10; myosin-10 isoform 2 [KO:K10352]
4629  MYH11; myosin-11 isoform SM1A [KO:K10352]
4633  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform 1 [KO:K10351]
4636  MYL5; myosin light chain 5 isoform 1 [KO:K12753]
4638  MYLK; myosin light chain kinase, smooth muscle isoform 1 [KO:K00907] [EC:2.7.11.18]
4659  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform a [KO:K06270]
4660  PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform a [KO:K12329]
4893  NRAS; GTPase NRas [KO:K07828]
5058  PAK1; serine/threonine-protein kinase PAK 1 isoform 2 [KO:K04409] [EC:2.7.11.1]
5062  PAK2; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
5063  PAK3; serine/threonine-protein kinase PAK 3 isoform d [KO:K05733] [EC:2.7.11.1]
50649  ARHGEF4; rho guanine nucleotide exchange factor 4 isoform a [KO:K05769]
5154  PDGFA; platelet-derived growth factor subunit A isoform 1 preproprotein [KO:K04359]
5155  PDGFB; platelet-derived growth factor subunit B isoform 1 preproprotein [KO:K17386]
5156  PDGFRA; platelet-derived growth factor receptor alpha isoform 1 precursor [KO:K04363] [EC:2.7.10.1]
51571  CYRIB; CYFIP-related Rac1 interactor B isoform 1 [KO:K27976]
5159  PDGFRB; platelet-derived growth factor receptor beta isoform 1 precursor [KO:K05089] [EC:2.7.10.1]
5216  PFN1; profilin-1 isoform 2 [KO:K05759]
5217  PFN2; profilin-2 isoform b [KO:K05759]
5290  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
5291  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1 [KO:K00922] [EC:2.7.1.153]
5293  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform 1 [KO:K00922] [EC:2.7.1.153]
5295  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1 [KO:K02649]
5296  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
5305  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 1 [KO:K00920] [EC:2.7.1.149]
54434  SSH1; protein phosphatase Slingshot homolog 1 isoform 1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
54776  PPP1R12C; protein phosphatase 1 regulatory subunit 12C isoform a [KO:K17457]
54961  SSH3; protein phosphatase Slingshot homolog 3 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
5499  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 1 [KO:K06269] [EC:3.1.3.16]
5500  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform 1 [KO:K06269] [EC:3.1.3.16]
5501  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 1 [KO:K06269] [EC:3.1.3.16]
55740  ENAH; protein enabled homolog isoform a [KO:K05746]
55845  BRK1; protein BRICK1 [KO:K05752]
5594  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
5595  MAPK3; mitogen-activated protein kinase 3 isoform 1 [KO:K04371] [EC:2.7.11.24]
55970  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
56034  PDGFC; platelet-derived growth factor C precursor [KO:K05450]
5604  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform 1 [KO:K04368] [EC:2.7.12.2]
5605  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform 1 [KO:K04369] [EC:2.7.12.2]
56924  PAK6; serine/threonine-protein kinase PAK 6 isoform 1 [KO:K05735] [EC:2.7.11.1]
57121  LPAR5; lysophosphatidic acid receptor 5 [KO:K08390]
57144  PAK5; serine/threonine-protein kinase PAK 5 [KO:K05736] [EC:2.7.11.1]
57180  ACTR3B; actin-related protein 3B isoform 1 [KO:K18584]
5747  PTK2; focal adhesion kinase 1 isoform 1 [KO:K05725] [EC:2.7.10.2]
5829  PXN; paxillin isoform 2 [KO:K05760]
58498  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
5879  RAC1; ras-related C3 botulinum toxin substrate 1 isoform Rac1 [KO:K04392]
5880  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
5881  RAC3; ras-related C3 botulinum toxin substrate 3 isoform 1 [KO:K07861]
5894  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform b [KO:K04366] [EC:2.7.11.1]
5962  RDX; radixin isoform 2 [KO:K05762]
60  ACTB; actin, cytoplasmic 1 [KO:K05692]
6093  ROCK1; rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.39]
623  BDKRB1; B1 bradykinin receptor [KO:K03915]
6237  RRAS; ras-related protein R-Ras [KO:K07829]
624  BDKRB2; B2 bradykinin receptor [KO:K03916]
6387  CXCL12; stromal cell-derived factor 1 isoform beta precursor [KO:K10031]
653857  ACTR3C; actin-related protein 3C isoform a precursor [KO:K18584]
6548  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
6654  SOS1; son of sevenless homolog 1 isoform 1 [KO:K03099]
6655  SOS2; son of sevenless homolog 2 isoform 1 [KO:K03099]
6714  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
673  BRAF; serine/threonine-protein kinase B-raf isoform 1 [KO:K04365] [EC:2.7.11.1]
7074  TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform 1 [KO:K05731]
71  ACTG1; actin, cytoplasmic 2 [KO:K05692]
7114  TMSB4X; thymosin beta-4 [KO:K05764]
727  C5; complement C5 isoform 1 preproprotein [KO:K03994]
729  C6; complement component C6 precursor [KO:K03995]
730  C7; complement component C7 precursor [KO:K03996]
731  C8A; complement component C8 alpha chain preproprotein [KO:K03997]
732  C8B; complement component C8 beta chain isoform 1 preproprotein [KO:K03998]
733  C8G; complement component C8 gamma chain precursor [KO:K03999]
735  C9; complement component C9 preproprotein [KO:K04000]
7409  VAV1; proto-oncogene vav isoform 1 [KO:K05730]
7410  VAV2; guanine nucleotide exchange factor VAV2 isoform 1 [KO:K05730]
7414  VCL; vinculin isoform meta-VCL [KO:K05700]
7430  EZR; ezrin [KO:K08007]
7852  CXCR4; C-X-C chemokine receptor type 4 isoform b [KO:K04189]
79784  MYH14; myosin-14 isoform 2 [KO:K10352]
79837  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform a [KO:K00920] [EC:2.7.1.149]
80310  PDGFD; platelet-derived growth factor D isoform 1 precursor [KO:K05450]
8074  FGF23; fibroblast growth factor 23 precursor [KO:K22428]
81  ACTN4; alpha-actinin-4 isoform 1 [KO:K05699]
81553  CYRIA; CYFIP-related Rac1 interactor A [KO:K27976]
81624  DIAPH3; protein diaphanous homolog 3 isoform a [KO:K05745]
81873  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
8394  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform 1 [KO:K00889] [EC:2.7.1.68]
8395  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2 [KO:K00889] [EC:2.7.1.68]
8396  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
8503  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform 1 [KO:K02649]
8515  ITGA10; integrin alpha-10 isoform 1 precursor [KO:K06586]
8516  ITGA8; integrin alpha-8 isoform 1 preproprotein [KO:K06584]
85366  MYLK2; myosin light chain kinase 2, skeletal/cardiac muscle [KO:K00907] [EC:2.7.11.18]
85464  SSH2; protein phosphatase Slingshot homolog 2 isoform 2 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
85477  SCIN; scinderin isoform 1 [KO:K05768]
87  ACTN1; alpha-actinin-1 isoform b [KO:K05699]
8817  FGF18; fibroblast growth factor 18 precursor [KO:K04358]
8822  FGF17; fibroblast growth factor 17 isoform 1 precursor [KO:K04358]
8823  FGF16; fibroblast growth factor 16 [KO:K04358]
8826  IQGAP1; ras GTPase-activating-like protein IQGAP1 [KO:K16848]
8874  ARHGEF7; rho guanine nucleotide exchange factor 7 isoform c [KO:K13710]
8936  WASF1; actin-binding protein WASF1 [KO:K05753]
8976  WASL; actin nucleation-promoting factor WASL [KO:K23612]
89846  FGD3; FYVE, RhoGEF and PH domain-containing protein 3 isoform a [KO:K05722]
9087  TMSB4Y; thymosin beta-4, Y-chromosomal [KO:K05764]
9138  ARHGEF1; rho guanine nucleotide exchange factor 1 isoform 2 [KO:K12330]
9170  LPAR2; lysophosphatidic acid receptor 2 [KO:K04291]
91807  MYLK3; myosin light chain kinase 3 isoform 1 [KO:K00907] [EC:2.7.11.18]
93408  MYL10; myosin regulatory light chain 10 [KO:K12756]
9459  ARHGEF6; rho guanine nucleotide exchange factor 6 isoform 1 [KO:K05729]
9475  ROCK2; rho-associated protein kinase 2 isoform 1 [KO:K17388] [EC:2.7.11.39]
9564  BCAR1; breast cancer anti-estrogen resistance protein 1 isoform 6 [KO:K05726]
9965  FGF19; fibroblast growth factor 19 precursor [KO:K22603]
998  CDC42; cell division control protein 42 homolog isoform 1 precursor [KO:K04393]
Compound
C00681  1-Acyl-sn-glycerol 3-phosphate
C01996  Acetylcholine
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:11152757
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
DOI:10.1152/physrev.2001.81.1.153
Reference
PMID:12700767
  Authors
Pollard TD.
  Title
The cytoskeleton, cellular motility and the reductionist agenda.
  Journal
Nature 422:741-5 (2003)
DOI:10.1038/nature01598
Reference
PMID:14657486
  Authors
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.
  Title
Cell migration: integrating signals from front to back.
  Journal
Science 302:1704-9 (2003)
DOI:10.1126/science.1092053
Reference
PMID:11082272
  Authors
Sastry SK, Burridge K.
  Title
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics.
  Journal
Exp Cell Res 261:25-36 (2000)
DOI:10.1006/excr.2000.5043
Reference
PMID:10574699
  Authors
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K.
  Title
Cell adhesion and Rho small GTPases.
  Journal
J Cell Sci 112 ( Pt 24):4491-500 (1999)
Related
pathway
hsa04010  MAPK signaling pathway
hsa04510  Focal adhesion
hsa04520  Adherens junction
KO pathway
ko04810   

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