KEGG   PATHWAY: isc00053Help
Entry
isc00053                    Pathway                                

Name
Ascorbate and aldarate metabolism - Ixodes scapularis (black-legged tick)
Class
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
isc00053  Ascorbate and aldarate metabolism
isc00053

Ortholog table
Other DBs
BSID: 145830
GO: 0019852 0019572
Organism
Ixodes scapularis (black-legged tick) [GN:isc]
Gene
IscW_ISCW009911  UDP-glucose dehydrogenase, putative [KO:K00012] [EC:1.1.1.22]
IscW_ISCW010163  calcium-binding protein, putative [KO:K01053] [EC:3.1.1.17]
IscW_ISCW005090  calcium-binding protein, putative [KO:K01053] [EC:3.1.1.17]
IscW_ISCW015963  D-arabinono-1, 4-lactone oxidase, putative [KO:K00103] [EC:1.1.3.8]
IscW_ISCW014613  aldehyde dehydrogenase, putative [KO:K00128] [EC:1.2.1.3]
IscW_ISCW009197  aldehyde dehydrogenase, putative [KO:K00128] [EC:1.2.1.3]
IscW_ISCW012533  hypothetical protein [KO:K00128] [EC:1.2.1.3]
IscW_ISCW023288  aldehyde dehydrogenase, putative [KO:K00128] [EC:1.2.1.3]
IscW_ISCW003921  aldehyde dehydrogenase, putative [KO:K00128] [EC:1.2.1.3]
IscW_ISCW003922  aldehyde dehydrogenase, putative [KO:K00128] [EC:1.2.1.3]
IscW_ISCW020189  aldehyde dehydrogenase, putative [KO:K14085] [EC:1.2.1.3 1.2.1.8 1.2.1.31]
IscW_ISCW008939  aldehyde dehydrogenase, putative [KO:K00149] [EC:1.2.1.3 1.2.1.47]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00618  3-Dehydro-L-gulonate
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
Reference
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
KO pathway
ko00053   

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