KEGG   PATHWAY: mgp00564
Entry
mgp00564                    Pathway                                
Name
Glycerophospholipid metabolism - Meleagris gallopavo (turkey)
Class
Metabolism; Lipid metabolism
Pathway map
mgp00564  Glycerophospholipid metabolism
mgp00564

Module
mgp_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:mgp00564]
mgp_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:mgp00564]
mgp_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:mgp00564]
Other DBs
GO: 0006650
Organism
Meleagris gallopavo (turkey) [GN:mgp]
Gene
100550137  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
100547788  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
100542199  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
100546408  glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
100545045  GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
100547891  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
100541788  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
100545367  GPAT3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
100544441  glycerol-3-phosphate acyltransferase 3-like isoform X1 [KO:K13506] [EC:2.3.1.15]
100548108  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
100539227  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
104913689  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
100550577  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
100548232  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
100544175  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
100541035  lysocardiolipin acyltransferase 1-like isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
100548793  MBOAT2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
100549156  MBOAT1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
100543913  GNPAT; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
100544671  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
100547177  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
100551396  phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
100550008  PLPP1; phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
100551046  LPIN2; LOW QUALITY PROTEIN: phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
104909978  phosphatidate phosphatase LPIN1-like [KO:K15728] [EC:3.1.3.4]
100547192  PLPP5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
100540597  PLPP4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
100546131  diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
100548310  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
100551345  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
100539399  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
100543093  DGKK; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
100544032  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
100545115  DGKB; diacylglycerol kinase beta isoform X3 [KO:K00901] [EC:2.7.1.107]
104915334  DGKQ; LOW QUALITY PROTEIN: diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
100549171  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
104917525  diacylglycerol kinase eta-like [KO:K00901] [EC:2.7.1.107]
100546891  cholinephosphotransferase 1-like [KO:K00994] [EC:2.7.8.2]
100550822  CEPT1; choline/ethanolaminephosphotransferase 1 isoform X2 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
100547741  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
100540590  PLD4; phospholipase D4 isoform X1 [KO:K16860] [EC:3.1.4.4]
100539055  LCAT; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
100539729  group IIE secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
104914211  phospholipase A2, membrane associated-like [KO:K01047] [EC:3.1.1.4]
100543487  phospholipase A2, minor isoenzyme [KO:K01047] [EC:3.1.1.4]
100542392  PLA2G10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
100551192  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
100543329  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
100543922  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
100546810  PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
104913968  PROCA1; protein PROCA1 [KO:K01047] [EC:3.1.1.4]
100551023  phospholipase A2 crotoxin basic chain-like [KO:K01047] [EC:3.1.1.4]
116216161  basic phospholipase A2 Cdr-13-like [KO:K01047] [EC:3.1.1.4]
100549476  PLA2G4A; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
100543562  LOW QUALITY PROTEIN: cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
100542475  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
100542789  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
100543408  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
109367730  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
104911084  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
109367980  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
100549498  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
100546393  PLB1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
100547104  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
100546916  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
100541281  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
100549310  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
100544768  PLA2G15; group XV phospholipase A2 isoform X2 [KO:K06129] [EC:3.1.1.5]
100539114  LYPLA2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
104917191  PNPLA6; neuropathy target esterase isoform X1 [KO:K14676] [EC:3.1.1.5]
100550925  PNPLA7; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
100543090  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
100543253  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
104916025  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
100548595  CHKA; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
100547041  PHOSPHO1; LOW QUALITY PROTEIN: phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
100549987  PCYT1A; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
100548633  choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
100548385  SELENOI; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
100546243  ethanolaminephosphotransferase 1-like [KO:K00993] [EC:2.7.8.1]
100548227  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
100543800  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
100543267  PCYT2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
100542369  ETNPPL; ethanolamine-phosphate phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
100543379  phosphatidylethanolamine N-methyltransferase-like [KO:K00551] [EC:2.1.1.17 2.1.1.71]
104913413  phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
100539730  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
100545832  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
100546329  PLA1A; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
100546293  PTDSS1; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
100540844  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
100548052  PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial [KO:K01613] [EC:4.1.1.65]
100547750  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
100543402  CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
104916240  TAZ; tafazzin [KO:K13511] [EC:2.3.1.-]
100539903  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
mgp00010  Glycolysis / Gluconeogenesis
mgp00260  Glycine, serine and threonine metabolism
mgp00561  Glycerolipid metabolism
mgp00562  Inositol phosphate metabolism
mgp00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
mgp00565  Ether lipid metabolism
mgp00620  Pyruvate metabolism
KO pathway
ko00564   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (96)   
   KEGG GENES (96)   
All databases (97)   

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