KEGG   PATHWAY: ndi03410
Entry
ndi03410                    Pathway                                
Name
Base excision repair - Naumovozyma dairenensis
Description
Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates.
Class
Genetic Information Processing; Replication and repair
Pathway map
ndi03410  Base excision repair
ndi03410

Other DBs
GO: 0006284 0006285 0006286 0006287 0006288
Organism
Naumovozyma dairenensis [GN:ndi]
Gene
NDAI_0D04790  NDAI0D04790; hypothetical protein [KO:K03660] [EC:3.2.2.- 4.2.99.18]
NDAI_0H02450  NDAI0H02450; hypothetical protein [KO:K10773] [EC:3.2.2.- 4.2.99.18]
NDAI_0C00910  NDAI0C00910; hypothetical protein [KO:K03648] [EC:3.2.2.27]
NDAI_0K01490  NDAI0K01490; hypothetical protein [KO:K10771] [EC:3.1.11.2]
NDAI_0F01850  NDAI0F01850; hypothetical protein [KO:K10862] [EC:3.1.4.-]
NDAI_0E01030  NDAI0E01030; hypothetical protein [KO:K10863] [EC:3.6.1.70 3.6.1.71 3.6.1.72]
NDAI_0E03810  NDAI0E03810; hypothetical protein [KO:K02332] [EC:2.7.7.7]
NDAI_0B03180  NDAI0B03180; hypothetical protein [KO:K02327] [EC:2.7.7.7]
NDAI_0C02800  NDAI0C02800; hypothetical protein [KO:K02328]
NDAI_0G04780  NDAI0G04780; hypothetical protein [KO:K03504]
NDAI_0F04140  NDAI0F04140; hypothetical protein [KO:K02324] [EC:2.7.7.7]
NDAI_0J00310  NDAI0J00310; hypothetical protein [KO:K02325] [EC:2.7.7.7]
NDAI_0J01260  NDAI0J01260; hypothetical protein [KO:K02326] [EC:2.7.7.7]
NDAI_0B04830  NDAI0B04830; hypothetical protein [KO:K03506] [EC:2.7.7.7]
NDAI_0G05730  NDAI0G05730; hypothetical protein [KO:K03506] [EC:2.7.7.7]
NDAI_0A07740  NDAI0A07740; hypothetical protein [KO:K04802]
NDAI_0E01440  NDAI0E01440; hypothetical protein [KO:K10754]
NDAI_0A03940  NDAI0A03940; hypothetical protein [KO:K10755]
NDAI_0G05150  NDAI0G05150; hypothetical protein [KO:K10755]
NDAI_0A05340  NDAI0A05340; hypothetical protein [KO:K10756]
NDAI_0A06060  NDAI0A06060; hypothetical protein [KO:K10756]
NDAI_0H02290  NDAI0H02290; hypothetical protein [KO:K04799] [EC:3.1.-.-]
NDAI_0A01940  NDAI0A01940; hypothetical protein [KO:K10747] [EC:6.5.1.1 6.5.1.6 6.5.1.7]
NDAI_0B03050  NDAI0B03050; hypothetical protein [KO:K01247] [EC:3.2.2.21]
Reference
  Authors
Krwawicz J, Arczewska KD, Speina E, Maciejewska A, Grzesiuk E.
  Title
Bacterial DNA repair genes and their eukaryotic homologues: 1. Mutations in genes involved in base excision repair (BER) and DNA-end processors and their implication in mutagenesis and human disease.
  Journal
Acta Biochim Pol 54:413-34 (2007)
Reference
  Authors
Almeida KH, Sobol RW.
  Title
A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification.
  Journal
DNA Repair (Amst) 6:695-711 (2007)
DOI:10.1016/j.dnarep.2007.01.009
Reference
  Authors
Moen MN, Knaevelsrud I, Haugland GT, Grosvik K, Birkeland NK, Klungland A, Bjelland S
  Title
Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair.
  Journal
J Bacteriol 193:4495-508 (2011)
DOI:10.1128/JB.00233-11
Reference
  Authors
Ikeda S, Seki S.
  Title
[Base excision repair: DNA glycosylase and AP endonuclease]
  Journal
Tanpakushitsu Kakusan Koso 46:916-23 (2001)
KO pathway
ko03410   

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