KEGG   PATHWAY: nve00230
Entry
nve00230                    Pathway                                
Name
Purine metabolism - Nematostella vectensis (starlet sea anemone)
Class
Metabolism; Nucleotide metabolism
Pathway map
nve00230  Purine metabolism
nve00230

Module
nve_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:nve00230]
nve_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:nve00230]
nve_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:nve00230]
nve_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:nve00230]
nve_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:nve00230]
nve_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:nve00230]
nve_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:nve00230]
Other DBs
GO: 0006163 0042278
Organism
Nematostella vectensis (starlet sea anemone) [GN:nve]
Gene
5502481  ADP-ribose pyrophosphatase, mitochondrial isoform X2 [KO:K13988] [EC:3.6.1.13]
5509830  phosphoglucomutase-1 isoform X1 [KO:K01835] [EC:5.4.2.2]
5516421  glucose 1,6-bisphosphate synthase [KO:K15779] [EC:5.4.2.2 5.4.2.7]
5519267  ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
5500616  amidophosphoribosyltransferase isoform X1 [KO:K00764] [EC:2.4.2.14]
5509911  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
5521892  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
5500615  multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
5516867  adenylosuccinate lyase isoform X1 [KO:K01756] [EC:4.3.2.2]
5508907  bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
116601151  bifunctional purine biosynthesis protein PURH-like [KO:K00602] [EC:2.1.2.3 3.5.4.10]
5504205  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
5516194  cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
5516196  cytosolic 5'-nucleotidase 1A isoform X1 [KO:K01081] [EC:3.1.3.5]
5519793  cytosolic purine 5'-nucleotidase isoform X2 [KO:K01081] [EC:3.1.3.5]
116614078  probable 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
116618173  trifunctional nucleotide phosphoesterase protein YfkN-like [KO:K01081] [EC:3.1.3.5]
5513868  snake venom 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
5512261  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
5496190  purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
5507551  laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
5504109  hypoxanthine-guanine phosphoribosyltransferase isoform X1 [KO:K00760] [EC:2.4.2.8]
5521993  inosine-5'-monophosphate dehydrogenase 1b [KO:K00088] [EC:1.1.1.205]
5522184  inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
5501312  nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
5509518  nucleoside diphosphate kinase III, chloroplastic/mitochondrial [KO:K00940] [EC:2.7.4.6]
5522240  nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
5505855  nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
5510276  LOW QUALITY PROTEIN: adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
116619730  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
5502159  soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
116603438  LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 4-like [KO:K12305] [EC:3.6.1.6]
116604452  ectonucleoside triphosphate diphosphohydrolase 5-like [KO:K01511] [EC:3.6.1.6]
5514401  nucleoside-diphosphatase mig-23 [KO:K01511] [EC:3.6.1.6]
5516494  U8 snoRNA-decapping enzyme [KO:K16855] [EC:3.6.1.62 3.6.1.64]
5516220  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
5502195  xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
5507602  xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
5503264  xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
5517059  LOW QUALITY PROTEIN: xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
5505020  xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
5505093  xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
5502066  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
5506184  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
116617007  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
5502773  GMP reductase 2 [KO:K00364] [EC:1.7.1.7]
5510346  guanine deaminase [KO:K01487] [EC:3.5.4.3]
5509058  MAGUK p55 subfamily member 6 [KO:K00942] [EC:2.7.4.8]
5522088  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
116619148  ribonucleoside-diphosphate reductase subunit M2-like isoform X1 [KO:K10808] [EC:1.17.4.1]
5513934  ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
5513935  ribonucleoside-diphosphate reductase subunit M2 B isoform X2 [KO:K10808] [EC:1.17.4.1]
5519397  HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
5510036  exopolyphosphatase PRUNE1 isoform X1 [KO:K01514] [EC:3.6.1.11]
5514741  adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
5517880  adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
5519173  adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
5502096  LOW QUALITY PROTEIN: uncharacterized protein LOC5502096 [KO:K11265] [EC:4.6.1.1]
5519178  guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
5519234  uncharacterized protein LOC5519234 [KO:K12319] [EC:4.6.1.2]
5519235  guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
5507622  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
5507623  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
5507631  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
5516962  atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
5517072  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
5497664  atrial natriuretic peptide receptor 2 [KO:K12323] [EC:4.6.1.2]
5498282  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
5501825  atrial natriuretic peptide receptor 1 [KO:K01769] [EC:4.6.1.2]
5515065  soluble guanylate cyclase 88E [KO:K01769] [EC:4.6.1.2]
5512057  soluble guanylate cyclase 89Db [KO:K01769] [EC:4.6.1.2]
5512066  soluble guanylate cyclase 88E [KO:K01769] [EC:4.6.1.2]
5508799  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform X1 [KO:K13755] [EC:3.1.4.17]
5510214  cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
5515693  cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
116620004  cGMP-inhibited 3',5'-cyclic phosphodiesterase A-like [KO:K19021] [EC:3.1.4.17]
5509007  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
5514591  cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13763] [EC:3.1.4.35]
5503186  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
5512668  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
5503074  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
5516632  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
5515594  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
5511171  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
5500638  adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
5503401  adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
5509958  AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
5515620  adenosine kinase isoform X2 [KO:K00856] [EC:2.7.1.20]
5517558  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
5501347  adenylate kinase 2, mitochondrial [KO:K00939] [EC:2.7.4.3]
5515204  LOW QUALITY PROTEIN: adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
5508024  adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
5510477  uncharacterized protein LOC5510477 [KO:K00939] [EC:2.7.4.3]
5503587  LOW QUALITY PROTEIN: adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
5514427  GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
5505665  cancer-related nucleoside-triphosphatase homolog isoform X1 [KO:K06928] [EC:3.6.1.15]
5507488  venom phosphodiesterase [KO:K01513] [EC:3.1.4.1 3.6.1.9]
5518224  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
5503136  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1 [KO:K18437] [EC:3.1.4.53]
5515726  bis(5'-adenosyl)-triphosphatase enpp4 isoform X1 [KO:K18424] [EC:3.6.1.29]
5519972  LOW QUALITY PROTEIN: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase [KO:K13811] [EC:2.7.7.4 2.7.1.25]
5502102  uricase isoform X2 [KO:K00365] [EC:1.7.3.3]
5515422  putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
5510212  putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
5521564  allantoinase, mitochondrial isoform X1 [KO:K01466] [EC:3.5.2.5]
5503786  allantoicase isoform X1 [KO:K01477] [EC:3.5.3.4]
5515206  urease subunit alpha [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
nve00030  Pentose phosphate pathway
nve00220  Arginine biosynthesis
nve00250  Alanine, aspartate and glutamate metabolism
nve00260  Glycine, serine and threonine metabolism
nve00340  Histidine metabolism
nve00630  Glyoxylate and dicarboxylate metabolism
nve00730  Thiamine metabolism
nve00740  Riboflavin metabolism
nve00790  Folate biosynthesis
KO pathway
ko00230   

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