KEGG   PATHWAY: rn00364
Entry
rn00364                     Pathway                                

Name
Fluorobenzoate degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
rn00364  Fluorobenzoate degradation
rn00364

Other DBs
UMBBD: 3fb 4fb box dcb
Reaction
R01033  2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)
R03932  4-chlorobenzoate:CoA ligase
R04101  4-Chlorobenzoyl CoA chlorohydrolase
R04349  3,5-dibromo-4-hydroxybenzonitrile aminohydrolase
R05276  4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)
R05451  2,4-dichlorobenzoate:CoA ligase
R07779  bromoxynil,NADPH:oxygen oxidoreductase
R07780  3,5-dibromo-4-hydroxybenzamide hydro-lyase (nitrile-forming)
R07781  2-maleylacetate:NAD+ oxidoreductase
R07782   
R07783   
R07784   
R07785   
R08100  2-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R08101  2-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R08103   
R08104   
R08105   
R08106   
R08108  3-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R08109  3-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R08110  4-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R08111  3-fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating)
R08112  5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating)
R08113  4-fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating)
R08114  3-fluorocatechol:oxygen 1,2-oxidoreductase
R08115  4-fluorocatechol:oxygen 1,2-oxidoreductase
R08116  4-fluoromuconolactone lyase (decyclizing)
R08117  4-fluorobenzoate:CoA ligase
R08118  4-fluorobenzoyl CoA fluorohydrolase
R08119  5-fluoromuconolactone lyase (decyclizing)
R08120  5-fluoromuconolactone lactonohydrolase
R08121  4-fluoromuconolactone lactonohydrolase
R08122   
R08123   
Compound
C00090  Catechol
C02222  2-Maleylacetate
C02357  2-Chlorobenzoate
C02359  2-Fluorobenzoate
C02364  3-Fluorobenzoate
C02370  4-Chlorobenzoate
C02371  4-Fluorobenzoate
C02802  4-Fluorobenzoyl-CoA
C02949  4-Hydroxybenzoyl-CoA
C03925  3,5-Dibromo-4-hydroxybenzoate
C04178  Bromoxynil
C06387  4-Chlorobenzoyl-CoA
C06670  2,4-Dichlorobenzoate
C06671  2,4-Dichlorobenzoyl-CoA
C11272  Fluorobenzene
C16246  3,5-Dibromo-4-hydroxybenzamide
C16247  2,6-Dibromophenol
C16248  2,6-Dibromohydroquinone
C16249  2-Bromomaleylacetate
C16472  3-Fluorocatechol
C16473  4-Fluorocatechol
C16474  3-Fluoro-cis,cis-muconate
C16475  2-Fluoro-cis,cis-muconate
C16476  4-Fluoromuconolactone
C16477  5-Fluoromuconolactone
C16478  3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate
C16479  5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate
C16480  4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate
C16481  6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate
C16482  2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate
C16483  4-Fluorocyclohexadiene-cis,cis-1,2-diol
C16484  1-Fluorocyclohexadiene-cis,cis-1,2-diol
Reference
  Authors
Schreiber A, Hellwig M, Dorn E, Reineke W, Knackmuss HJ.
  Title
Critical Reactions in Fluorobenzoic Acid Degradation by Pseudomonas sp. B13.
  Journal
Appl Environ Microbiol 39:58-67 (1980)
DOI:10.1128/AEM.39.1.58-67.1980
Reference
  Authors
Solyanikova IP, Moiseeva OV, Boeren S, Boersma MG, Kolomytseva MP, Vervoort J, Rietjens IM, Golovleva LA, van Berkel WJ.
  Title
Conversion of 2-fluoromuconate to cis-dienelactone by purified enzymes of Rhodococcus opacus 1cp.
  Journal
Appl Environ Microbiol 69:5636-42 (2003)
DOI:10.1128/AEM.69.9.5636-5642.2003
Reference
  Authors
Carvalho MF, Ferreira MI, Moreira IS, Castro PM, Janssen DB.
  Title
Degradation of fluorobenzene by Rhizobiales strain F11 via ortho cleavage of 4-fluorocatechol and catechol.
  Journal
Appl Environ Microbiol 72:7413-7 (2006)
DOI:10.1128/AEM.01162-06
Reference
  Authors
Chae JC, Song B, Zylstra GJ
  Title
Identification of genes coding for hydrolytic dehalogenation in the metagenome derived from a denitrifying 4-chlorobenzoate degrading consortium.
  Journal
FEMS Microbiol Lett 281:203-9 (2008)
DOI:10.1111/j.1574-6968.2008.01106.x
Reference
  Authors
Rosenbrock P, Munch JC, Scheunert I, Dorfler U.
  Title
Biodegradation of the herbicide bromoxynil and its plant cell wall bound residues in an agricultural soil.
  Journal
Pesticide Biochemistry and Physiology 78:49-57 (2004)
DOI:10.1016/j.pestbp.2003.09.002
Reference
PMID:1610174
  Authors
Topp E, Xun LY, Orser CS.
  Title
Biodegradation of the herbicide bromoxynil (3,5-dibromo-4-hydroxybenzonitrile) by purified pentachlorophenol hydroxylase and whole cells of Flavobacterium sp. strain ATCC 39723 is accompanied by cyanogenesis.
  Journal
Appl Environ Microbiol 58:502-6 (1992)
DOI:10.1128/AEM.58.2.502-506.1992
Related
pathway
rn00362  Benzoate degradation
rn00621  Dioxin degradation
KO pathway
ko00364   

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