KEGG   PATHWAY: rn00620
Entry
rn00620                     Pathway                                

Name
Pyruvate metabolism
Class
Metabolism; Carbohydrate metabolism
Pathway map
rn00620  Pyruvate metabolism
rn00620

Module
M00168  CAM (Crassulacean acid metabolism), dark [PATH:rn00620]
M00169  CAM (Crassulacean acid metabolism), light [PATH:rn00620]
M00172  C4-dicarboxylic acid cycle, NADP - malic enzyme type [PATH:rn00620]
M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:rn00620]
M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:rn00620]
Other DBs
GO: 0006090
Reaction
R00014  pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
R00196  (S)-Lactate:ferricytochrome-c 2-oxidoreductase
R00197  (R)-Lactate:ferricytochrome-c 2-oxidoreductase
R00198  (R)-Lactate:ferricytochrome-c-553 2-oxidoreductase
R00199  ATP:pyruvate,water phosphotransferase
R00200  ATP:pyruvate 2-O-phosphotransferase
R00203  pyruvaldehyde:NAD+ oxidoreductase
R00205  2-Oxopropanal:NADP+ oxidoreductase
R00206  ATP:pyruvate,phosphate phosphotransferase
R00207  Pyruvate:oxygen 2-oxidoreductase (phosphorylating)
R00211  pyruvate:oxygen 2-oxidoreductase (CoA-acetylating)
R00212  Acetyl-CoA:formate C-acetyltransferase
R00214  (S)-malate:NAD+ oxidoreductase (decarboxylating)
R00216  (S)-Malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating)
R00217  oxaloacetate carboxy-lyase (pyruvate-forming)
R00218  acetylenedicarboxylate carboxy-lyase (pyruvate-forming)
R00219  2-Hydroxyethylenedicarboxylate carboxy-lyase (pyruvate-forming)
R00227  Acetyl-CoA hydrolase
R00228  acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)
R00229  acetate:CoA ligase (ADP-forming)
R00230  acetyl-CoA:phosphate acetyltransferase
R00236  acetyl adenylate:CoA acetyltransferase
R00238  acetyl-CoA:acetyl-CoA C-acetyltransferase
R00271  acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
R00297  (R)-2-hydroxy-acid:acceptor 2-oxidoreductase
R00315  ATP:acetate phosphotransferase
R00316  ATP:acetate adenylyltransferase
R00317  Acetyl phosphate phosphohydrolase
R00319  (S)-lactate:oxygen 2-oxidoreductase (decarboxylating)
R00320  diphosphate:acetate phosphotransferase
R00326  acetaldehyde:acceptor oxidoreductase
R00341  ATP:oxaloacetate carboxy-lyase (transphosphorylating;phosphoenolpyruvate-forming)
R00342  (S)-malate:NAD+ oxidoreductase
R00343  (S)-malate:NADP+ oxidoreductase
R00344  Pyruvate:carbon-dioxide ligase (ADP-forming)
R00345  phosphate:oxaloacetate carboxy-lyase (adding phosphate;phosphoenolpyruvate-forming)
R00346  diphosphate:oxaloacetate carboxy-lyase (transphosphorylating;phosphoenolpyruvate-forming)
R00431  GTP:oxaloacetate carboxy-lyase (adding GTP;phosphoenolpyruvate-forming)
R00472  acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R00703  (S)-Lactate:NAD+ oxidoreductase
R00704  (R)-Lactate:NAD+ oxidoreductase
R00710  Acetaldehyde:NAD+ oxidoreductase
R00711  Acetaldehyde:NADP+ oxidoreductase
R00726  ITP:oxaloacetate carboxy-lyase (adding ITP; phosphoenolpyruvate-forming)
R00742  acetyl-CoA:carbon-dioxide ligase (ADP-forming)
R00746  Ethanol:NADP+ oxidoreductase
R00753  (S)-lactate acetaldehyde-lyase (formate-forming)
R00754  ethanol:NAD+ oxidoreductase
R00928  Acetyl-CoA:propanoate CoA-transferase
R00998  acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R01019  acetaldehyde:pyrroloquinoline-quinone oxidoreductase
R01082  (S)-malate hydro-lyase (fumarate-forming)
R01196  pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)
R01213  acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R01257  (S)-Malate:FAD oxidoreductase
R01446  (S)-lactaldehyde:NAD+ oxidoreductase
R01447  (S)-Lactate:oxaloacetate oxidoreductase
R01450  lactate racemase
R01735  (R)-Lactaldehyde:NAD+ 2-oxidoreductase
R01736  (R)-S-Lactoylglutathione hydrolase
R02164  succinate:quinone oxidoreductase
R02260  (S)-lactaldehyde:NADP+ oxidoreductase
R02320  NTP:pyruvate O2-phosphotransferase
R02527  (R)-Lactaldehyde:NAD+ oxidoreductase
R02530  (R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)
R02569  acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase
R03145  pyruvate:ubiquinone oxidoreductase
R03270   
R04177  2-Hydroxyethylenedicarboxylate hydro-lyase
R05063   
R05198  ethanol:cytochrome c oxidoreductase
R07618  enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
R09127  ethanol:cytochrome c oxidoreductase
R09479  ethanol:quinone oxidoreductase
R09796  (R)-lactate hydro-lyase
R10343  succinyl-CoA:acetate CoA-transferase
R10866  pyruvate:flavodoxin 2-oxidoreductase (CoA-acetylating)
R11074  (S)-malate carboxy-lyase
R11591  (R)-lactate:quinone 2-oxidoreductase
R11593  (R)-2-hydroxyglutarate:pyruvate oxidoreductase [(R)-lactate-forming]
R12212  oxaloacetate carboxy-lyase (pyruvate-forming; Na+-extruding)
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
rn00010  Glycolysis / Gluconeogenesis
rn00020  Citrate cycle (TCA cycle)
rn00061  Fatty acid biosynthesis
rn00072  Synthesis and degradation of ketone bodies
rn00260  Glycine, serine and threonine metabolism
rn00290  Valine, leucine and isoleucine biosynthesis
rn00300  Lysine biosynthesis
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
rn00630  Glyoxylate and dicarboxylate metabolism
rn00640  Propanoate metabolism
rn00650  Butanoate metabolism
rn00760  Nicotinate and nicotinamide metabolism
rn01056  Biosynthesis of type II polyketide backbone
rn01059  Biosynthesis of enediyne antibiotics
KO pathway
ko00620   

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