KEGG PATHWAY: rn00903

KEGG

PATHWAY: rn00903

Entry

rn00903 Pathway

Name

Limonene and pinene degradation

Class

Metabolism; Metabolism of terpenoids and polyketides

Pathway map

Limonene and pinene degradation

Reaction

(S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating)

(S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7-hydroxylating)

(-)-trans-Carveol:NADP+ oxidoreductase

Perillyl-alcohol:NAD+ oxidoreductase

alpha-Pinene-oxide lyase (decyclizing)

limonene-1,2-epoxide hydrolase

(+)-trans-carveol: NAD+ oxidoreductase

(R)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating)

Aldehyde:NAD+ oxidoreductase

perillic acid:CoA ligase (ADP-forming)

perillic acid:CoA ligase (AMP-forming)

2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA hydro-lyase

carvone reductase

carvone reductase

menth-8-en-2-ol:NAD+ oxidoreductase

menth-8-en-2-ol:NAD+ oxidoreductase

menth-8-en-2-ol:NAD+ oxidoreductase

menth-8-en-2-ol:NAD+ oxidoreductase

menth-8-en-2-ol:NAD+ oxidoreductase

menth-8-en-2-ol:NAD+ oxidoreductase

menth-8-en-2-ol:NAD+ oxidoreductase

menth-8-en-2-ol:NAD+ oxidoreductase

monocyclic monoterpene ketone monooxygenase

NADPH:oxygen oxidoreductase

NADPH:oxygen oxidoreductase

NADPH:oxygen oxidoreductase

monoterpene epsilon-lactone hydrolase

isopropenylmethyloxepan-2-one lactonohydrolase

4-isopropenyl-7-methyloxepan-2-one lactonohydrolase

monoterpene epsilon-lactone hydrolase

(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming)

limonene 1,2-monooxygenase

(1S,2S,4R)-menth-8-ene-1,2-diol:NAD+ 2-oxidoreductase

(1S,4R)-1-hydroxymenth-8-en-2-one,NADPH:oxygen oxidoreductase

alpha-Pinene dehydrogenase

Myrtenol dehydrogenase

Myrtenal dehydrogenase

alpha-pinene monooxygenase

Pinocarveol dehydrogenase

alpha-Pinene monooxygenase

cis-2-Methyl-5-isopropylhexa-2,5-dienal dehydrogenase

trans-2-Methyl-5-isopropylhexa-2,5-dienal dehydrogenase

cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase

trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase

3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA hydro-lyase

trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase

3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase

2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase

3-Isopropylbut-3-enoyl-CoA thioesterase

(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming)

(S)-limonene,NADH:oxygen oxidoreductase

limonene-1,2-epoxide hydrolase

(1R,2R,4S)-menth-8-ene-1,2-diol:NAD+ 2-oxidoreductase

(S)-limonene,NADPH:oxygen oxidoreductase

(1R,4S)-1-hydroxymenth-8-en-2-one,NADPH:oxygen oxidoreductase

limonene,NADPH:oxygen oxidoreductase

Compound

(S)-Limonene

(-)-trans-Carveol

(-)-Carvone

(-)-Perillyl alcohol

Perillyl aldehyde

alpha-Pinene-oxide

(Z)-2-Methyl-5-isopropylhexa-2,5-dienal

(R)-Limonene

Limonene-1,2-epoxide

Limonene-1,2-diol

alpha-Pinene

Pinocarvone

(+)-(S)-Carvone

(4R,6R)-cis-Carveol

(1R,2R,4R)-Dihydrocarveol

(1R,2S,4R)-Neo-dihydrocarveol

(1R,4R)-Dihydrocarvone

(1S,2S,4R)-Iso-dihydrocarveol

(1S,2R,4R)-Neoiso-dihydrocarveol

(1S,4R)-Iso-dihydrocarvone

(4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone

(3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone

(3R)-6-Hydroxy-3-isopropenyl-heptanoate

(3R)-3-Isopropenyl-6-oxoheptanoate

(5R)-6-Hydroxy-5-isopropenyl-2-methylhexanoate

(3R)-3-Isopropenyl-6-oxoheptanoyl-CoA

(4S,6S)-cis-Carveol

(+)-trans-Carveol

(1R,2S,4S)-Neoiso-dihydrocarveol

(1R,2R,4S)-Iso-dihydrocarveol

(1R,4S)-Iso-dihydrocarvone

(1S,2S,4S)-Dihydrocarveol

(4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone

(1S,4S)-Dihydrocarvone

(1S,2R,4S)-Neo-dihydrocarveol

(3S)-6-Hydroxy-3-isopropenyl-heptanoate

(3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone

(3S)-3-Isopropenyl-6-oxoheptanoate

(5S)-6-Hydroxy-5-isopropenyl-2-methylhexanoate

(3S)-3-Isopropenyl-6-oxoheptanoyl-CoA

Perillic acid

Perillyl-CoA

2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA

4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA

3-Isopropenylpimelyl-CoA

(1S,4R)-1-Hydroxy-2-oxolimonene

Myrtenol

Myrtenal

Myrtenic acid

Pinocarveol

trans-2-Methyl-5-isopropylhexa-2,5-dienal

trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid

cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid

trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA

cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA

3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA

2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA

3-Isopropylbut-3-enoyl-CoA

3-Isopropyl-3-butenoic acid

(4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone

(4S)-Limonene-1,2-epoxide

(1R,2R,4S)-Limonene-1,2-diol

(1R,4S)-1-Hydroxy-2-oxolimonene

(4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone

Reference

Authors

van der Werf MJ, Swarts HJ, de Bont JA

Title

Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene.

Journal

Appl Environ Microbiol 65:2092-102 (1999)
DOI:10.1128/AEM.65.5.2092-2102.1999

Reference

Authors

van der Werf MJ, Boot AM

Title

Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14.

Journal

Microbiology 146 ( Pt 5):1129-41 (2000)
DOI:10.1099/00221287-146-5-1129

Related
pathway

Monoterpenoid biosynthesis

KO pathway

All links

Chemical reaction (98)   
   KEGG REACTION (67)   
   KEGG RCLASS (31)   
All databases (98)   

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