KEGG   PATHWAY: thi00630
Entry
thi00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thiomonas arsenitoxydans
Class
Metabolism; Carbohydrate metabolism
Pathway map
thi00630  Glyoxylate and dicarboxylate metabolism
thi00630

Module
thi_M00012  Glyoxylate cycle [PATH:thi00630]
thi_M00621  Glycine cleavage system [PATH:thi00630]
Other DBs
GO: 0046487 0043648
Organism
Thiomonas arsenitoxydans [GN:thi]
Gene
THI_1747  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
THI_1197  putative Acetate--coa ligase [KO:K01895] [EC:6.2.1.1]
THI_2397  acsA; Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme) [KO:K01895] [EC:6.2.1.1]
THI_3344  aceB; Malate synthase A (MSA) [KO:K01638] [EC:2.3.3.9]
THI_2717  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
THI_2710  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
THI_2722  acnA; Aconitate hydratase 1 (Citrate hydro-lyase 1) (Aconitase 1) [KO:K01681] [EC:4.2.1.3]
THI_1641  phbA1; acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase) [KO:K00626] [EC:2.3.1.9]
THI_3278  phbA2; acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase) [KO:K00626] [EC:2.3.1.9]
THI_1642  phbB1; 3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00023] [EC:1.1.1.36]
THI_0783  glcD; Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
THI_0782  glcE; Glycolate oxidase subunit glcE [KO:K11472] [EC:1.1.99.14]
THI_0781  glcF; Glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
THI_3266  Putative 2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
THI_0570  putative glyoxylate reductase (Glycolate reductase) [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
THI_0161  cbbZ; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
THI_2794  putative phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
THI_3735  putative Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
THI_0135  rbcL; Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (RuBisCO large subunit) [KO:K01601] [EC:4.1.1.39]
THI_2041  cbbM; Ribulose bisphosphate carboxylase (RuBisCO) [KO:K01601] [EC:4.1.1.39]
THI_0136  cbbS; Ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit (RubisCO) [KO:K01602] [EC:4.1.1.39]
THI_0200  putative glutamine synthetase (GS) [KO:K01915] [EC:6.3.1.2]
THI_0910  glyA; Serine hydroxymethyltransferase (Serine methylase) (SHMT) [KO:K00600] [EC:2.1.2.1]
THI_2972  gcvP; Glycine dehydrogenase [decarboxylating] (Glycine decarboxylase) (Glycine cleavage system P-protein) [KO:K00281] [EC:1.4.4.2]
THI_2974  putative Aminomethyltransferase (Glycine cleavage system T protein) GcvT [KO:K00605] [EC:2.1.2.10]
THI_0061  putative Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
THI_2235  putative Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
THI_2678  lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein) [KO:K00382] [EC:1.8.1.4]
THI_1673  odhL; Dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex) (Dihydrolipoamide dehydrogenase) [KO:K00382] [EC:1.8.1.4]
THI_2973  gcvH; Glycine cleavage system H protein [KO:K02437]
THI_3412  gcl; glyoxylate carboligase (Tartronate-semialdehyde synthase) [KO:K01608] [EC:4.1.1.47]
THI_3411  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
THI_3410  glxR; 2-hydroxy-3-oxopropionate reductase (Tartronate semialdehyde reductase) (TSAR) [KO:K00042] [EC:1.1.1.60]
THI_2729  putative 2-hydroxy-3-oxopropionate reductase (Tartronate semialdehyde reductase) (TSAR), garR [KO:K00042] [EC:1.1.1.60]
THI_3409  putative hydroxypyruvate reductase ttuD [KO:K11529] [EC:2.7.1.165]
THI_1422  Tartrate dehydrogenase/decarboxylase (TDH) (D-malate dehydrogenase [decarboxylating]) [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
THI_0009  eda; KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxy-phosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase) (Phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)] [KO:K01625] [EC:4.1.2.14 4.1.3.42]
THI_0005  fdwA; Tungsten-containing formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
THI_3511  fdhA; Formate dehydrogenase, alpha subunit FdnA [KO:K00123] [EC:1.17.1.9]
THI_0004  fdwB; Tungsten-containing formate dehydrogenase beta subunit [KO:K22515] [EC:1.17.1.9]
THI_3510  fdhB; formate dehydrogenase iron-sulfur subunit [KO:K00124]
THI_3508  fdoI; formate dehydrogenase gamma subunit [KO:K00127]
THI_2730  conserved hypothetical protein [KO:K01432] [EC:3.5.1.9]
THI_3648  putative esterase/lipase [KO:K01432] [EC:3.5.1.9]
THI_1259  putative cyclase [KO:K07130] [EC:3.5.1.9]
THI_0542  putative formyltetrahydrofolate deformylase PurU [KO:K01433] [EC:3.5.1.10]
THI_3634  amiF; Formamidase (Formamide amidohydrolase) [KO:K01455] [EC:3.5.1.49]
THI_0810  putative N-formylglutamate deformylase hutG [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
thi00010  Glycolysis / Gluconeogenesis
thi00020  Citrate cycle (TCA cycle)
thi00030  Pentose phosphate pathway
thi00071  Fatty acid degradation
thi00230  Purine metabolism
thi00250  Alanine, aspartate and glutamate metabolism
thi00260  Glycine, serine and threonine metabolism
thi00620  Pyruvate metabolism
thi00710  Carbon fixation in photosynthetic organisms
thi00750  Vitamin B6 metabolism
thi00910  Nitrogen metabolism
KO pathway
ko00630   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (48)   
   KEGG GENES (48)   
All databases (49)   

Download RDF
DBGET integrated database retrieval system