PATHWAY: emu02010 Help
Entry
Name
ABC transporters - Enterococcus mundtii
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Enterococcus mundtii [GN:
emu ]
Gene
EMQU_2099 spermidine/putrescine ABC transporter substrate-binding protein [KO:K11069 ]
EMQU_2100 potC; spermidine/putrescine ABC superfamily ATP binding cassette transporter, membrane protein [KO:K11070 ]
EMQU_2101 potB; spermidine/putrescine ABC superfamily ATP binding cassette transporter, membrane protein [KO:K11071 ]
EMQU_2442 proWX; glycine betaine/carnitine/choline ABC superfamily ATP binding cassette transporter, membrane/binding protein [KO:K02001 K02002 ]
EMQU_0216 opuCC; glycine/betaine/carnitine/choline ABC superfamily ATP binding cassette transporter, binding protein [KO:K05845 ]
EMQU_0215 opuCD; glycine/betaine/carnitine/choline ABC superfamily ATP binding cassette transporter, membrane protein [KO:K05846 ]
EMQU_0217 opuCB; glycine/betaine/carnitine/choline ABC superfamily ATP binding cassette transporter, membrane protein [KO:K05846 ]
EMQU_0218 opuAA; glycine/betaine/carnitine/choline ABC superfamily ATP binding cassette transporter, ABC protein [KO:K05847 ] [EC:7.6.2.9 ]
EMQU_1473 ABC superfamily ATP binding cassette transporter, ABC protein [KO:K10112 ] [EC:7.5.2.-]
EMQU_0635 sugar ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
EMQU_1434 malX; maltose/maltodextrin ABC superfamily ATP binding cassette transporter, binding protein [KO:K15770 ]
EMQU_1433 malC; maltose/maltodextrin ABC superfamily ATP binding cassette transporter, membrane protein [KO:K15771 ]
EMQU_1582 lactose ABC superfamily ATP binding cassette transporter, binding protein [KO:K10188 ]
EMQU_1581 lacF2; lactose ABC superfamily ATP binding cassette transporter, membrane protein [KO:K10189 ]
EMQU_1580 lacG2; lactose ABC superfamily ATP binding cassette transporter, membrane protein [KO:K10190 ]
EMQU_2671 multiple sugar ABC transporter substrate-binding protein [KO:K17318 ]
EMQU_2672 ypcH; carbohydrate ABC superfamily ATP binding cassette transporter, membrane protein [KO:K17320 ]
EMQU_1845 sugar ABC superfamily ATP binding cassette transporter, binding protein [KO:K10546 ]
EMQU_1843 araH; L-arabinose ABC superfamily ATP binding cassette transporter, membrane protein [KO:K10547 ]
EMQU_1844 araG; L-arabinose ABC superfamily ATP binding cassette transporter, ABC protein [KO:K10548 ] [EC:7.5.2.-]
EMQU_2808 araG; L-arabinose ABC superfamily ATP binding cassette transporter, ABC protein [KO:K10441 ] [EC:7.5.2.7 ]
EMQU_1846 ABC superfamily ATP binding cassette transporter, binding protein [KO:K23508 ]
EMQU_1962 pstC; phosphate ABC superfamily ATP binding cassette transporter, membrane protein [KO:K02037 ]
EMQU_1961 pstA; phosphate ABC superfamily ATP binding cassette transporter, membrane protein [KO:K02038 ]
EMQU_1960 pstB2; phosphate ABC superfamily ATP binding cassette transporter, ABC protein [KO:K02036 ] [EC:7.3.2.1 ]
EMQU_2194 phnE; phosphonate ABC transporter, permease protein PhnE [KO:K02042 ]
EMQU_1252 glnC; glutamate ABC superfamily ATP binding cassette transporter, membrane protein [KO:K10040 ]
EMQU_1250 glnQ; glutamate ABC superfamily ATP binding cassette transporter, ABC protein [KO:K10041 ] [EC:7.4.2.1 ]
EMQU_0176 amino acid ABC superfamily ATP binding cassettetransporter, ABC protein [KO:K17076 ]
EMQU_2314 metal ion ABC superfamily ATP binding cassette transporter, binding protein [KO:K02073 ]
EMQU_2155 metI; D-methionine ABC superfamily ATP binding cassette transporter, membrane protein [KO:K02072 ]
EMQU_2315 metal ion ABC superfamily ATP binding cassette transporter, membrane protein [KO:K02072 ]
EMQU_2156 metN; D-methionine ABC superfamily ATP binding cassette transporter, ABC protein [KO:K02071 ]
EMQU_0618 dppB; oligopeptide ABC superfamily ATP binding cassette transporter, membrane protein [KO:K15581 ]
EMQU_0621 dppF; oligopeptide ABC superfamily ATP binding cassette transporter, ABC protein [KO:K10823 ]
EMQU_0559 psaA; manganese ABC superfamily ATP binding cassette transporter, binding protein [KO:K19975 ]
EMQU_2741 adcB; zinc ABC superfamily ATP binding cassette transporter, membrane protein [KO:K09816 ]
EMQU_0112 cobalt ABC superfamily ATP binding cassette transporter, ABC protein [KO:K16786 ] [EC:7.-.-.-]
EMQU_0113 cbiO2; cobalt transporter ATP-binding subunit [KO:K16787 ] [EC:7.-.-.-]
EMQU_0901 tagH; teichoic acid ABC superfamily ATP binding cassette transporter, ABC protein [KO:K09693 ] [EC:7.5.2.4 ]
EMQU_0741 ABC superfamily ATP binding cassette transporter, membrane protein [KO:K11632 ]
EMQU_1966 ftsE; ABC superfamily ATP binding cassette transporter, ABC protein [KO:K09812 ]
EMQU_1932 mdlB; multidrug ABC superfamily ATP binding cassette transporter, ABC/membrane protein [KO:K18890 ]
EMQU_2690 ABC superfamily ATP binding cassette transporter, membrane protein [KO:K18891 ]
EMQU_2388 lmrA; multidrug resistance ABC superfamily ATP binding cassette transporter, ABC/membrane protein [KO:K18887 ]
EMQU_1592 ABC superfamily ATP binding cassette transporter, membrane protein [KO:K18888 ]
EMQU_2574 ABC superfamily ATP binding cassette transporter, ABC protein [KO:K18231 ]
EMQU_2147 ABC superfamily ATP binding cassette transporter, ABC protein [KO:K19350 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway