KEGG   PATHWAY: ldo00280
Entry
ldo00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Leishmania donovani
Class
Metabolism; Amino acid metabolism
Pathway map
ldo00280  Valine, leucine and isoleucine degradation
ldo00280

Module
ldo_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ldo00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Leishmania donovani [GN:ldo]
Gene
LDBPK_271950  branched-chain amino acid aminotransferase, putative [KO:K00826] [EC:2.6.1.42]
LDBPK_211670  2-oxoisovalerate dehydrogenase alpha subunit, putative [KO:K00166] [EC:1.2.4.4]
LDBPK_350050  2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor, putative [KO:K00167] [EC:1.2.4.4]
LDBPK_050180  dihydrolipoamide branched chain transacylase, putative [KO:K09699] [EC:2.3.1.168]
LDBPK_323510  dihydrolipoamide dehydrogenase, putative [KO:K00382] [EC:1.8.1.4]
LDBPK_312710  2-oxoglutarate dehydrogenase, E3 component, lipoamidedehydrogenase-like protein [KO:K00382] [EC:1.8.1.4]
LDBPK_312720  acetoin dehydrogenase E3 component-like protein [KO:K00382] [EC:1.8.1.4]
LDBPK_291950  dihydrolipoamide dehydrogenase, putative [KO:K00382] [EC:1.8.1.4]
LDBPK_060910  acyl-coenzyme a dehydrogenase, putative [KO:K00249] [EC:1.3.8.7]
LDBPK_270790  isovaleryl-coA dehydrogenase, putative [KO:K00253] [EC:1.3.8.4]
LDBPK_352780  acyl-CoA dehydrogenase, putative [KO:K09478] [EC:1.3.8.5]
LDBPK_292420  enoyl-CoA hydratase/isomerase-like protein [KO:K07511] [EC:4.2.1.17]
LDBPK_361200  short chain 3-hydroxyacyl-CoA dehydrogenase, putative [KO:K00022] [EC:1.1.1.35]
LDBPK_230860  3-ketoacyl-CoA thiolase-like protein [KO:K00632] [EC:2.3.1.16]
LDBPK_010050  carboxylase, putative [KO:K01965] [EC:6.4.1.3]
LDBPK_280260  propionyl-coa carboxylase beta chain, putative [KO:K01966] [EC:6.4.1.3 2.1.3.15]
LDBPK_280250  propionyl-coa carboxylase beta chain, putative [KO:K01966] [EC:6.4.1.3 2.1.3.15]
LDBPK_260030  methylmalonyl-coa epimerase-like protein [KO:K05606] [EC:5.1.99.1]
LDBPK_270310  methylmalonyl-coenzyme a mutase, putative [KO:K01847] [EC:5.4.99.2]
LDBPK_323830  enoyl-CoA hydratase/isomerase family protein, putative [KO:K05605] [EC:3.1.2.4]
LDBPK_323820  3-hydroxyisobutyryl-coenzyme a hydrolase-like protein [KO:K05605] [EC:3.1.2.4]
LDBPK_251160  aldehyde dehydrogenase, mitochondrial precursor [KO:K00128] [EC:1.2.1.3]
LDBPK_313260  methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein [KO:K01968] [EC:6.4.1.4]
LDBPK_110600  3-methylcrotonoyl-CoA carboxylase beta subunit, putative [KO:K01969] [EC:6.4.1.4]
LDBPK_350360  enoyl-CoA hydratase/isomerase family protein, conserved [KO:K05607] [EC:4.2.1.18]
LDBPK_332470  succinyl-coA:3-ketoacid-coenzyme A transferase, mitochondrial precursor, putative [KO:K01027] [EC:2.8.3.5]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
ldo00020  Citrate cycle (TCA cycle)
ldo00240  Pyrimidine metabolism
ldo00290  Valine, leucine and isoleucine biosynthesis
ldo00640  Propanoate metabolism
ldo00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG GENES (26)   
All databases (27)   

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