KEGG   PATHWAY: mle00280
Entry
mle00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Mycobacterium leprae TN
Class
Metabolism; Amino acid metabolism
Pathway map
mle00280  Valine, leucine and isoleucine degradation
mle00280

Module
mle_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mle00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Mycobacterium leprae TN [GN:mle]
Gene
ML0866  ilvE; putative branched-chain-amino-acid transaminase [KO:K00826] [EC:2.6.1.42]
ML2387  lpd; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
ML0660  fadE23; putative acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
ML2402  putative enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
ML1241  possible enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
ML1724  putative enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
ML2161  fadB; putative fatty oxidation complex alpha subunit [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
ML0726  bccA; acetyl/propionyl CoA carboxylase [alpha] subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
ML1657  acetyl/propionyl CoA carboxylase [beta] subunit [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
ML1157  conserved hypothetical protein [KO:K05606] [EC:5.1.99.1]
ML1799  mutB; methylmalonyl-CoA mutase, [alpha] subunit [KO:K01847] [EC:5.4.99.2]
ML1800  mutA; methylmalonyl-CoA mutase, [beta] subunit [KO:K01847] [EC:5.4.99.2]
ML2639  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
ML0485  gabT; putative 4-aminobutyrate aminotransferase [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
ML1158  fadA4; possible acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
ML2162  fadA; putative beta-ketoadipyl CoA thiolase [KO:K00626] [EC:2.3.1.9]
ML2564  fadA2; acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
mle00020  Citrate cycle (TCA cycle)
mle00240  Pyrimidine metabolism
mle00290  Valine, leucine and isoleucine biosynthesis
mle00640  Propanoate metabolism
mle00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG GENES (17)   
All databases (18)   

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