KEGG   PATHWAY: nca00280
Entry
nca00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Nocardioides sp. JS614
Class
Metabolism; Amino acid metabolism
Pathway map
nca00280  Valine, leucine and isoleucine degradation
nca00280

Module
nca_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nca00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Nocardioides sp. JS614 [GN:nca]
Gene
Noca_3367  branched chain amino acid aminotransferase apoenzyme [KO:K00826] [EC:2.6.1.42]
Noca_2367  aminotransferase, class IV [KO:K00826] [EC:2.6.1.42]
Noca_4313  valine dehydrogenase (NAD) [KO:K00271] [EC:1.4.1.23]
Noca_4509  Pyruvate dehydrogenase (acetyl-transferring) [KO:K00166] [EC:1.2.4.4]
Noca_4508  Transketolase, central region [KO:K00167] [EC:1.2.4.4]
Noca_4454  dehydrogenase, E1 component [KO:K11381] [EC:1.2.4.4]
Noca_4507  catalytic domain of components of various dehydrogenase complexes [KO:K09699] [EC:2.3.1.168]
Noca_3518  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Noca_2304  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Noca_4554  acyl-CoA dehydrogenase domain protein [KO:K00249] [EC:1.3.8.7]
Noca_1832  acyl-CoA dehydrogenase domain protein [KO:K00249] [EC:1.3.8.7]
Noca_0046  acyl-CoA dehydrogenase domain protein [KO:K00249] [EC:1.3.8.7]
Noca_2604  acyl-CoA dehydrogenase domain protein [KO:K00249] [EC:1.3.8.7]
Noca_4130  acyl-CoA dehydrogenase domain protein [KO:K00249] [EC:1.3.8.7]
Noca_3866  acyl-CoA dehydrogenase domain protein [KO:K00249] [EC:1.3.8.7]
Noca_3506  butyryl-CoA dehydrogenase [KO:K11410] [EC:1.3.8.5]
Noca_1813  short chain enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
Noca_1521  short chain enoyl-CoA hydratase / Enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
Noca_4562  3-hydroxyacyl-CoA dehydrogenase [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
Noca_2853  acetyl-CoA acetyltransferase [KO:K00632] [EC:2.3.1.16]
Noca_4551  Carbamoyl-phosphate synthase L chain, ATP-binding protein [KO:K01965] [EC:6.4.1.3]
Noca_3495  propionyl-CoA carboxylase carboxyltransferase subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Noca_3510  biotin carboxylase / biotin carboxyl carrier protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Noca_0148  Carbamoyl-phosphate synthase L chain, ATP-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Noca_1986  Propionyl-CoA carboxylase [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Noca_1796  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Noca_3544  heterodimeric methylmalonyl-CoA mutase large subunit precursor [KO:K01847] [EC:5.4.99.2]
Noca_3545  heterodimeric methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
Noca_0799  cobalamin B12-binding domain protein [KO:K01849] [EC:5.4.99.2]
Noca_0798  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Noca_2159  3-hydroxyisobutyrate dehydrogenase [KO:K00020] [EC:1.1.1.31]
Noca_4475  6-phosphogluconate dehydrogenase, NAD-binding protein [KO:K00020] [EC:1.1.1.31]
Noca_4626  methylmalonate-semialdehyde dehydrogenase (acylating) [KO:K00140] [EC:1.2.1.18 1.2.1.27]
Noca_3634  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
Noca_3529  aldehyde dehydrogenase (acceptor) [KO:K00128] [EC:1.2.1.3]
Noca_0645  4-aminobutyrate aminotransferase apoenzyme [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
Noca_3205  4-aminobutyrate aminotransferase apoenzyme [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
Noca_0147  Propionyl-CoA carboxylase [KO:K01969] [EC:6.4.1.4]
Noca_0149  hydroxymethylglutaryl-CoA lyase [KO:K01640] [EC:4.1.3.4]
Noca_0330  3-oxoacid CoA-transferase, A subunit [KO:K01028] [EC:2.8.3.5]
Noca_0331  butyryl-CoA:acetate CoA transferase [KO:K01029] [EC:2.8.3.5]
Noca_1371  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_1797  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_1828  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_4142  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_2734  peptidase M22, glycoprotease [KO:K00626] [EC:2.3.1.9]
Noca_2740  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_2764  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_2847  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Noca_4563  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
nca00020  Citrate cycle (TCA cycle)
nca00240  Pyrimidine metabolism
nca00290  Valine, leucine and isoleucine biosynthesis
nca00640  Propanoate metabolism
nca00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (50)   
   KEGG GENES (50)   
All databases (51)   

Download RDF
DBGET integrated database retrieval system