KEGG   PATHWAY: nca00620
Entry
nca00620                    Pathway                                
Name
Pyruvate metabolism - Nocardioides sp. JS614
Class
Metabolism; Carbohydrate metabolism
Pathway map
nca00620  Pyruvate metabolism
nca00620

Module
nca_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:nca00620]
nca_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:nca00620]
Other DBs
GO: 0006090
Organism
Nocardioides sp. JS614 [GN:nca]
Gene
Noca_0860  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Noca_0346  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Noca_2360  pyruvate ferredoxin oxidoreductase, alpha subunit [KO:K00169] [EC:1.2.7.1]
Noca_2359  pyruvate ferredoxin oxidoreductase, beta subunit [KO:K00170] [EC:1.2.7.1]
Noca_2361  pyruvate ferredoxin oxidoreductase, gamma subunit [KO:K00172] [EC:1.2.7.1]
Noca_0537  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00174] [EC:1.2.7.3 1.2.7.11]
Noca_0536  thiamine pyrophosphate enzyme domain protein TPP-binding protein [KO:K00175] [EC:1.2.7.3 1.2.7.11]
Noca_4858  2-oxo-acid dehydrogenase E1 subunit, homodimeric type [KO:K00163] [EC:1.2.4.1]
Noca_1993  2-oxo-acid dehydrogenase E1 subunit, homodimeric type [KO:K00163] [EC:1.2.4.1]
Noca_2105  2-oxo-acid dehydrogenase E1 component homodimeric type [KO:K00163] [EC:1.2.4.1]
Noca_4453  catalytic domain of components of various dehydrogenase complexes [KO:K00627] [EC:2.3.1.12]
Noca_2303  2-oxoglutarate dehydrogenase E2 component [KO:K00627] [EC:2.3.1.12]
Noca_3518  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Noca_2304  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Noca_1650  acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
Noca_2150  acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
Noca_2363  Alcohol dehydrogenase GroES domain protein [KO:K13953] [EC:1.1.1.1]
Noca_3322  Alcohol dehydrogenase GroES domain protein [KO:K13953] [EC:1.1.1.1]
Noca_2953  acetate kinase [KO:K00925] [EC:2.7.2.1]
Noca_2954  phosphotransacetylase [KO:K13788] [EC:2.3.1.8]
Noca_3020  pyruvate kinase [KO:K00873] [EC:2.7.1.40]
Noca_4108  biotin/lipoyl attachment domain-containing protein [KO:K02160]
Noca_0185  biotin/lipoyl attachment domain-containing protein [KO:K02160]
Noca_3510  biotin carboxylase / biotin carboxyl carrier protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Noca_0148  Carbamoyl-phosphate synthase L chain, ATP-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Noca_1986  Propionyl-CoA carboxylase [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Noca_4339  acylphosphatase [KO:K01512] [EC:3.6.1.7]
Noca_3634  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
Noca_3529  aldehyde dehydrogenase (acceptor) [KO:K00128] [EC:1.2.1.3]
Noca_2092  Aldehyde dehydrogenase (NAD(+)) [KO:K00138] [EC:1.2.1.-]
Noca_4811  CoA-binding domain protein [KO:K24012] [EC:6.2.1.13]
Noca_4844  CoA-binding domain protein [KO:K24012] [EC:6.2.1.13]
Noca_0280  (S)-2-hydroxy-acid oxidase [KO:K00101] [EC:1.1.2.3]
Noca_4175  thiamine pyrophosphate enzyme TPP binding domain protein [KO:K00156] [EC:1.2.5.1]
Noca_2396  beta-lactamase domain protein [KO:K01069] [EC:3.1.2.6]
Noca_2937  beta-lactamase domain protein [KO:K01069] [EC:3.1.2.6]
Noca_2000  conserved hypothetical protein [KO:K22373] [EC:5.1.2.1]
Noca_0113  Malate dehydrogenase (oxaloacetate-decarboxylating) [KO:K00027] [EC:1.1.1.38]
Noca_1727  Malate dehydrogenase (oxaloacetate-decarboxylating) [KO:K00027] [EC:1.1.1.38]
Noca_2034  Malate dehydrogenase (oxaloacetate-decarboxylating) [KO:K00027] [EC:1.1.1.38]
Noca_3513  pyruvate carboxylase [KO:K01958] [EC:6.4.1.1]
Noca_3578  malate dehydrogenase (NAD) [KO:K00024] [EC:1.1.1.37]
Noca_1061  fumarase [KO:K01676] [EC:4.2.1.2]
Noca_1059  fumarase [KO:K01679] [EC:4.2.1.2]
Noca_0190  Phosphoenolpyruvate carboxykinase (GTP) [KO:K01596] [EC:4.1.1.32]
Noca_4168  Phosphoenolpyruvate carboxykinase (GTP) [KO:K01596] [EC:4.1.1.32]
Noca_4472  Phosphoenolpyruvate carboxykinase (GTP) [KO:K01596] [EC:4.1.1.32]
Noca_0987  pyruvate phosphate dikinase [KO:K01006] [EC:2.7.9.1]
Noca_1185  Pyruvate, water dikinase [KO:K01007] [EC:2.7.9.2]
Noca_1184  PEP-utilizing enzyme, mobile region [KO:K01007] [EC:2.7.9.2]
Noca_1371  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_1797  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_1828  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_4142  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_2734  peptidase M22, glycoprotease [KO:K00626] [EC:2.3.1.9]
Noca_2740  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_2764  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_2847  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Noca_4563  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Noca_1927  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Noca_3364  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
nca00010  Glycolysis / Gluconeogenesis
nca00020  Citrate cycle (TCA cycle)
nca00061  Fatty acid biosynthesis
nca00250  Alanine, aspartate and glutamate metabolism
nca00260  Glycine, serine and threonine metabolism
nca00290  Valine, leucine and isoleucine biosynthesis
nca00300  Lysine biosynthesis
nca00630  Glyoxylate and dicarboxylate metabolism
nca00640  Propanoate metabolism
nca00650  Butanoate metabolism
nca00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (61)   
   KEGG GENES (61)   
All databases (62)   

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