KEGG   PATHWAY: pae00564Help
Entry
pae00564                    Pathway                                

Name
Glycerophospholipid metabolism - Pseudomonas aeruginosa PAO1
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
pae00564  Glycerophospholipid metabolism
pae00564

Ortholog table
Module
pae_M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:pae00564]
Other DBs
GO: 0006650 0046474 0046475
Organism
Pseudomonas aeruginosa PAO1 [GN:pae]
Gene
PA1614  gpsA; glycerol-3-phosphate dehydrogenase [KO:K00057] [EC:1.1.1.94]
PA3584  glpD; glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
PA3025  FAD-dependent glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
PA3673  plsB; glycerol-3-phosphate acyltransferase [KO:K00631] [EC:2.3.1.15]
PA0581  glycerol-3-phosphate acyltransferase PlsY [KO:K08591] [EC:2.3.1.275]
PA0005  lptA; lysophosphatidic acid acyltransferase [KO:K00655] [EC:2.3.1.51]
PA3603  dgkA; diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]
PA0844  plcH; hemolytic phospholipase C [KO:K01114] [EC:3.1.4.3]
PA3319  plcN; non-hemolytic phospholipase C [KO:K01114] [EC:3.1.4.3]
PA0347  glpQ; glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
PA2352  glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
PA2990  phosphodiesterase [KO:K01126] [EC:3.1.4.46]
PA4792  hypothetical protein [KO:K01126] [EC:3.1.4.46]
PA4024  eutB; ethanolamine ammonia-lyase large subunit [KO:K03735] [EC:4.3.1.7]
PA4025  ethanolamine ammonia-lyase small subunit [KO:K03736] [EC:4.3.1.7]
PA2536  phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
PA3651  cdsA; phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
PA3857  pcs; phosphatidylcholine synthase [KO:K01004] [EC:2.7.8.24]
PA4693  pssA; phosphatidylserine synthase [KO:K17103] [EC:2.7.8.8]
PA4957  psd; phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]
PA2541  CDP-alcohol phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]
PA2584  pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]
PA4050  pgpA; phosphatidylglycerophosphatase A [KO:K01095] [EC:3.1.3.27]
PA5394  cls; cardiolipin synthetase [KO:K06131] [EC:2.7.8.-]
PA2155  cardiolipin synthase 2 [KO:K06131] [EC:2.7.8.-]
PA5310  hypothetical protein [KO:K06132] [EC:2.7.8.-]
Compound
C00040  Acyl-CoA
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-O-(geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
KO pathway
ko00564   

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