KEGG   PATHWAY: sma00564
Entry
sma00564                    Pathway                                
Name
Glycerophospholipid metabolism - Streptomyces avermitilis
Class
Metabolism; Lipid metabolism
Pathway map
sma00564  Glycerophospholipid metabolism
sma00564

Module
sma_M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sma00564]
Other DBs
GO: 0006650
Organism
Streptomyces avermitilis [GN:sma]
Gene
SAVERM_2680  gpsA; putative glycerol-3-phosphate dehydrogenase, NAD(P)H-dependent [KO:K00057] [EC:1.1.1.94]
SAVERM_6663  glpD1; putative glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
SAVERM_5003  glpD2; putative glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
SAVERM_7111  plsC6; putative 1-acylglycerol-3-phosphate O-acyltransferase [KO:K00655] [EC:2.3.1.51]
SAVERM_6080  plsC3; putative 1-acylglycerol-3-phosphate O-acyltransferase [KO:K00655] [EC:2.3.1.51]
SAVERM_6783  plsC4; putative 1-acylglycerol-3-phosphate O-acyltransferase [KO:K00655] [EC:2.3.1.51]
SAVERM_6523  plsC7; putative 1-acylglycerol-3-phosphate O-acyltransferase [KO:K00655] [EC:2.3.1.51]
SAVERM_6694  dgkA; putative diacylglycerol kinase [KO:K07029] [EC:2.7.1.107]
SAVERM_1715  plcA; putative non-hemolytic phospholipase C, secreted [KO:K01114] [EC:3.1.4.3]
SAVERM_6271  glpQ6; putative glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
SAVERM_4224  glpQ2; putative glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
SAVERM_6927  glpQ4; putative glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
SAVERM_6784  glpQ3; putative glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
SAVERM_1492  glpQ5; putative glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
SAVERM_4544  eutB; putative ethanolamine ammonia-lyase large subunit [KO:K03735] [EC:4.3.1.7]
SAVERM_4545  eutC; putative ethanolamine ammonia-lyase small subunit [KO:K03736] [EC:4.3.1.7]
SAVERM_2623  cdsA; putative phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
SAVERM_1917  pssA; putative phosphatidylserine synthase [KO:K17103] [EC:2.7.8.8]
SAVERM_1916  psd; putative phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]
SAVERM_6826  pgsA2; putative phosphatidylglycerophosphate synthase [KO:K00995] [EC:2.7.8.5]
SAVERM_2507  pgsA1; putative phosphatidylglycerophosphate synthase [KO:K00995] [EC:2.7.8.5]
SAVERM_6976  pgsA3; putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase [KO:K08744] [EC:2.7.8.41]
SAVERM_1659  gldA; putative glycerol 1-phosphate dehydrogenase [KO:K00096] [EC:1.1.1.261]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
sma00010  Glycolysis / Gluconeogenesis
sma00260  Glycine, serine and threonine metabolism
sma00561  Glycerolipid metabolism
sma00562  Inositol phosphate metabolism
sma00620  Pyruvate metabolism
KO pathway
ko00564   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG GENES (23)   
All databases (24)   

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