KEGG   PATHWAY: tbg00230
Entry
tbg00230                    Pathway                                
Name
Purine metabolism - Trypanosoma brucei gambiense
Class
Metabolism; Nucleotide metabolism
Pathway map
tbg00230  Purine metabolism
tbg00230

Module
tbg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:tbg00230]
tbg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tbg00230]
tbg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tbg00230]
tbg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tbg00230]
Other DBs
GO: 0006163 0042278
Organism
Trypanosoma brucei gambiense [GN:tbg]
Gene
TbgDal_V4160  phosphoribosylpyrophosphate synthetase, putative [KO:K00948] [EC:2.7.6.1]
TbgDal_V4420  ribose-phosphate pyrophosphokinase, putative [KO:K00948] [EC:2.7.6.1]
TbgDal_X11530  phosphoribosylpyrophosphate synthetase, putative [KO:K00948] [EC:2.7.6.1]
TbgDal_XI3350  phosphoribosylpyrophosphate synthetase, putative [KO:K00948] [EC:2.7.6.1]
TbgDal_IX4120  adenylosuccinate lyase, putative [KO:K01756] [EC:4.3.2.2]
TbgDal_VII1780  Adenine phosphoribosyltransferase, putative [KO:K00759] [EC:2.4.2.7]
TbgDal_VII1790  Adenine phosphoribosyltransferase, putative [KO:K00759] [EC:2.4.2.7]
TbgDal_III3040  IAG-nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
TbgDal_X1600  hypoxanthine-guanine phosphoribosyltransferase,putative [KO:K00760] [EC:2.4.2.8]
TbgDal_X1690  hypoxanthine-guanine phosphoribosyltransferase,putative [KO:K00760] [EC:2.4.2.8]
TbgDal_X19740  IMP dehydrogenase, putative [KO:K00088] [EC:1.1.1.205]
TbgDal_IV1630  nucleoside diphosphate kinase, putative [KO:K00940] [EC:2.7.4.6]
TbgDal_IX6720  nucleoside diphosphate kinase, putative [KO:K00940] [EC:2.7.4.6]
TbgDal_XI18090  nucleoside diphosphate kinase, putative [KO:K00940] [EC:2.7.4.6]
TbgDal_VII1920  nucleoside diphosphatase, putative [KO:K01511] [EC:3.6.1.6]
TbgDal_X12190  hypothetical protein, conserved [KO:K01519] [EC:3.6.1.66]
TbgDal_VII2290  GMP synthase, putative [KO:K01951] [EC:6.3.5.2]
TbgDal_V2930  inosine-5'-monophosphate dehydrogenase, putative [KO:K00364] [EC:1.7.1.7]
TbgDal_V6150  guanase, putative [KO:K01487] [EC:3.5.4.3]
TbgDal_X14110  guanylate kinase, putative [KO:K00942] [EC:2.7.4.8]
TbgDal_X8310  guanylate kinase, putative [KO:K00942] [EC:2.7.4.8]
TbgDal_XI8940  ribonucleoside-diphosphate reductase large chain [KO:K10807] [EC:1.17.4.1]
TbgDal_XI14270  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
TbgDal_XI14280  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
TbgDal_XI14290  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
TbgDal_IX6360  hypothetical protein, conserved [KO:K07023] [EC:3.1.3.89]
TbgDal_IX1630  acidocalcisomal exopolyphosphatase, putative [KO:K01514] [EC:3.6.1.11]
TbgDal_IV3790  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV3940  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_IV3960  receptor-type adenylate cyclase GRESAG, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV3970  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV3980  receptor-type adenylate cyclase GRESAG, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV3990  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV4510  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_IV4520  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV4530  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV4540  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV4550  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_IV4580  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_IX9790  expression site-associated gene 4 (ESAG4) protein, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_V1970  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_V20  receptor-type adenylate cyclase GRESAG, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_V210  adenylyl cyclase, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_V220  ATP pyrophosphate-lyase, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_V6140  ATP pyrophosphate-lyase, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_V890  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VI110  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VI490  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VI500  receptor-type adenylate cyclase GRESAG 4,putative, (fragment) [KO:K01768] [EC:4.6.1.1]
TbgDal_VI510  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VI520  receptor-type adenylate cyclase GRESAG 4,putative, (fragment) [KO:K01768] [EC:4.6.1.1]
TbgDal_VII7010  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_VII7020  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VII7030  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VII8760  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_VIII7870  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VIII8230  receptor-type adenylate cyclase, GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_VIII8240  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_VIII8250  receptor-type adenylate cyclase GRESAG 4,putative, (fragment) [KO:K01768] [EC:4.6.1.1]
TbgDal_VIII8700  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_X15760  ESAG 4 (expression site-associated gene 4) protein, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_X19590  expression site-associated gene 4 (ESAG4) protein, putative [KO:K01768] [EC:4.6.1.1]
TbgDal_X19830  expression site-associated gene (ESAG) protein,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_X19920  expression site-associated gene (ESAG) [KO:K01768] [EC:4.6.1.1]
TbgDal_X2990  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_XI10  expression site-associated gene (ESAG) [KO:K01768] [EC:4.6.1.1]
TbgDal_XI15330  receptor-type adenylate cyclase GRESAG 4,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_XI1570  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_XI1580  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_XI19250  expression site-associated gene (ESAG) protein,putative [KO:K01768] [EC:4.6.1.1]
TbgDal_XI6690  receptor-type adenylate cyclase GRESAG [KO:K01768] [EC:4.6.1.1]
TbgDal_X15680  3', 5'-cyclic nucleotide phosphodiesterase,putative [KO:K01120] [EC:3.1.4.17]
TbgDal_XI4160  adenylosuccinate synthetase, putative [KO:K01939] [EC:6.3.4.4]
TbgDal_IX3860  AMP deaminase, putative [KO:K01490] [EC:3.5.4.6]
TbgDal_IX5600  AMP deaminase, putative [KO:K01490] [EC:3.5.4.6]
TbgDal_XI17670  AMP deaminase, putative [KO:K01490] [EC:3.5.4.6]
TbgDal_VI2110  adenosine kinase, putative [KO:K00856] [EC:2.7.1.20]
TbgDal_VI2120  adenosine kinase, putative [KO:K00856] [EC:2.7.1.20]
TbgDal_II3970  adenylate kinase, putative [KO:K00939] [EC:2.7.4.3]
TbgDal_V5480  adenylate kinase, putative [KO:K00939] [EC:2.7.4.3]
TbgDal_X3150  adenylate kinase, putative [KO:K00939] [EC:2.7.4.3]
TbgDal_X3170  adenylate kinase, putative [KO:K00939] [EC:2.7.4.3]
TbgDal_X6990  adenylate kinase, putative [KO:K00939] [EC:2.7.4.3]
TbgDal_X880  adenylate kinase, putative [KO:K00939] [EC:2.7.4.3]
TbgDal_VI3000  hypothetical protein, conserved [KO:K18532] [EC:2.7.4.3]
TbgDal_III3220  3', 5'-cyclic nucleotide phosphodiesterase,putative [KO:K13293] [EC:3.1.4.53]
TbgDal_IX2700  cAMP-specific phosphodiesterase, putative [KO:K13294] [EC:3.1.4.53]
TbgDal_IX2710  cAMP-specific phosphodiesterase, putative [KO:K13294] [EC:3.1.4.53]
TbgDal_VIII2660  Bis(5'-adenosyl)-triphosphatase, putative [KO:K01522] [EC:3.6.1.29]
TbgDal_IV4420  serine/threonine protein phosphatase, putative [KO:K01525] [EC:3.6.1.41]
TbgDal_VIII8370  diadenosine tetraphosphatase, putative [KO:K01525] [EC:3.6.1.41]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tbg00030  Pentose phosphate pathway
tbg00220  Arginine biosynthesis
tbg00250  Alanine, aspartate and glutamate metabolism
tbg00260  Glycine, serine and threonine metabolism
tbg00340  Histidine metabolism
tbg00630  Glyoxylate and dicarboxylate metabolism
tbg00730  Thiamine metabolism
tbg00740  Riboflavin metabolism
tbg00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (91)   
   KEGG GENES (91)   
All databases (92)   

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