KEGG   Cutibacterium acnes TypeIA2 P.acn33: TIA2EST2_11380
Entry
TIA2EST2_11380    CDS       T01656                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
paz  Cutibacterium acnes TypeIA2 P.acn33
Pathway
paz00470  D-Amino acid metabolism
paz00550  Peptidoglycan biosynthesis
paz01100  Metabolic pathways
paz01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:paz00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    TIA2EST2_11380
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    TIA2EST2_11380
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    TIA2EST2_11380
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:paz01011]
    TIA2EST2_11380
Enzymes [BR:paz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     TIA2EST2_11380
Peptidoglycan biosynthesis and degradation proteins [BR:paz01011]
 Precursor biosynthesis
  Amino acid ligase
   TIA2EST2_11380
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp ATP-grasp_4 ATP-grasp_3 CPSase_L_D2 ATPgrasp_YheCD TTL GARS_A
Other DBs
NCBI-ProteinID: AEW80336
Position
2475327..2476310
AA seq 327 aa
MPSLSWHWLNGGMLQPVVVLAGGLSHQRDISLKSGRTVAQALRRVGHEVVEADIDSALIE
TLRANDGAVVFPMLHGGLGENGALLEVLQLMGIPYVGSSPATCRISFDKSIASRAVAAAG
IVTPQQVALPHDVFRELGAQTVMRSIAEKFGLPVIVKPARGGSSLGVTKVDGVDDLPQAV
ANAYAYDDMVVVEEFIVGTELAIGMITTSEGTRVLPAVEIRPVGGVYDYSAMYTGGETRL
TAPADISDTAAQTATAMARVVQKELDFSGISRVDAIVDESGRPVFLEAGAAPGMTATSLV
PVAMKAAGLDLGEVCSRLVDDVARNHG
NT seq 984 nt   +upstreamnt  +downstreamnt
atgccatcattgtcttggcactggttgaatgggggcatgttgcaaccagtcgtcgtcctt
gccggaggactcagccaccagcgcgatatctctctgaagtcgggtcgcaccgttgcacaa
gcgctgcggcgggtcggacacgaagtcgtggaagccgatattgactccgcactcattgag
accttgcgtgccaacgacggtgccgtcgtgtttcccatgttgcacggtggtcttggcgaa
aatggtgcccttcttgaagtacttcagctcatgggcatcccctatgtgggctccagtcca
gcaacctgccgtatctctttcgataagtccatcgcatctcgcgccgtggccgcagccggg
atcgtcacaccacagcaggtcgcgttaccccatgacgtcttccgtgagcttggcgctcag
acggtcatgcgttcgatcgccgaaaagtttggccttccggtcatcgttaagccggcacgt
gggggctcaagcctcggcgtcacaaaagtcgatggcgtcgacgatcttcctcaggccgtc
gcgaacgcctatgcctatgacgacatggttgtagtcgaggaattcattgtgggcactgag
ctcgcaataggcatgatcacgacgtctgaaggcacgcgtgtgctgccagccgtcgagatt
cgccctgtcggtggtgtttatgattattcagcgatgtacaccggtggtgagacacgacta
acagctcctgcagacattagcgatacagcggcccaaaccgcgacggcgatggcccgagtc
gtgcaaaaggagctcgatttctccgggatatctcgtgtcgatgcgatcgtggacgagtcc
ggtcgcccagttttcttggaggccggtgctgctcccgggatgacagctacttcgctcgta
cccgtggctatgaaagctgccggtctagaccttggcgaggtgtgctctcgactcgtcgat
gacgtcgctcgcaaccatggctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (9)   
   Pfam (9)   
All databases (27)   

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