KEGG   Physeter catodon (sperm whale): 102981822
Entry
102981822         CDS       T06011                                 
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
  KO
K08860  eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
Organism
pcad  Physeter catodon (sperm whale)
Pathway
pcad04137  Mitophagy - animal
pcad04140  Autophagy - animal
pcad04141  Protein processing in endoplasmic reticulum
pcad04210  Apoptosis
pcad04932  Non-alcoholic fatty liver disease
pcad05010  Alzheimer disease
pcad05012  Parkinson disease
pcad05014  Amyotrophic lateral sclerosis
pcad05020  Prion disease
pcad05022  Pathways of neurodegeneration - multiple diseases
pcad05160  Hepatitis C
pcad05162  Measles
pcad05168  Herpes simplex virus 1 infection
pcad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102981822 (EIF2AK3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102981822 (EIF2AK3)
   04137 Mitophagy - animal
    102981822 (EIF2AK3)
  09143 Cell growth and death
   04210 Apoptosis
    102981822 (EIF2AK3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    102981822 (EIF2AK3)
   05162 Measles
    102981822 (EIF2AK3)
   05168 Herpes simplex virus 1 infection
    102981822 (EIF2AK3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102981822 (EIF2AK3)
   05012 Parkinson disease
    102981822 (EIF2AK3)
   05014 Amyotrophic lateral sclerosis
    102981822 (EIF2AK3)
   05020 Prion disease
    102981822 (EIF2AK3)
   05022 Pathways of neurodegeneration - multiple diseases
    102981822 (EIF2AK3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102981822 (EIF2AK3)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102981822 (EIF2AK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcad01001]
    102981822 (EIF2AK3)
Enzymes [BR:pcad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102981822 (EIF2AK3)
Protein kinases [BR:pcad01001]
 Serine/threonine kinases: Other
  PEK family [OT]
   102981822 (EIF2AK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PQQ_2 Kdo Kinase-like ABC1
Other DBs
NCBI-GeneID: 102981822
NCBI-ProteinID: XP_023985565
Ensembl: ENSPCTG00005006626
UniProt: A0A2Y9T9Q8
Position
12:complement(11904137..11974424)
AA seq 1116 aa
MERAARPGSLARALLLLLLLPPLQLGLVTGTVAARRASDLPASTVEAAFGLGAAAAPTSA
VRVQAAGAVTAAEVTVEDAEALPAAAGEQEPREPEPDDEADLRPCRRSLVIISTLDGRIA
ALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPF
TVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDEMEQEEDIL
LLQRTQKTVRAVGPRSGSEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEQSKIIS
DVEEQEAAMMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLF
DDTSYTTNDGVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALES
VNSENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPY
DNGYYLPYYKRERNKRSTQITVRVLDNPNYSKNIRKKDPVLLLHWWKEIVGTILFCIVAT
TFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWSDIKNSGYVSRYLTDFEPI
QCLGRGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFN
AWLEAPPEKWQEKMDKIWLKDESTDWPLSSPSPADAPSVKMCRMDPFSTKERIEIIAPSP
RSRRSFSVGISCGQTGSSKSQFSPPEFSGMDHRDTSDAVCNLQDSCLTDCEGEDGTRDGS
DEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEPKTNRPPLGNHCADKLTAV
QHSSSKSSSEPTLSISPSRPTTLSLDLTKNSVEKLQPSSPKVYLYIQMQLCRKENLKDWL
NSRCTIEERERSVCLHIFLQIAEAVEFLHGKGLMHRDLKPSNIFFTVDDVVKVGDFGLVT
AMDQDEEDQLVLTPMPGYARHTGQVGTKLYMSPEQIHGNNYCHKVDIFSLGLILFELLYP
FGTHMERVRILTDVRDLKFPPLFTQKYPREYVMVQDMLSPSPTERPEAANIIENAIFEDL
EFPGKTVLRQRSRSLSSSGTKQSRHSSSSHSPLPSN
NT seq 3351 nt   +upstreamnt  +downstreamnt
atggagcgcgccgcccgcccggggtcgctggcacgagcgctgctgctgcttctgctgctg
ccgccgcttcaactggggctcgtgacggggacggtggccgcgcggcgcgcttccgacctc
cccgcatcgacagtggaggcggcgttcggcctgggggccgcggccgctccaacctcggcc
gtgcgggtgcaggcggcgggcgccgtgactgcggcggaggtgacggtggaggacgccgag
gcgctgccggcggccgcgggggagcaggagccgcgggagccggaaccggacgacgaggcc
gatcttcggccgtgccgcagatccttagtgattatcagcactttagatggccgaattgct
gccttggatcctgagaaccatggtaaaaagcagtgggatttggacgtgggatctggttcc
ttggtgtcatctagccttagcaaaccggaggtatttgggaataagatgatcattccttcc
ctggatggagacctcttccagtgggaccgggaccgtgagagcatggaaacagttccgttt
acagttgaatcacttcttgaatcttcttataaatttggagatgatgttgtcttggttgga
ggaaagtctctcactacatatggactcagtgcatatagcggaaaggtgaggtacatctgt
tcagctctgggttgtcgccagtgggataatgatgaaatggagcaagaagaagatatcctg
cttctgcagcgcacccagaaaaccgttagagccgtcggccctcgtagtggcagtgagaag
tggaatttcagtgttggccactttgaacttcggtatattccagacatggaaactagagct
ggatttattgaaagcaccttaaagcccagtggaaacaaagaacagtctaaaattatttca
gacgtggaagaacaggaagctgccatgatggacacagtgataaaggtctctgttgctgat
tggaaagttatggcctttagtaagaaaggaggacatctggagtgggaataccagttttgt
actcccattgcatctgcctggttggttaaggatggcaaagtcattcccatcagtcttttt
gatgatacaagttacaccactaatgatggagttttagaagatgaagaagacatcgtagaa
gccgcccgaggagccacagaaaacagtgtttacttgggaatgtacagaggccagctgtat
ctgcagtcatcagtcagaatttcagaaaagtttcctacgagtcccaaggccttggaatct
gtcaacagtgaaaatgcaattattcctttgccaacaatcaaatggaaacccttaattcat
tctccttccagaactcctgtcttggtggggtctgatgaatttgacaaatgtcttagtaat
gataagttttctcacgaagagtacagtaatggtgcactttcaatcttgcagtatccatat
gataatggttattacctgccatactacaagagggaaaggaacaaacggagcacacagatc
acagtcagagttctcgacaacccgaattacagcaagaatatccgcaaaaaggatcccgtt
ctcctcttacactggtggaaagaaatagttggaacgattctgttttgtatcgtagcaaca
actttcattgtgcgcagactcttccatcctcatcctcacagacaaaggaaagaatctgaa
actcagtgtcaaactgaaaataaatatgattctgtcagtggagaagctaatgacagtagc
tggagtgacataaaaaattctggatatgtatcacgctatctaacagattttgaaccgatt
cagtgcctgggtcgtggagggtttggagttgtctttgaagctagaaacaaagttgatgac
tgcaattatgctatcaagagaatccgtctccccaacagggaattggctcgggaaaaggta
atgcgagaagttaaagccttagccaagcttgaacacccaggaattgttagatatttcaat
gcttggttggaagcaccaccagagaagtggcaagaaaaaatggataaaatttggctgaaa
gatgaaagcacagactggccgctcagctctcctagtcccgcggatgcgccatccgttaaa
atgtgcagaatggatcctttctctacaaaggaacgcattgaaatcatagccccttctcca
cgaagcaggaggtctttttcggtcgggatttcctgtggccagacaggttcatccaagagc
cagttctctccgccggaattttccggaatggaccacagagacacgagtgacgcggtgtgc
aacctccaggacagctgccttacagactgcgagggggaagacgggactagggatggcagt
gatgagggacactcctttgaactttgtccttctgaagcttccccttacgtaaggtcaagg
gagcgaacctcctcttctatagtatttgaagattccggctgtgataacgcatccagcaaa
gagcccaaaacgaaccgaccgcctcttggcaaccattgtgctgataaactaactgcagtc
cagcattccagtagcaagtcttcctcggaacctactttgtctatttctccttcaagacca
accactttaagtttagatctcactaaaaactctgtggaaaaactccaacccagttcacca
aaggtgtatctttacatccagatgcagctgtgcagaaaggaaaacctcaaagactggctg
aatagccgctgcaccattgaggagagagagagaagcgtgtgtctgcacatcttcctgcag
atcgcagaggcggtggagtttctgcacggcaaagggctcatgcacagggacctcaagcct
tccaacatattctttacagtggatgatgtggtcaaggttggagactttggattggtgact
gcaatggaccaggatgaagaagaccagctggttctgaccccaatgccagggtacgccaga
cacacaggacaagtgggcaccaagctgtatatgagcccagaacagattcatggcaacaac
tactgtcataaagtggacatcttttctttaggcctcattctgtttgaattgctgtaccca
ttcggcactcacatggagagggtcaggatcttaactgatgtaagagatctcaaatttcca
ccactgtttactcagaaatatcctcgtgagtatgtaatggtgcaagacatgctctcccca
tcccctacggaacggcctgaagctgcaaacattattgaaaacgctatatttgaggacttg
gagtttccaggaaaaacagttctcagacagaggtctcgctccctgagctcatcgggaacg
aaacagtcaagacactccagcagctcccatagccctttgccaagcaattag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (14)   
   KEGG PATHWAY (14)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (34)   

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