KEGG   Physeter catodon (sperm whale): 102985820
Entry
102985820         CDS       T06011                                 

Gene name
ADCY4
Definition
(RefSeq) adenylate cyclase type 4 isoform X1
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
pcad  Physeter catodon (sperm whale)
Pathway
pcad00230  Purine metabolism
pcad01100  Metabolic pathways
pcad01522  Endocrine resistance
pcad04015  Rap1 signaling pathway
pcad04020  Calcium signaling pathway
pcad04022  cGMP-PKG signaling pathway
pcad04024  cAMP signaling pathway
pcad04062  Chemokine signaling pathway
pcad04072  Phospholipase D signaling pathway
pcad04114  Oocyte meiosis
pcad04211  Longevity regulating pathway
pcad04213  Longevity regulating pathway - multiple species
pcad04261  Adrenergic signaling in cardiomyocytes
pcad04270  Vascular smooth muscle contraction
pcad04371  Apelin signaling pathway
pcad04540  Gap junction
pcad04611  Platelet activation
pcad04713  Circadian entrainment
pcad04714  Thermogenesis
pcad04723  Retrograde endocannabinoid signaling
pcad04724  Glutamatergic synapse
pcad04725  Cholinergic synapse
pcad04727  GABAergic synapse
pcad04742  Taste transduction
pcad04750  Inflammatory mediator regulation of TRP channels
pcad04911  Insulin secretion
pcad04912  GnRH signaling pathway
pcad04913  Ovarian steroidogenesis
pcad04914  Progesterone-mediated oocyte maturation
pcad04915  Estrogen signaling pathway
pcad04916  Melanogenesis
pcad04918  Thyroid hormone synthesis
pcad04921  Oxytocin signaling pathway
pcad04923  Regulation of lipolysis in adipocytes
pcad04925  Aldosterone synthesis and secretion
pcad04926  Relaxin signaling pathway
pcad04927  Cortisol synthesis and secretion
pcad04928  Parathyroid hormone synthesis, secretion and action
pcad04934  Cushing syndrome
pcad04935  Growth hormone synthesis, secretion and action
pcad04970  Salivary secretion
pcad04971  Gastric acid secretion
pcad04972  Pancreatic secretion
pcad04976  Bile secretion
pcad05032  Morphine addiction
pcad05163  Human cytomegalovirus infection
pcad05166  Human T-cell leukemia virus 1 infection
pcad05200  Pathways in cancer
pcad05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102985820 (ADCY4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102985820 (ADCY4)
   04371 Apelin signaling pathway
    102985820 (ADCY4)
   04020 Calcium signaling pathway
    102985820 (ADCY4)
   04072 Phospholipase D signaling pathway
    102985820 (ADCY4)
   04024 cAMP signaling pathway
    102985820 (ADCY4)
   04022 cGMP-PKG signaling pathway
    102985820 (ADCY4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102985820 (ADCY4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102985820 (ADCY4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102985820 (ADCY4)
   04062 Chemokine signaling pathway
    102985820 (ADCY4)
  09152 Endocrine system
   04911 Insulin secretion
    102985820 (ADCY4)
   04923 Regulation of lipolysis in adipocytes
    102985820 (ADCY4)
   04912 GnRH signaling pathway
    102985820 (ADCY4)
   04913 Ovarian steroidogenesis
    102985820 (ADCY4)
   04915 Estrogen signaling pathway
    102985820 (ADCY4)
   04914 Progesterone-mediated oocyte maturation
    102985820 (ADCY4)
   04921 Oxytocin signaling pathway
    102985820 (ADCY4)
   04926 Relaxin signaling pathway
    102985820 (ADCY4)
   04935 Growth hormone synthesis, secretion and action
    102985820 (ADCY4)
   04918 Thyroid hormone synthesis
    102985820 (ADCY4)
   04928 Parathyroid hormone synthesis, secretion and action
    102985820 (ADCY4)
   04916 Melanogenesis
    102985820 (ADCY4)
   04925 Aldosterone synthesis and secretion
    102985820 (ADCY4)
   04927 Cortisol synthesis and secretion
    102985820 (ADCY4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102985820 (ADCY4)
   04270 Vascular smooth muscle contraction
    102985820 (ADCY4)
  09154 Digestive system
   04970 Salivary secretion
    102985820 (ADCY4)
   04971 Gastric acid secretion
    102985820 (ADCY4)
   04972 Pancreatic secretion
    102985820 (ADCY4)
   04976 Bile secretion
    102985820 (ADCY4)
  09156 Nervous system
   04724 Glutamatergic synapse
    102985820 (ADCY4)
   04727 GABAergic synapse
    102985820 (ADCY4)
   04725 Cholinergic synapse
    102985820 (ADCY4)
   04723 Retrograde endocannabinoid signaling
    102985820 (ADCY4)
  09157 Sensory system
   04742 Taste transduction
    102985820 (ADCY4)
   04750 Inflammatory mediator regulation of TRP channels
    102985820 (ADCY4)
  09149 Aging
   04211 Longevity regulating pathway
    102985820 (ADCY4)
   04213 Longevity regulating pathway - multiple species
    102985820 (ADCY4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102985820 (ADCY4)
   04714 Thermogenesis
    102985820 (ADCY4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102985820 (ADCY4)
  09165 Substance dependence
   05032 Morphine addiction
    102985820 (ADCY4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    102985820 (ADCY4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102985820 (ADCY4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102985820 (ADCY4)
   05163 Human cytomegalovirus infection
    102985820 (ADCY4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102985820 (ADCY4)
Enzymes [BR:pcad01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     102985820 (ADCY4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N CD52
Other DBs
NCBI-GeneID: 102985820
NCBI-ProteinID: XP_007130093
UniProt: A0A2Y9FV52
Position
Unknown
AA seq 1077 aa
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLFGLLALLAVAWASGRELASDPG
FLTSMLCGLGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV
SFFLFVIFTVYAMLPLGMRDAAAAGLASSLSHLLVLGLYLGPQPDSQPALLPQLAANAVL
FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKDLVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAG
AYAVEDAAMEHGDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR
YLESWGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQWSLDRSRTPRGLDDELDTGDAK
FFQVIEQLNSQKQWKQSEDFNPLTLYFREKEMEKEYRLSALPAFKYYVACTFLVFFSNFI
IQMLVTNRPPALTITYSITFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPTLSVLVATRP
GLRVALGTATILLVFSMAITSLVFFPAASSCPFRAPNVSSTASNLSWELPGSLPLISVPY
SVHCCALGSLSCSLFLHLSFELKLLLLVLWLAASCSLFLRSHAWLSDCLIARLYLGASDS
RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRL
LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESSINHEGLECLR
LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAEQSCSHLGTMV
EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST
GVLGKIQVTEETACALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG
NT seq 3234 nt   +upstreamnt  +downstreamnt
atggcccgcctcttcagtccccggccgcctcccagcgaagacctcttctacgagacctac
tacagcctgagccagcagtacccactgctgctactgctgctggtgatagtgctcttcggg
ctcttggcgctgctcgctgttgcctgggccagcggcagggagctggcctcagacccgggc
ttcctgacctctatgctgtgcgggctgggcggcttctcgctgctgctgggcctggcttcc
cgcgagcagcgactgcagcgctggacgcgtcccctgtcgggcctcgtgtgggcagcgctg
ctcgcgctaggccacggcttcctcttcaccgggggcgtggtgagcgcctgggaccaggtg
tcctttttcctttttgtcatcttcaccgtgtatgccatgttgcccttgggcatgcgggac
gccgccgccgcgggtctcgcctcttcactctcacacctgctggtcctcgggctgtatctt
gggcctcagccggactcacagcccgcgctgctgccgcagctggcagcaaacgcggtgttg
ttcctgtgcgggaacgtggccggagcataccacaaggcgctgatggagcgcgcgctgcgc
gccacgttccgggaggcgcttagttccctgcactcccgccggagactcgacaccgagaag
aagcaccaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaag
gcggagatcatggcacggctgcaggctggacaggggtcacggccggagagcaccaacaac
ttccacagcctctatgtcaagaggcaccagggagtgagcgtgctgtatgctgacatcgtg
ggcttcacgcggctggccagtgagtgctctcctaaggacttggtgcttatgcttaacgag
ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg
ggagactgttactactgtgtctccgggctgccgctctcgctgccagaccacgccatcaac
tgcgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccaccggc
gtggatatcaacatgcgcgtgggtgtgcactcgggcagcgtgctctgcggggtcatcggg
ctgcagaaatggcagtatgatgtctggtcgcatgacgtcactctggccaaccacatggag
gcgagtggagtgccaggacgagtacatatcacaggggctacgttggcactgctggcaggg
gcttatgctgtggaggatgcagccatggaacacggggacccataccttcgggagctaggg
gagccgacctaccttgtcatcgatccccgggctgaggaagaggacgagaagggcactgca
ggcgggttgctgtcctctcttgagggccccaagatgcgtccgtcactgctgatgacccgc
tacctggagtcctggggtgcagccaagcctttcgcccacctgagccatgtggagagccct
gtgtccacctccacccctctcccagagaaggccctgtcttccttcagcccccagtggagc
ctggaccggagccgtaccccccgggggctagatgatgaactggacaccggggatgccaag
ttcttccaagtcatcgaacagctcaactctcagaaacagtggaaacagtcagaggacttc
aacccattgacactgtacttcagagagaaggagatggagaaagagtatcggctctctgca
ctccccgccttcaaatactatgtagcctgcaccttcctggtttttttctccaacttcatc
atccagatgctggtgacaaacaggcccccagctctgaccatcacctatagcatcaccttc
ctcctcttcttcctcctcctcttcgtctgcttctcagagcacctgacgaaatgtgtcttg
aaaggccccaagatgctgcactggctgcccacactgtctgtcctagtggccacgcggccc
ggactgcgagttgccctgggcaccgctaccatcctgctcgtcttctccatggccattacc
agcctggtcttcttcccggcagcatccagctgccctttccgggctcccaatgtgtcctcc
acggcttccaacctctcctgggagctccctgggtccctgcctctcatcagcgtcccatac
tccgtgcactgctgcgcgctgggctccctctcctgctccctcttcctgcacctgagcttc
gagctgaagctgctgctgctcgtgctgtggctggcggcctcctgctccctcttcctgcgc
tcccacgcctggctgtccgactgtctcatcgcccgcctctatctgggcgcctcggactcc
aggccaggggtgctgaaggagcctaaactgatgggagcaatctccttcttcatcttcttc
ttcaccctcctggtcctggctcggcagaatgagtattactgccgcctggacttcctgtgg
aagaagaagctgaggcaggagcaggaggagacagagacgatggaaaacctgactcggctg
ctcttggagaatgtgctccccgcgcacgtagccccccagttcatcggccagaatcggcgc
aatgaggacctctaccaccagtcctacgagtgtgtttgtgtcctcttcgcctcagtccca
gactttaaggagttttactctgaatccagcatcaaccatgaggggctagagtgtctgcgg
ctgctcaatgagataattgctgattttgatgagctgctctccaagcccaagttcagtggg
gtggagaaaatcaaaactatctgcagcacctacatggcagctacaggcttgaacgccacc
tctggacaggacgctcagcaggatgctgagcaaagctgcagccaccttggcaccatggta
gagtttgccgtggcccttgggtctaagctggacgtcatcaacaagcactcattcaacaac
ttccgcttgcgtgtggggttaaaccacggacctgtagtggccggagtgattggggcccag
aaaccacaatatgacatctggggcaacacggtgaacgtggccagccgaatggagagtaca
ggcgtcctgggcaagatccaagtgaccgaagagacagcctgcgccctgcagtccttaggc
tacacctgctacagccggggcatcatcaaggtcaaaggcaaagggcagctctgcacctac
ttcctgaacacagatttgacacgaactggacctccctcagccaccctaggctga

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