KEGG   Phascolarctos cinereus (koala): 110211020
Entry
110211020         CDS       T05867                                 
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw04014  Ras signaling pathway
pcw04137  Mitophagy - animal
pcw04140  Autophagy - animal
pcw04620  Toll-like receptor signaling pathway
pcw04621  NOD-like receptor signaling pathway
pcw04622  RIG-I-like receptor signaling pathway
pcw04623  Cytosolic DNA-sensing pathway
pcw04657  IL-17 signaling pathway
pcw04936  Alcoholic liver disease
pcw05014  Amyotrophic lateral sclerosis
pcw05022  Pathways of neurodegeneration - multiple diseases
pcw05135  Yersinia infection
pcw05160  Hepatitis C
pcw05161  Hepatitis B
pcw05162  Measles
pcw05163  Human cytomegalovirus infection
pcw05164  Influenza A
pcw05165  Human papillomavirus infection
pcw05167  Kaposi sarcoma-associated herpesvirus infection
pcw05168  Herpes simplex virus 1 infection
pcw05169  Epstein-Barr virus infection
pcw05170  Human immunodeficiency virus 1 infection
pcw05171  Coronavirus disease - COVID-19
pcw05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    110211020 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110211020 (TBK1)
   04137 Mitophagy - animal
    110211020 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110211020 (TBK1)
   04621 NOD-like receptor signaling pathway
    110211020 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    110211020 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    110211020 (TBK1)
   04657 IL-17 signaling pathway
    110211020 (TBK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110211020 (TBK1)
   05161 Hepatitis B
    110211020 (TBK1)
   05160 Hepatitis C
    110211020 (TBK1)
   05171 Coronavirus disease - COVID-19
    110211020 (TBK1)
   05164 Influenza A
    110211020 (TBK1)
   05162 Measles
    110211020 (TBK1)
   05168 Herpes simplex virus 1 infection
    110211020 (TBK1)
   05163 Human cytomegalovirus infection
    110211020 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110211020 (TBK1)
   05169 Epstein-Barr virus infection
    110211020 (TBK1)
   05165 Human papillomavirus infection
    110211020 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    110211020 (TBK1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110211020 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    110211020 (TBK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110211020 (TBK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110211020 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcw01001]
    110211020 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pcw04131]
    110211020 (TBK1)
Enzymes [BR:pcw01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     110211020 (TBK1)
Protein kinases [BR:pcw01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   110211020 (TBK1)
Membrane trafficking [BR:pcw04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    110211020 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like ABC1 DUF713 CEP63 COG6_N ECM11 Casc1_N
Other DBs
NCBI-GeneID: 110211020
NCBI-ProteinID: XP_020845846
UniProt: A0A6P5KN42
Position
Unknown
AA seq 729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAVKVFNSISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLVMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARVLEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSADMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIVHVFSLQQMTAHKIYIHSCNTATVFHDLVYKQTKIVSSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIIVVSREPMSTVGLMYEKVSLPKIHPRYDLDNDAGVAKVITG
VVCYACRVASTLLLYQELMRKGIRWLIELIKEDYNETIHKKTEVVIALDFCISNIEKTVK
IYEKLMQIDLEAAELGEISDIHTKLLRLSSSQGTIETSLQDTKSRLSPGGLLADAWANQE
GTHPEDRNVEKLQVLLNCITEIYCQFKKDKAERRLAYNEEQIHKFDKQKLCFYATKAMSH
FADECVEKYETFLDKAEEWMRKMLHLRKQLSSLTNQCFDMEEEVSKYQDYINELQETLPQ
KLFAASSAVKHSMAPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGALTMD
GGLRNVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagtacttctaatcatctgtggctcctatctgatatcctagggcaaggagccact
gcaaatgtctttcgtggaagacataagaaaactggtgatttatttgcggtcaaggtattt
aatagcataagtttccttcgtcctgtggatgttcagatgagagaatttgaagtcttaaaa
aaattaaaccacaagaatattgtcaaattgtttgctattgaagaggagacaaccacaaga
cataaagtactcgttatggaattttgcccatgtggtagtttatatactgtcttagaagaa
ccatctaatgcctatggactaccagaatcggagtttttaattgtgttgagagatgtggtg
ggtggaatgaatcacctccgagaaaatggaatagtgcaccgtgacatcaagccgggcaat
atcatgcgtgttataggggaagatggacagtctgtttacaaactgacagattttggtgct
gctagagtattagaagatgatgagcaatttgtttctttgtatggcacagaagaatatttg
catcctgatatgtatgaacgagcagtgctaaggaaagatcatcagaagaaatatggtgca
acagttgatctttggagcattggagtaacattttaccatgctgcaacagggtcactaccc
ttccgcccttttgaaggacctagacgaaacaaagaagtaatgtataaaataattactgga
aaaccttctggtgcaatatcaggagtacaaaaagcagaaaatgggccaattgactggagt
gcagacatgcctgtttcttgtagcctttctaggggtctgcaagtactactaacccctgtt
cttgcaaacattcttgaagctgaccaggaaaaatgctggggttttgaccagttttttgct
gaaactagcgatatacttcaccgaatgatagtgcatgttttttctttacaacaaatgaca
gcccacaagatttatattcatagttgtaatactgctactgtattccatgatttggtttat
aaacagaccaaaattgtttcttcaaatcaagaattgatctatgaaggacgacgattagtg
cttgaacctggaagactggcacagcatttccctaaaactactgaagaaaatcccatcatt
gtagtaagccgggaacctatgagcactgtaggattaatgtatgaaaaagtttcactacct
aaaatacatccacgttatgatttggataatgatgctggtgtggctaaggtaataacaggt
gtcgtctgttatgcctgtagagttgccagtaccttgctcctttatcaggaattgatgcga
aaaggaatacgatggttgattgaactgattaaagaagattataatgaaaccatacacaaa
aagacagaagttgtgattgctctggatttctgtatcagcaacattgaaaaaactgtgaaa
atatatgaaaaactgatgcagattgatttggaagcagctgagctgggtgaaatttcagac
atacacactaaattgttgcgactctccagttcacagggaacaatagaaaccagtcttcag
gataccaagagcagactgtctcctgggggcctgttggcagatgcctgggcaaaccaagaa
gggacacacccagaagaccgaaatgtagaaaaactgcaagtcctgctgaattgcattaca
gagatttactgtcagttcaaaaaagacaaagcggaacgtagactagcttacaatgaagaa
cagattcacaaatttgacaagcagaaactgtgcttttatgcaacaaaagctatgagccac
tttgctgatgagtgtgttgaaaaatatgaaacatttttggataaggcagaagagtggatg
agaaagatgcttcacctaaggaaacagttgtcatctctaactaatcagtgttttgatatg
gaggaagaggtatcaaagtaccaggactatattaatgagttacaggaaactttacctcag
aaattgtttgcagcttccagtgcagtaaaacatagcatggctcccatttatccaagctcc
aacacactggtggagatgactcttggcatgaagaaattgaaggaagagatggaaggtgtt
gttaaagaacttgctgaaaataatcatattttagagagatttggcgctttgactatggat
ggtggccttcggaatgttgattgcctctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (24)   
   KEGG PATHWAY (24)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (12)   
   Pfam (12)   
All databases (48)   

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