KEGG   Phascolarctos cinereus (koala): 110220704
Entry
110220704         CDS       T05867                                 
Symbol
ACTN1
Name
(RefSeq) alpha-actinin-1 isoform X1
  KO
K05699  actinin alpha 1/4
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw04510  Focal adhesion
pcw04520  Adherens junction
pcw04530  Tight junction
pcw04670  Leukocyte transendothelial migration
pcw04810  Regulation of actin cytoskeleton
pcw05146  Amoebiasis
pcw05203  Viral carcinogenesis
pcw05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110220704 (ACTN1)
   04520 Adherens junction
    110220704 (ACTN1)
   04530 Tight junction
    110220704 (ACTN1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110220704 (ACTN1)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    110220704 (ACTN1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    110220704 (ACTN1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110220704 (ACTN1)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    110220704 (ACTN1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pcw04131]
    110220704 (ACTN1)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:pcw04812]
    110220704 (ACTN1)
   04147 Exosome [BR:pcw04147]
    110220704 (ACTN1)
Membrane trafficking [BR:pcw04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    110220704 (ACTN1)
Cytoskeleton proteins [BR:pcw04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     110220704 (ACTN1)
Exosome [BR:pcw04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   110220704 (ACTN1)
  Exosomal proteins of colorectal cancer cells
   110220704 (ACTN1)
  Exosomal proteins of bladder cancer cells
   110220704 (ACTN1)
SSDB
Motif
Pfam: Spectrin CH EFhand_Ca_insen EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_7 EF-hand_5 XisI Uds1 U3_assoc_6
Other DBs
NCBI-GeneID: 110220704
NCBI-ProteinID: XP_020860502
UniProt: A0A6P5LQ35
Position
Unknown
AA seq 914 aa
MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFR
DGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNV
KMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFC
ALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMT
YVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTVPWLENR
TPENTMQAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKM
VSDINNAWGGLEQAEKGYEEWQLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLQQK
DYEIATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYNSPSVNARCQKIC
DQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHT
IEEIQGLTTAHEQFKATLPDADKERQAILGIHNEVTKIVQTYHVNMAGTNPYTTITPQEI
NGKWDHVRQLVPRRDQALMEEHTRQQQNERLRKQFAAQANVIGPWIQTKMEEIGRISIEM
HGTLEDQLNHLRQYEKSIVNYKPKIDQLEGDHQQIQEALIFDNKHTNYTMEHIRVGWEQL
LTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGY
DIGNDPQKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRIGVVTFQAFIDFMSR
ETADTDTADQVMASFKILAGDKNYITLDELRRELPPDQAEYCIARMAPYTGPDAVPGALD
YMSFSTALYGESDL
NT seq 2745 nt   +upstreamnt  +downstreamnt
atggatcattatgattcccaacagaccaacgactacatgcagccggaagaggactgggac
agagacttgctccttgaccccgcctgggagaagcagcaaagaaagacattcacagcgtgg
tgcaattcacacctccgaaaggcgggcacacagattgagaacatagaggaggatttccgg
gatggcctgaagctcatgttgctactggaggtcatttcaggtgaacgtttggccaagcca
gagcgaggcaagatgagggtgcacaaaatctccaacgtgaataaggccctggacttcatt
gctagcaaaggggtcaaactggtgtccattggagcagaagaaattgtggatgggaatgtg
aaaatgaccctagggatgatttggaccatcatccttcgctttgctattcaggatatctca
gtggaagagacatcagcaaaggaagggctgctgctatggtgtcagaggaagacggctcca
tataaaaatgtaaacattcagaacttccacatcagctggaaagatggccttgggttctgc
gcactgattcacagacaccggccagaactcatcgattacgggaagctgcggaaggatgat
ccactcacaaacctaaatacagcttttgatgtggcagagaagtatctggatatcccaaag
atgctggatgcagaagacattgttggaactgcccgccctgatgaaaaggccatcatgacc
tatgtttctagtttctaccacgccttctcaggagcccaaaaggcggagacagcagctaat
cggatctgcaaggtgctggcagtcaaccaggagaatgagcagctgatggaggactatgag
aagttggccagtgatctgctggagtggatccgtcgcactgtcccgtggttggagaaccgg
acccctgagaacaccatgcaggccatgcagcagaaactggaggacttccgagactaccgc
cgcctgcacaagccccctaaggtccaggaaaagtgccagttggagatcaactttaacaca
ttgcaaaccaaactccgactcagtaacaggcctgccttcatgccctctgaggggaagatg
gtctcggatatcaataatgcgtgggggggcctggagcaggcagagaagggctatgaggag
tggcagttgaacgagatccggaggttagagcgactggaccacctggctgagaagttccgg
cagaaggcctctatccatgaagcctggacagatggcaaggaggccatgttgcagcagaag
gactatgagatagccaccctttccgagatcaaggccttgctgaagaagcatgaggccttt
gagagtgacctcgctgctcaccaggaccgagtggaacagattgctgctatcgcacaggag
ctgaatgaattggattactacaattctcccagtgtcaatgctcgttgccaaaagatctgt
gaccagtgggacaacttgggagcgttgacccaaaagagaagggaagctttggagcggaca
gagaaactgctagagacaatagaccaactgtatctggaatatgccaagagagctgctccc
tttaataactggatggaaggggccatggaagacctgcaagatacattcattgtgcatacc
atagaggagatccagggattgaccacagcccatgaacaattcaaagctaccctccctgat
gctgacaaggagcgacaggccattctaggaatccataatgaagttaccaaaatcgtccag
acataccatgtcaatatggctgggaccaatccctacacaaccatcacccctcaggagatc
aatggcaaatgggatcatgttcggcaactagtaccacggagggaccaggccctgatggag
gagcacacccgtcagcagcagaatgaacgactccgcaaacagtttgcagcccaggccaat
gttattgggccctggatccagaccaagatggaggagattggccgcatctccatcgagatg
catggcaccttggaggaccagctcaatcaccttcgacagtatgagaagagcattgttaat
tacaaaccaaagattgaccagctggaaggagaccaccagcagatccaggaggctcttatt
tttgacaacaagcataccaactataccatggagcacatccgagtgggctgggaacagctc
ctcaccaccattgccagaaccatcaatgaagtggagaaccagatccttactcgagatgcc
aaagggatcagccaggagcagatgaatgagttccgagcctccttcaaccactttgaccgg
gatcactccggcacactcggtcctgaggagttcaaagcctgcctcatcagcttgggttac
gatattggcaacgacccccagaagaagacaggcatgatggacacagacgatttccgcgcc
tgccttatctccatgggttacaatatgggagaagcagagttcgcccgaatcatgagcatt
gtagaccctaaccgcattggcgtagtgacattccaggccttcatcgatttcatgtcccgt
gagacagccgatacagacacagctgaccaagtcatggcttccttcaagatcctggctggg
gacaagaattatatcaccttggatgaactacgccgggaactcccacctgaccaagcagaa
tactgcattgcacggatggccccctacacaggcccagatgcagtgcctggtgctctggac
tacatgtccttctccacagccctctatggcgaaagtgacctttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (11)   
   Pfam (11)   
All databases (34)   

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