KEGG   Phascolarctos cinereus (koala): 110222669
Entry
110222669         CDS       T05867                                 
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw00140  Steroid hormone biosynthesis
pcw00980  Metabolism of xenobiotics by cytochrome P450
pcw01100  Metabolic pathways
pcw05204  Chemical carcinogenesis - DNA adducts
Module
pcw_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    110222669 (HSD11B1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    110222669 (HSD11B1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    110222669 (HSD11B1)
Enzymes [BR:pcw01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     110222669 (HSD11B1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR DUF1776 Shikimate_DH THF_DHG_CYH_C
Other DBs
NCBI-GeneID: 110222669
NCBI-ProteinID: XP_020863429
UniProt: A0A6P5M4H9
Position
Unknown
AA seq 295 aa
MALLKKCFLSALGLLLAYYFYPATDSFRPEMLQGKRVIVTGASTGIGEQIAYHLARMGAH
LVVTARTEAKLKKVISECLKLGAASAHFIPGTMEDLVFAEQVVTKAGKLMGGLDMLILNH
IAPVNLRFFNGDVASIRKVMDINFFSYITMTSAALPMLKVTNGSIVVVSSIAGKLITPLI
ADYSAAKFALDGFYSSLQKELQLMNVNISITLCILGFINTDSAVKSLSGIVENITPSPKE
ECAVEIIKGGALRQKVIAYPSSIYISMWNPIRTIQEYFILLTYNIDNITRNQQFS
NT seq 888 nt   +upstreamnt  +downstreamnt
atggctctactgaaaaagtgcttcctctctgcgttgggactcttgttggcgtactatttc
tacccagccactgatagcttcagacctgagatgctccaagggaaaagggtaattgtcact
ggtgccagcacaggcattggagaacaaatagcctatcacctagcacggatgggagcccac
ttggtggtgacagcacggactgaggcaaagctgaagaaagtcatctctgaatgtttgaaa
ctaggagcagcctcagcacacttcatccctggaaccatggaggacttagtttttgcagag
caagtagtcactaaggcaggaaagctgatggggggattggacatgctcatcctcaaccat
atagcacctgtaaatttgaggttttttaatggtgatgttgccagcattcgcaaagtaatg
gatatcaacttctttagttatataaccatgacatcagctgccctacccatgctgaaagtc
accaatggaagcatcgtggtggtctcctcaatagcagggaaactaattacaccacttatt
gctgactactcggcagccaagtttgctctagatggattctattcttcactgcaaaaagaa
ttacaactaatgaacgtcaacatatccatcacactctgcatccttggcttcataaacaca
gattcagctgtaaaatctctttctgggattgtggaaaatataactccatctccaaaggag
gaatgtgcagtagagatcattaaagggggagctttgcgtcagaaagtaatagcttaccca
tcctctatctatatctcaatgtggaatccaattcgaacaatacaggaatattttatatta
ttaacatacaacatagataacattacaagaaatcaacagttctcttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (6)   
   Pfam (6)   
All databases (45)   

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