KEGG   Phascolarctos cinereus (koala): 110223736Help
Entry
110223736         CDS       T05867                                 

Gene name
PLA2G4E
Definition
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw00564  Glycerophospholipid metabolism
pcw00565  Ether lipid metabolism
pcw00590  Arachidonic acid metabolism
pcw00591  Linoleic acid metabolism
pcw00592  alpha-Linolenic acid metabolism
pcw01100  Metabolic pathways
pcw04010  MAPK signaling pathway
pcw04014  Ras signaling pathway
pcw04072  Phospholipase D signaling pathway
pcw04217  Necroptosis
pcw04270  Vascular smooth muscle contraction
pcw04370  VEGF signaling pathway
pcw04611  Platelet activation
pcw04664  Fc epsilon RI signaling pathway
pcw04666  Fc gamma R-mediated phagocytosis
pcw04724  Glutamatergic synapse
pcw04726  Serotonergic synapse
pcw04730  Long-term depression
pcw04750  Inflammatory mediator regulation of TRP channels
pcw04912  GnRH signaling pathway
pcw04913  Ovarian steroidogenesis
pcw04921  Oxytocin signaling pathway
pcw05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    110223736 (PLA2G4E)
   00565 Ether lipid metabolism
    110223736 (PLA2G4E)
   00590 Arachidonic acid metabolism
    110223736 (PLA2G4E)
   00591 Linoleic acid metabolism
    110223736 (PLA2G4E)
   00592 alpha-Linolenic acid metabolism
    110223736 (PLA2G4E)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    110223736 (PLA2G4E)
   04010 MAPK signaling pathway
    110223736 (PLA2G4E)
   04370 VEGF signaling pathway
    110223736 (PLA2G4E)
   04072 Phospholipase D signaling pathway
    110223736 (PLA2G4E)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    110223736 (PLA2G4E)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110223736 (PLA2G4E)
   04664 Fc epsilon RI signaling pathway
    110223736 (PLA2G4E)
   04666 Fc gamma R-mediated phagocytosis
    110223736 (PLA2G4E)
  09152 Endocrine system
   04912 GnRH signaling pathway
    110223736 (PLA2G4E)
   04913 Ovarian steroidogenesis
    110223736 (PLA2G4E)
   04921 Oxytocin signaling pathway
    110223736 (PLA2G4E)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    110223736 (PLA2G4E)
  09156 Nervous system
   04724 Glutamatergic synapse
    110223736 (PLA2G4E)
   04726 Serotonergic synapse
    110223736 (PLA2G4E)
   04730 Long-term depression
    110223736 (PLA2G4E)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110223736 (PLA2G4E)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    110223736 (PLA2G4E)
Enzymes [BR:pcw01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     110223736 (PLA2G4E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B cPLA2_C2 C2
Motif
Other DBs
NCBI-GeneID: 110223736
NCBI-ProteinID: XP_020865070
Position
Unknown
AA seq 868 aa AA seqDB search
MSQQVPGGSPDLGNNMSAPPNLQGAEEDSWMGRELSNSEDVQDLGPPVCPPSLPTIPQDS
QDQFPCHLLSVRIIRMKNVRQADVLSLTDCFVSLWLPTASHEKQRTRTISNCRNPEWNET
FNFRIQSQVKNVLELSVCDEDSLTPDDHLLTVLYDLSKLCFRKRTHVKFPLNPEGMEELE
VEFLLEESPAPPESLLTNGVLVSRQVSCLEVHVKHKKQKKNRKRKQLSVTVNESYENTQY
ISPCYSSSNQCPDLAFFHYTKYFQPQMHVEVPRSRWTCGLSCCCGTHKGNRSVCMSLDCL
PDGQELTVPMNENCDLHVTAKDCPDELNVRLGYSLCSEELEFLQKRKVIVAEALKQVLQL
EQNLQDNEVPLVAIMATGGGLRSMTSMYGHLLGLQKLNILNCTSYITGLSGASWTMSNLY
KDADWSSKNLEKAIQEARRHAVKNKIPSLCPEQLGYYQQNLKQRSQEGYRVTFTDLWGLL
IESFLGDEKYEGKLSWQKEALCQGQNPLPIYLTINVKDDVSNQDFREWVEFTPYEVGFQK
YGAYVPTEYFGSEFYMGRLMKRIPESRLCYLLGLWSSIFSLNMLDAWNLSHSSEEFFHRW
TREKVHDIEDEPLLPEIPKCDTNVLETTVVLPATKLANTLRDVLTYRAFVSQFHNFLQGL
QLHTDYLQNSQFTTWKDTVLDCFPNRLTQAESHLCLLDTAFFINSSYPPLLRPERKADII
IHLNYCAGSQIKPLKQTCEYCKVQNIPFPKYSVKEEGEEHLKECYLLTPDEDDPDAPIVL
FFPLINGSFQKYKAPGVERSPEEMEDGHVDIYSHNTPYATKEVTYTESAFDRMVNLSEYN
ILNNADTILQGLRLAVERKKQFKKACSS
NT seq 2607 nt NT seq  +upstreamnt  +downstreamnt
atgagccagcaggttccaggaggcagtccagaccttggaaacaatatgtctgcccccccg
aatctccagggggctgaagaggacagttggatgggaagggagttgagcaactctgaggat
gtacaggatctggggccacctgtctgcccaccttcgcttcctaccatcccccaggattct
caggaccagtttccctgtcatcttctctcagtgaggatcattcggatgaaaaatgtccgt
caggctgatgtgttgagtctgacagactgcttcgtaagtctctggctcccaaccgcctcc
cacgagaagcagagaacaaggactatctccaactgtcgcaacccggagtggaatgaaacc
ttcaacttccggatccagagccaggtgaagaatgtgcttgaactaagtgtctgtgatgag
gactcacttactccagatgatcacctcttgactgtcctctatgacctcagcaagctctgc
ttccgaaagaggacccatgtgaaatttccactcaaccctgagggcatggaagaactagaa
gtggaattcttgctggaggagagcccagctccacctgaaagcctcctcaccaatggcgta
ctagtgtctagacaagtttcctgcctggaagtccatgtgaagcataaaaaacagaagaag
aatcgaaagagaaaacaactaagcgtgacagtgaatgaatcctatgaaaacacccagtac
atctcaccctgctacagctccagcaaccaatgcccagatcttgccttcttccactacacc
aaatacttccagccccaaatgcacgtggaagtgcccaggagtcgatggacctgtgggctt
tcctgctgctgtggtacccataaaggaaaccgttctgtctgcatgtccttggactgcctc
ccagatggacaagagttgacagtaccgatgaatgaaaattgtgatttacatgtgacagcc
aaagactgccctgatgagttgaatgtgaggctgggttacagtctatgctcagaggagctg
gagttcctgcagaagcggaaggtgattgtagcagaagccctgaagcaggtgttgcagctg
gagcagaatcttcaagacaatgaggtgcctctggtggcgatcatggccacagggggtggc
ttgagatcgatgacctccatgtatggccacctgttgggtcttcaaaagctgaacatcctg
aactgtaccagctacatcacaggcctttcaggtgcaagttggaccatgtccaacttatac
aaagacgctgactggtcctccaaaaacctggagaaggccatccaggaggctcgcagacat
gctgtcaaaaacaagatcccttcactttgccctgaacaactcggatactaccagcagaac
ctgaaacaaaggagccaagaaggctacagagttaccttcacagacctgtggggtttattg
atcgagtcctttttgggggatgagaaatatgaagggaagttgtcatggcaaaaagaagct
ctgtgccagggccagaatcccctcccaatctacctcaccatcaatgtgaaggatgatgta
agcaaccaggatttcagagaatgggtggagttcaccccctacgaagtgggattccagaaa
tatggagcctatgtccccacggaatattttggctctgaattctacatgggacgattgatg
aagaggatccccgagtcccggctatgttacttgctaggcctgtggagcagcatcttctcc
ctgaacatgcttgatgcctggaatctgtcccacagttcagaggaatttttccacaggtgg
acaagagaaaaagtgcacgatattgaggatgaacctttattgcctgaaatccccaagtgc
gacacaaacgtcctggagacaacagtggtgttacctgccacaaagctagccaatactcta
cgggatgtcctcacctaccgagcctttgtgtctcagttccacaacttcctccagggcctg
cagcttcacacagactatctgcaaaatagccagttcaccacctggaaagacacagtgctg
gattgtttcccaaaccgtctgacacaagctgagagccatctctgcctgctggatactgcg
ttcttcatcaactccagttacccacccctcctgagaccggagaggaaagctgacatcatc
atacatcttaattactgtgcaggttcccagataaagcccctaaaacagacctgtgagtac
tgcaaagtgcagaatatccccttccccaaatacagtgtgaaagaagaaggtgaagaacac
ttaaaggagtgttacctgttgacacctgatgaagatgacccagatgccccaatagtactg
ttctttccactcatcaatggctctttccaaaagtataaagccccaggtgtggagcgtagc
ccagaggagatggaggatggacatgttgatatctacagccacaatactccctatgccacc
aaggaggtaacttacacggagtctgcttttgaccgaatggtcaacctctctgaatacaac
atcctgaataacgcagacacgatccttcaaggcttacgcctagctgtggaaaggaagaag
cagttcaagaaagcgtgttcatcgtaa

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