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Database: PDB
Entry: 1EGF
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Original site: 1EGF 
HEADER    GROWTH FACTOR                           01-OCT-91   1EGF              
TITLE     SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR                  
TITLE    2 DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY                 
TITLE    3 MINIMIZATION WITH RESTRAINTS                                         
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: EPIDERMAL GROWTH FACTOR;                                   
COMPND   3 CHAIN: A;                                                            
COMPND   4 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: MUS MUSCULUS;                                   
SOURCE   3 ORGANISM_COMMON: HOUSE MOUSE;                                        
SOURCE   4 ORGANISM_TAXID: 10090                                                
KEYWDS    GROWTH FACTOR                                                         
EXPDTA    SOLUTION NMR                                                          
NUMMDL    16                                                                    
AUTHOR    G.T.MONTELIONE,K.WUTHRICH,H.A.SCHERAGA                                
REVDAT   2   24-FEB-09 1EGF    1       VERSN                                    
REVDAT   1   31-JAN-94 1EGF    0                                                
JRNL        AUTH   G.T.MONTELIONE,K.WUTHRICH,A.W.BURGESS,E.C.NICE,              
JRNL        AUTH 2 G.WAGNER,K.D.GIBSON,H.A.SCHERAGA                             
JRNL        TITL   SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH                
JRNL        TITL 2 FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED            
JRNL        TITL 3 BY ENERGY MINIMIZATION WITH RESTRAINTS.                      
JRNL        REF    BIOCHEMISTRY                  V.  31   236 1992              
JRNL        REFN                   ISSN 0006-2960                               
JRNL        PMID   1731873                                                      
JRNL        DOI    10.1021/BI00116A033                                          
REMARK   1                                                                      
REMARK   1 REFERENCE 1                                                          
REMARK   1  AUTH   G.T.MONTELIONE,K.WUTHRICH,H.A.SCHERAGA                       
REMARK   1  TITL   SEQUENCE-SPECIFIC 1H NMR ASSIGNMENTS AND                     
REMARK   1  TITL 2 IDENTIFICATION OF SLOWLY EXCHANGING AMIDE PROTONS            
REMARK   1  TITL 3 IN MURINE EPIDERMAL GROWTH FACTOR                            
REMARK   1  REF    BIOCHEMISTRY                  V.  27  2235 1988              
REMARK   1  REFN                   ISSN 0006-2960                               
REMARK   1 REFERENCE 2                                                          
REMARK   1  AUTH   G.T.MONTELIONE,K.WUTHRICH,E.C.NICE,A.W.BURGESS,              
REMARK   1  AUTH 2 H.A.SCHERAGA                                                 
REMARK   1  TITL   SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH                
REMARK   1  TITL 2 FACTOR: DETERMINATION OF THE POLYPEPTIDE BACKBONE            
REMARK   1  TITL 3 CHAIN-FOLD BY NUCLEAR MAGNETIC RESONANCE AND                 
REMARK   1  TITL 4 DISTANCE GEOMETRY                                            
REMARK   1  REF    PROC.NATL.ACAD.SCI.USA        V.  84  5226 1987              
REMARK   1  REFN                   ISSN 0027-8424                               
REMARK   1 REFERENCE 3                                                          
REMARK   1  AUTH   G.T.MONTELIONE,K.WUTHRICH,E.C.NICE,A.W.BURGESS,              
REMARK   1  AUTH 2 H.A.SCHERAGA                                                 
REMARK   1  TITL   IDENTIFICATION OF TWO ANTI-PARALLEL BETA-SHEET               
REMARK   1  TITL 2 CONFORMATIONS IN THE SOLUTION STRUCTURE OF MURINE            
REMARK   1  TITL 3 EPIDERMAL GROWTH FACTOR BY PROTON MAGNETIC                   
REMARK   1  TITL 4 RESONANCE                                                    
REMARK   1  REF    PROC.NATL.ACAD.SCI.USA        V.  83  8594 1986              
REMARK   1  REFN                   ISSN 0027-8424                               
REMARK   2                                                                      
REMARK   2 RESOLUTION. NOT APPLICABLE.                                          
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : DISMAN                                               
REMARK   3   AUTHORS     : BRAUN,GO                                             
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: NULL                                      
REMARK   4                                                                      
REMARK   4 1EGF COMPLIES WITH FORMAT V. 3.15, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY BNL.                                
REMARK 210                                                                      
REMARK 210 EXPERIMENTAL DETAILS                                                 
REMARK 210  EXPERIMENT TYPE                : NMR                                
REMARK 210  TEMPERATURE           (KELVIN) : NULL                               
REMARK 210  PH                             : NULL                               
REMARK 210  IONIC STRENGTH                 : NULL                               
REMARK 210  PRESSURE                       : NULL                               
REMARK 210  SAMPLE CONTENTS                : NULL                               
REMARK 210                                                                      
REMARK 210  NMR EXPERIMENTS CONDUCTED      : NULL                               
REMARK 210  SPECTROMETER FIELD STRENGTH    : NULL                               
REMARK 210  SPECTROMETER MODEL             : NULL                               
REMARK 210  SPECTROMETER MANUFACTURER      : NULL                               
REMARK 210                                                                      
REMARK 210  STRUCTURE DETERMINATION.                                            
REMARK 210   SOFTWARE USED                 : NULL                               
REMARK 210   METHOD USED                   : NULL                               
REMARK 210                                                                      
REMARK 210 CONFORMERS, NUMBER CALCULATED   : NULL                               
REMARK 210 CONFORMERS, NUMBER SUBMITTED    : 16                                 
REMARK 210 CONFORMERS, SELECTION CRITERIA  : NULL                               
REMARK 210                                                                      
REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : NULL                
REMARK 210                                                                      
REMARK 210 REMARK: NULL                                                         
REMARK 215                                                                      
REMARK 215 NMR STUDY                                                            
REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION           
REMARK 215 NMR DATA.  PROTEIN DATA BANK CONVENTIONS REQUIRE THAT                
REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON              
REMARK 215 THESE RECORDS ARE MEANINGLESS.                                       
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500  1 CYS A   6       89.11   -178.07                                   
REMARK 500  1 TYR A  10      -98.72    -92.26                                   
REMARK 500  1 ASP A  11       88.14    153.89                                   
REMARK 500  1 TYR A  13      -34.97    -34.48                                   
REMARK 500  1 ASN A  16      -50.93     80.33                                   
REMARK 500  1 LEU A  26       24.08   -158.08                                   
REMARK 500  1 CYS A  33     -144.47   -111.32                                   
REMARK 500  1 ILE A  35      132.51    -37.98                                   
REMARK 500  1 SER A  38     -164.81    179.88                                   
REMARK 500  1 ARG A  41      -87.68   -166.43                                   
REMARK 500  1 CYS A  42       18.21   -148.89                                   
REMARK 500  1 THR A  44       69.43    -66.21                                   
REMARK 500  1 ARG A  45       55.83    -68.56                                   
REMARK 500  1 LEU A  47     -114.64    -82.82                                   
REMARK 500  1 ARG A  48       87.96     71.35                                   
REMARK 500  1 TRP A  49       99.66    -42.82                                   
REMARK 500  1 TRP A  50       65.05   -109.28                                   
REMARK 500  2 CYS A   6       94.94   -168.60                                   
REMARK 500  2 ASP A  11       80.42     58.10                                   
REMARK 500  2 ASN A  16       56.42     21.81                                   
REMARK 500  2 LEU A  26       22.74   -154.49                                   
REMARK 500  2 THR A  30     -166.52   -129.84                                   
REMARK 500  2 CYS A  33     -160.89    -64.45                                   
REMARK 500  2 ASP A  40      -59.97     70.31                                   
REMARK 500  2 ARG A  41      -71.30   -100.20                                   
REMARK 500  2 CYS A  42       42.79    157.36                                   
REMARK 500  2 ASP A  46     -148.02    -80.92                                   
REMARK 500  2 LEU A  47      -95.26   -131.70                                   
REMARK 500  2 ARG A  48       75.04     77.79                                   
REMARK 500  2 TRP A  49       94.48     42.06                                   
REMARK 500  3 CYS A   6      101.42   -179.70                                   
REMARK 500  3 ASN A  16      -55.83     70.02                                   
REMARK 500  3 GLU A  24     -174.74     46.75                                   
REMARK 500  3 SER A  25      -33.68     83.60                                   
REMARK 500  3 LEU A  26       12.94   -145.75                                   
REMARK 500  3 CYS A  33     -106.67    -84.03                                   
REMARK 500  3 SER A  38     -140.68   -177.65                                   
REMARK 500  3 ASP A  40      -35.40     87.92                                   
REMARK 500  3 ARG A  41      -85.93   -128.26                                   
REMARK 500  3 CYS A  42       35.49    176.86                                   
REMARK 500  3 ASP A  46      -91.73    -40.43                                   
REMARK 500  3 ARG A  48       51.05     85.23                                   
REMARK 500  3 GLU A  51      -55.52   -141.14                                   
REMARK 500  4 CYS A   6       97.61    177.90                                   
REMARK 500  4 ASP A  11       47.56   -105.04                                   
REMARK 500  4 LEU A  26       21.02   -155.03                                   
REMARK 500  4 THR A  30     -165.17   -122.27                                   
REMARK 500  4 CYS A  33     -159.36    -76.27                                   
REMARK 500  4 ASP A  40      -66.83     67.89                                   
REMARK 500  4 ARG A  41      -71.77    -96.99                                   
REMARK 500  4 CYS A  42       46.19    156.94                                   
REMARK 500  4 LEU A  47     -161.03   -161.08                                   
REMARK 500  4 ARG A  48       51.83   -144.57                                   
REMARK 500  4 TRP A  49       80.29    -64.24                                   
REMARK 500  4 TRP A  50      -54.16   -164.66                                   
REMARK 500  4 LEU A  52      -54.83   -134.71                                   
REMARK 500  5 CYS A   6       96.88    179.00                                   
REMARK 500  5 ASP A  11       79.71     60.87                                   
REMARK 500  5 ASN A  16       63.39     32.94                                   
REMARK 500  5 GLU A  24      -57.46     68.08                                   
REMARK 500  5 ASP A  27       29.26     43.65                                   
REMARK 500  5 THR A  30     -166.32    -76.98                                   
REMARK 500  5 CYS A  33     -157.98    -59.76                                   
REMARK 500  5 SER A  38     -179.13   -170.30                                   
REMARK 500  5 ASP A  40      -60.66     71.03                                   
REMARK 500  5 ARG A  41      -84.09    -86.65                                   
REMARK 500  5 CYS A  42       94.71    153.95                                   
REMARK 500  5 GLN A  43      -39.06   -156.93                                   
REMARK 500  5 ASP A  46     -167.74   -102.12                                   
REMARK 500  5 LEU A  47      -96.67     56.54                                   
REMARK 500  6 CYS A   6       78.76   -157.23                                   
REMARK 500  6 ASP A  11       70.13     49.09                                   
REMARK 500  6 ASN A  16      -53.79     74.48                                   
REMARK 500  6 SER A  25      -31.88     87.36                                   
REMARK 500  6 LEU A  26       15.55   -146.67                                   
REMARK 500  6 CYS A  33     -152.70   -127.45                                   
REMARK 500  6 ARG A  41      -78.75   -144.11                                   
REMARK 500  6 CYS A  42       66.90    169.87                                   
REMARK 500  6 LEU A  47       72.45     41.04                                   
REMARK 500  6 ARG A  48       91.49    161.32                                   
REMARK 500  7 CYS A   6      107.13    178.03                                   
REMARK 500  7 TYR A  13      -43.85     67.86                                   
REMARK 500  7 ASN A  16       58.35     32.25                                   
REMARK 500  7 LEU A  26       25.09   -159.70                                   
REMARK 500  7 CYS A  33     -118.01    -84.89                                   
REMARK 500  7 SER A  38     -161.57   -167.04                                   
REMARK 500  7 ASP A  40      -30.94    -37.66                                   
REMARK 500  7 ARG A  41      -64.12   -132.30                                   
REMARK 500  7 CYS A  42       22.76    173.69                                   
REMARK 500  7 THR A  44       62.76    -66.21                                   
REMARK 500  7 ASP A  46     -145.48    -60.15                                   
REMARK 500  8 CYS A   6      100.41   -172.40                                   
REMARK 500  8 ASP A  11       78.31     59.25                                   
REMARK 500  8 MET A  21      113.99   -160.96                                   
REMARK 500  8 CYS A  33     -153.67    -88.98                                   
REMARK 500  8 ILE A  35      158.38    -45.86                                   
REMARK 500  8 TYR A  37      103.42   -161.71                                   
REMARK 500  8 ASP A  40      117.29     60.96                                   
REMARK 500  8 CYS A  42       87.84     65.20                                   
REMARK 500  8 THR A  44       98.57    -65.46                                   
REMARK 500  8 ASP A  46     -153.53     40.93                                   
REMARK 500  8 LEU A  47       72.60     49.06                                   
REMARK 500  8 ARG A  48       81.89    169.13                                   
REMARK 500  8 TRP A  49      140.25     59.78                                   
REMARK 500  8 TRP A  50      -97.81   -172.56                                   
REMARK 500  9 CYS A   6      108.73    172.56                                   
REMARK 500  9 ASP A  11       46.60    -99.21                                   
REMARK 500  9 LEU A  26       24.08   -157.20                                   
REMARK 500  9 CYS A  33     -121.41    -60.30                                   
REMARK 500  9 VAL A  34     -155.61   -147.35                                   
REMARK 500  9 SER A  38     -160.44   -169.63                                   
REMARK 500  9 ARG A  41      -87.03   -142.06                                   
REMARK 500  9 CYS A  42       33.58    176.88                                   
REMARK 500  9 ASP A  46      -71.64    -82.55                                   
REMARK 500  9 ARG A  48       59.22   -179.80                                   
REMARK 500 10 CYS A   6      100.82   -178.44                                   
REMARK 500 10 ASP A  11       75.60     49.70                                   
REMARK 500 10 GLU A  24      170.24     52.78                                   
REMARK 500 10 SER A  25      -25.03     77.18                                   
REMARK 500 10 LEU A  26       15.50   -143.20                                   
REMARK 500 10 ASP A  27       22.30     49.05                                   
REMARK 500 10 CYS A  33     -150.15   -119.94                                   
REMARK 500 10 CYS A  42       73.18     48.07                                   
REMARK 500 10 ASP A  46     -144.32    -66.13                                   
REMARK 500 10 LEU A  47      -44.72   -150.56                                   
REMARK 500 10 ARG A  48       68.75   -172.05                                   
REMARK 500 10 GLU A  51      -50.99   -132.48                                   
REMARK 500 11 CYS A   6      119.11    168.72                                   
REMARK 500 11 TYR A  13       13.44     58.76                                   
REMARK 500 11 ASN A  16      -59.92     65.32                                   
REMARK 500 11 SER A  25      -29.83     88.44                                   
REMARK 500 11 LEU A  26       18.07   -151.79                                   
REMARK 500 11 CYS A  33     -145.37    -78.41                                   
REMARK 500 11 ASP A  40       38.97     37.96                                   
REMARK 500 11 ARG A  41      -27.69    177.08                                   
REMARK 500 11 CYS A  42       79.49     81.76                                   
REMARK 500 11 GLN A  43      -37.70   -134.49                                   
REMARK 500 11 ASP A  46      -68.51   -130.38                                   
REMARK 500 11 LEU A  47      116.32    -10.85                                   
REMARK 500 11 ARG A  48       62.38   -160.57                                   
REMARK 500 11 GLU A  51      -50.81   -167.87                                   
REMARK 500 12 CYS A   6       94.74   -174.80                                   
REMARK 500 12 TYR A  13       20.68     47.15                                   
REMARK 500 12 ASN A  16      -53.34     76.78                                   
REMARK 500 12 SER A  25      -30.20     88.70                                   
REMARK 500 12 LEU A  26       17.48   -150.46                                   
REMARK 500 12 ASP A  40      117.83    -33.56                                   
REMARK 500 12 ARG A  41       16.06     85.85                                   
REMARK 500 12 THR A  44       89.62    -69.49                                   
REMARK 500 12 ARG A  48       50.92     94.04                                   
REMARK 500 12 GLU A  51      -55.93   -164.11                                   
REMARK 500 13 CYS A   6      111.02    176.05                                   
REMARK 500 13 SER A   8       -6.17     95.05                                   
REMARK 500 13 TYR A  10      -89.08    -85.38                                   
REMARK 500 13 ASP A  11       89.71    157.33                                   
REMARK 500 13 ASN A  16      -54.15     82.11                                   
REMARK 500 13 LEU A  26       26.18   -161.86                                   
REMARK 500 13 CYS A  33     -147.24    -61.13                                   
REMARK 500 13 ARG A  41      -82.52   -128.40                                   
REMARK 500 13 CYS A  42       26.99    172.15                                   
REMARK 500 13 ASP A  46     -145.58    -64.19                                   
REMARK 500 13 LEU A  47      -51.06   -121.82                                   
REMARK 500 13 ARG A  48       74.15    174.16                                   
REMARK 500 13 TRP A  49       47.22    -88.44                                   
REMARK 500 14 CYS A   6       82.99   -177.07                                   
REMARK 500 14 ASP A  11       55.58   -113.77                                   
REMARK 500 14 ASN A  16       23.05     48.16                                   
REMARK 500 14 LEU A  26       31.98   -164.04                                   
REMARK 500 14 ASP A  27       28.88     46.10                                   
REMARK 500 14 CYS A  33     -135.36    -75.12                                   
REMARK 500 14 SER A  38     -154.23   -164.78                                   
REMARK 500 14 ASP A  40      108.14   -177.74                                   
REMARK 500 14 CYS A  42       69.82     68.32                                   
REMARK 500 14 THR A  44       72.87    -65.72                                   
REMARK 500 14 ASP A  46     -143.64    -71.20                                   
REMARK 500 14 ARG A  48       68.08     75.78                                   
REMARK 500 15 CYS A   6       89.33    157.43                                   
REMARK 500 15 SER A   8       15.25     47.39                                   
REMARK 500 15 SER A   9       22.87     46.86                                   
REMARK 500 15 TYR A  10       38.36     31.39                                   
REMARK 500 15 ASP A  11       74.29     61.98                                   
REMARK 500 15 ASP A  27       24.47     44.18                                   
REMARK 500 15 CYS A  31      118.89   -162.56                                   
REMARK 500 15 CYS A  33     -147.47    -67.01                                   
REMARK 500 15 SER A  38     -168.79   -161.27                                   
REMARK 500 15 ASP A  40       48.67     38.09                                   
REMARK 500 15 ARG A  41      -30.37    174.60                                   
REMARK 500 15 CYS A  42       20.33     83.70                                   
REMARK 500 15 LEU A  47       81.07     38.28                                   
REMARK 500 15 ARG A  48       31.54   -164.49                                   
REMARK 500 15 TRP A  50      -50.31   -139.76                                   
REMARK 500 16 CYS A   6       95.94   -174.78                                   
REMARK 500 16 ASP A  11       72.66     53.67                                   
REMARK 500 16 SER A  25      -29.59     88.28                                   
REMARK 500 16 LEU A  26       17.99   -151.30                                   
REMARK 500 16 CYS A  33     -159.43   -119.38                                   
REMARK 500 16 ILE A  35      138.59    -34.47                                   
REMARK 500 16 ASP A  40      -32.65    -36.35                                   
REMARK 500 16 CYS A  42       38.74    153.43                                   
REMARK 500 16 ASP A  46      -34.31    -32.99                                   
REMARK 500 16 LEU A  47       60.51    -65.96                                   
REMARK 500 16 ARG A  48       82.31    164.75                                   
REMARK 500 16 TRP A  49     -168.90    -55.21                                   
REMARK 500 16 TRP A  50      -67.16   -158.49                                   
REMARK 500 16 GLU A  51      -97.83   -155.06                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: PLANAR GROUPS                                              
REMARK 500                                                                      
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL                 
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE                    
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN                    
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS                        
REMARK 500 AN RMSD GREATER THAN THIS VALUE                                      
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        RMS     TYPE                                    
REMARK 500  1 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  1 ARG A  45         0.28    SIDE_CHAIN                              
REMARK 500  1 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500  1 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500  2 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  2 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  2 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500  2 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500  3 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  3 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  3 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500  3 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500  4 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  4 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  4 ARG A  48         0.29    SIDE_CHAIN                              
REMARK 500  4 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500  5 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  5 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  5 ARG A  48         0.29    SIDE_CHAIN                              
REMARK 500  5 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500  6 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  6 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  6 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500  6 ARG A  53         0.29    SIDE_CHAIN                              
REMARK 500  7 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  7 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  7 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500  7 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500  8 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  8 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  8 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500  8 ARG A  53         0.26    SIDE_CHAIN                              
REMARK 500  9 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500  9 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500  9 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500  9 ARG A  53         0.29    SIDE_CHAIN                              
REMARK 500 10 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500 10 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500 10 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500 10 ARG A  53         0.27    SIDE_CHAIN                              
REMARK 500 11 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500 11 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500 11 ARG A  48         0.28    SIDE_CHAIN                              
REMARK 500 11 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500 12 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500 12 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500 12 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500 12 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500 13 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500 13 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500 13 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500 13 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500 14 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500 14 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500 14 ARG A  48         0.28    SIDE_CHAIN                              
REMARK 500 14 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500 15 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500 15 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500 15 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500 15 ARG A  53         0.30    SIDE_CHAIN                              
REMARK 500 16 ARG A  41         0.30    SIDE_CHAIN                              
REMARK 500 16 ARG A  45         0.30    SIDE_CHAIN                              
REMARK 500 16 ARG A  48         0.30    SIDE_CHAIN                              
REMARK 500 16 ARG A  53         0.17    SIDE_CHAIN                              
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
DBREF  1EGF A    1    53  UNP    P01132   EGF_MOUSE      977   1029             
SEQRES   1 A   53  ASN SER TYR PRO GLY CYS PRO SER SER TYR ASP GLY TYR          
SEQRES   2 A   53  CYS LEU ASN GLY GLY VAL CYS MET HIS ILE GLU SER LEU          
SEQRES   3 A   53  ASP SER TYR THR CYS ASN CYS VAL ILE GLY TYR SER GLY          
SEQRES   4 A   53  ASP ARG CYS GLN THR ARG ASP LEU ARG TRP TRP GLU LEU          
SEQRES   5 A   53  ARG                                                          
SHEET    1   A 3 SER A   2  TYR A   3  0                                        
SHEET    2   A 3 VAL A  19  ILE A  23 -1  O  HIS A  22   N  TYR A   3           
SHEET    3   A 3 TYR A  29  ASN A  32 -1  N  THR A  30   O  MET A  21           
SSBOND   1 CYS A    6    CYS A   20                          1555   1555  1.92  
SSBOND   2 CYS A   14    CYS A   31                          1555   1555  1.53  
SSBOND   3 CYS A   33    CYS A   42                          1555   1555  1.86  
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
MODEL        1                                                                  
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
DBGET integrated database retrieval system