HEADER GROWTH FACTOR 01-OCT-91 1EGF
TITLE SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR
TITLE 2 DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY
TITLE 3 MINIMIZATION WITH RESTRAINTS
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: EPIDERMAL GROWTH FACTOR;
COMPND 3 CHAIN: A;
COMPND 4 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS;
SOURCE 3 ORGANISM_COMMON: HOUSE MOUSE;
SOURCE 4 ORGANISM_TAXID: 10090
KEYWDS GROWTH FACTOR
EXPDTA SOLUTION NMR
NUMMDL 16
AUTHOR G.T.MONTELIONE,K.WUTHRICH,H.A.SCHERAGA
REVDAT 2 24-FEB-09 1EGF 1 VERSN
REVDAT 1 31-JAN-94 1EGF 0
JRNL AUTH G.T.MONTELIONE,K.WUTHRICH,A.W.BURGESS,E.C.NICE,
JRNL AUTH 2 G.WAGNER,K.D.GIBSON,H.A.SCHERAGA
JRNL TITL SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH
JRNL TITL 2 FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED
JRNL TITL 3 BY ENERGY MINIMIZATION WITH RESTRAINTS.
JRNL REF BIOCHEMISTRY V. 31 236 1992
JRNL REFN ISSN 0006-2960
JRNL PMID 1731873
JRNL DOI 10.1021/BI00116A033
REMARK 1
REMARK 1 REFERENCE 1
REMARK 1 AUTH G.T.MONTELIONE,K.WUTHRICH,H.A.SCHERAGA
REMARK 1 TITL SEQUENCE-SPECIFIC 1H NMR ASSIGNMENTS AND
REMARK 1 TITL 2 IDENTIFICATION OF SLOWLY EXCHANGING AMIDE PROTONS
REMARK 1 TITL 3 IN MURINE EPIDERMAL GROWTH FACTOR
REMARK 1 REF BIOCHEMISTRY V. 27 2235 1988
REMARK 1 REFN ISSN 0006-2960
REMARK 1 REFERENCE 2
REMARK 1 AUTH G.T.MONTELIONE,K.WUTHRICH,E.C.NICE,A.W.BURGESS,
REMARK 1 AUTH 2 H.A.SCHERAGA
REMARK 1 TITL SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH
REMARK 1 TITL 2 FACTOR: DETERMINATION OF THE POLYPEPTIDE BACKBONE
REMARK 1 TITL 3 CHAIN-FOLD BY NUCLEAR MAGNETIC RESONANCE AND
REMARK 1 TITL 4 DISTANCE GEOMETRY
REMARK 1 REF PROC.NATL.ACAD.SCI.USA V. 84 5226 1987
REMARK 1 REFN ISSN 0027-8424
REMARK 1 REFERENCE 3
REMARK 1 AUTH G.T.MONTELIONE,K.WUTHRICH,E.C.NICE,A.W.BURGESS,
REMARK 1 AUTH 2 H.A.SCHERAGA
REMARK 1 TITL IDENTIFICATION OF TWO ANTI-PARALLEL BETA-SHEET
REMARK 1 TITL 2 CONFORMATIONS IN THE SOLUTION STRUCTURE OF MURINE
REMARK 1 TITL 3 EPIDERMAL GROWTH FACTOR BY PROTON MAGNETIC
REMARK 1 TITL 4 RESONANCE
REMARK 1 REF PROC.NATL.ACAD.SCI.USA V. 83 8594 1986
REMARK 1 REFN ISSN 0027-8424
REMARK 2
REMARK 2 RESOLUTION. NOT APPLICABLE.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 PROGRAM : DISMAN
REMARK 3 AUTHORS : BRAUN,GO
REMARK 3
REMARK 3 OTHER REFINEMENT REMARKS: NULL
REMARK 4
REMARK 4 1EGF COMPLIES WITH FORMAT V. 3.15, 01-DEC-08
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY BNL.
REMARK 210
REMARK 210 EXPERIMENTAL DETAILS
REMARK 210 EXPERIMENT TYPE : NMR
REMARK 210 TEMPERATURE (KELVIN) : NULL
REMARK 210 PH : NULL
REMARK 210 IONIC STRENGTH : NULL
REMARK 210 PRESSURE : NULL
REMARK 210 SAMPLE CONTENTS : NULL
REMARK 210
REMARK 210 NMR EXPERIMENTS CONDUCTED : NULL
REMARK 210 SPECTROMETER FIELD STRENGTH : NULL
REMARK 210 SPECTROMETER MODEL : NULL
REMARK 210 SPECTROMETER MANUFACTURER : NULL
REMARK 210
REMARK 210 STRUCTURE DETERMINATION.
REMARK 210 SOFTWARE USED : NULL
REMARK 210 METHOD USED : NULL
REMARK 210
REMARK 210 CONFORMERS, NUMBER CALCULATED : NULL
REMARK 210 CONFORMERS, NUMBER SUBMITTED : 16
REMARK 210 CONFORMERS, SELECTION CRITERIA : NULL
REMARK 210
REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : NULL
REMARK 210
REMARK 210 REMARK: NULL
REMARK 215
REMARK 215 NMR STUDY
REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION
REMARK 215 NMR DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE THAT
REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON
REMARK 215 THESE RECORDS ARE MEANINGLESS.
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 1 CYS A 6 89.11 -178.07
REMARK 500 1 TYR A 10 -98.72 -92.26
REMARK 500 1 ASP A 11 88.14 153.89
REMARK 500 1 TYR A 13 -34.97 -34.48
REMARK 500 1 ASN A 16 -50.93 80.33
REMARK 500 1 LEU A 26 24.08 -158.08
REMARK 500 1 CYS A 33 -144.47 -111.32
REMARK 500 1 ILE A 35 132.51 -37.98
REMARK 500 1 SER A 38 -164.81 179.88
REMARK 500 1 ARG A 41 -87.68 -166.43
REMARK 500 1 CYS A 42 18.21 -148.89
REMARK 500 1 THR A 44 69.43 -66.21
REMARK 500 1 ARG A 45 55.83 -68.56
REMARK 500 1 LEU A 47 -114.64 -82.82
REMARK 500 1 ARG A 48 87.96 71.35
REMARK 500 1 TRP A 49 99.66 -42.82
REMARK 500 1 TRP A 50 65.05 -109.28
REMARK 500 2 CYS A 6 94.94 -168.60
REMARK 500 2 ASP A 11 80.42 58.10
REMARK 500 2 ASN A 16 56.42 21.81
REMARK 500 2 LEU A 26 22.74 -154.49
REMARK 500 2 THR A 30 -166.52 -129.84
REMARK 500 2 CYS A 33 -160.89 -64.45
REMARK 500 2 ASP A 40 -59.97 70.31
REMARK 500 2 ARG A 41 -71.30 -100.20
REMARK 500 2 CYS A 42 42.79 157.36
REMARK 500 2 ASP A 46 -148.02 -80.92
REMARK 500 2 LEU A 47 -95.26 -131.70
REMARK 500 2 ARG A 48 75.04 77.79
REMARK 500 2 TRP A 49 94.48 42.06
REMARK 500 3 CYS A 6 101.42 -179.70
REMARK 500 3 ASN A 16 -55.83 70.02
REMARK 500 3 GLU A 24 -174.74 46.75
REMARK 500 3 SER A 25 -33.68 83.60
REMARK 500 3 LEU A 26 12.94 -145.75
REMARK 500 3 CYS A 33 -106.67 -84.03
REMARK 500 3 SER A 38 -140.68 -177.65
REMARK 500 3 ASP A 40 -35.40 87.92
REMARK 500 3 ARG A 41 -85.93 -128.26
REMARK 500 3 CYS A 42 35.49 176.86
REMARK 500 3 ASP A 46 -91.73 -40.43
REMARK 500 3 ARG A 48 51.05 85.23
REMARK 500 3 GLU A 51 -55.52 -141.14
REMARK 500 4 CYS A 6 97.61 177.90
REMARK 500 4 ASP A 11 47.56 -105.04
REMARK 500 4 LEU A 26 21.02 -155.03
REMARK 500 4 THR A 30 -165.17 -122.27
REMARK 500 4 CYS A 33 -159.36 -76.27
REMARK 500 4 ASP A 40 -66.83 67.89
REMARK 500 4 ARG A 41 -71.77 -96.99
REMARK 500 4 CYS A 42 46.19 156.94
REMARK 500 4 LEU A 47 -161.03 -161.08
REMARK 500 4 ARG A 48 51.83 -144.57
REMARK 500 4 TRP A 49 80.29 -64.24
REMARK 500 4 TRP A 50 -54.16 -164.66
REMARK 500 4 LEU A 52 -54.83 -134.71
REMARK 500 5 CYS A 6 96.88 179.00
REMARK 500 5 ASP A 11 79.71 60.87
REMARK 500 5 ASN A 16 63.39 32.94
REMARK 500 5 GLU A 24 -57.46 68.08
REMARK 500 5 ASP A 27 29.26 43.65
REMARK 500 5 THR A 30 -166.32 -76.98
REMARK 500 5 CYS A 33 -157.98 -59.76
REMARK 500 5 SER A 38 -179.13 -170.30
REMARK 500 5 ASP A 40 -60.66 71.03
REMARK 500 5 ARG A 41 -84.09 -86.65
REMARK 500 5 CYS A 42 94.71 153.95
REMARK 500 5 GLN A 43 -39.06 -156.93
REMARK 500 5 ASP A 46 -167.74 -102.12
REMARK 500 5 LEU A 47 -96.67 56.54
REMARK 500 6 CYS A 6 78.76 -157.23
REMARK 500 6 ASP A 11 70.13 49.09
REMARK 500 6 ASN A 16 -53.79 74.48
REMARK 500 6 SER A 25 -31.88 87.36
REMARK 500 6 LEU A 26 15.55 -146.67
REMARK 500 6 CYS A 33 -152.70 -127.45
REMARK 500 6 ARG A 41 -78.75 -144.11
REMARK 500 6 CYS A 42 66.90 169.87
REMARK 500 6 LEU A 47 72.45 41.04
REMARK 500 6 ARG A 48 91.49 161.32
REMARK 500 7 CYS A 6 107.13 178.03
REMARK 500 7 TYR A 13 -43.85 67.86
REMARK 500 7 ASN A 16 58.35 32.25
REMARK 500 7 LEU A 26 25.09 -159.70
REMARK 500 7 CYS A 33 -118.01 -84.89
REMARK 500 7 SER A 38 -161.57 -167.04
REMARK 500 7 ASP A 40 -30.94 -37.66
REMARK 500 7 ARG A 41 -64.12 -132.30
REMARK 500 7 CYS A 42 22.76 173.69
REMARK 500 7 THR A 44 62.76 -66.21
REMARK 500 7 ASP A 46 -145.48 -60.15
REMARK 500 8 CYS A 6 100.41 -172.40
REMARK 500 8 ASP A 11 78.31 59.25
REMARK 500 8 MET A 21 113.99 -160.96
REMARK 500 8 CYS A 33 -153.67 -88.98
REMARK 500 8 ILE A 35 158.38 -45.86
REMARK 500 8 TYR A 37 103.42 -161.71
REMARK 500 8 ASP A 40 117.29 60.96
REMARK 500 8 CYS A 42 87.84 65.20
REMARK 500 8 THR A 44 98.57 -65.46
REMARK 500 8 ASP A 46 -153.53 40.93
REMARK 500 8 LEU A 47 72.60 49.06
REMARK 500 8 ARG A 48 81.89 169.13
REMARK 500 8 TRP A 49 140.25 59.78
REMARK 500 8 TRP A 50 -97.81 -172.56
REMARK 500 9 CYS A 6 108.73 172.56
REMARK 500 9 ASP A 11 46.60 -99.21
REMARK 500 9 LEU A 26 24.08 -157.20
REMARK 500 9 CYS A 33 -121.41 -60.30
REMARK 500 9 VAL A 34 -155.61 -147.35
REMARK 500 9 SER A 38 -160.44 -169.63
REMARK 500 9 ARG A 41 -87.03 -142.06
REMARK 500 9 CYS A 42 33.58 176.88
REMARK 500 9 ASP A 46 -71.64 -82.55
REMARK 500 9 ARG A 48 59.22 -179.80
REMARK 500 10 CYS A 6 100.82 -178.44
REMARK 500 10 ASP A 11 75.60 49.70
REMARK 500 10 GLU A 24 170.24 52.78
REMARK 500 10 SER A 25 -25.03 77.18
REMARK 500 10 LEU A 26 15.50 -143.20
REMARK 500 10 ASP A 27 22.30 49.05
REMARK 500 10 CYS A 33 -150.15 -119.94
REMARK 500 10 CYS A 42 73.18 48.07
REMARK 500 10 ASP A 46 -144.32 -66.13
REMARK 500 10 LEU A 47 -44.72 -150.56
REMARK 500 10 ARG A 48 68.75 -172.05
REMARK 500 10 GLU A 51 -50.99 -132.48
REMARK 500 11 CYS A 6 119.11 168.72
REMARK 500 11 TYR A 13 13.44 58.76
REMARK 500 11 ASN A 16 -59.92 65.32
REMARK 500 11 SER A 25 -29.83 88.44
REMARK 500 11 LEU A 26 18.07 -151.79
REMARK 500 11 CYS A 33 -145.37 -78.41
REMARK 500 11 ASP A 40 38.97 37.96
REMARK 500 11 ARG A 41 -27.69 177.08
REMARK 500 11 CYS A 42 79.49 81.76
REMARK 500 11 GLN A 43 -37.70 -134.49
REMARK 500 11 ASP A 46 -68.51 -130.38
REMARK 500 11 LEU A 47 116.32 -10.85
REMARK 500 11 ARG A 48 62.38 -160.57
REMARK 500 11 GLU A 51 -50.81 -167.87
REMARK 500 12 CYS A 6 94.74 -174.80
REMARK 500 12 TYR A 13 20.68 47.15
REMARK 500 12 ASN A 16 -53.34 76.78
REMARK 500 12 SER A 25 -30.20 88.70
REMARK 500 12 LEU A 26 17.48 -150.46
REMARK 500 12 ASP A 40 117.83 -33.56
REMARK 500 12 ARG A 41 16.06 85.85
REMARK 500 12 THR A 44 89.62 -69.49
REMARK 500 12 ARG A 48 50.92 94.04
REMARK 500 12 GLU A 51 -55.93 -164.11
REMARK 500 13 CYS A 6 111.02 176.05
REMARK 500 13 SER A 8 -6.17 95.05
REMARK 500 13 TYR A 10 -89.08 -85.38
REMARK 500 13 ASP A 11 89.71 157.33
REMARK 500 13 ASN A 16 -54.15 82.11
REMARK 500 13 LEU A 26 26.18 -161.86
REMARK 500 13 CYS A 33 -147.24 -61.13
REMARK 500 13 ARG A 41 -82.52 -128.40
REMARK 500 13 CYS A 42 26.99 172.15
REMARK 500 13 ASP A 46 -145.58 -64.19
REMARK 500 13 LEU A 47 -51.06 -121.82
REMARK 500 13 ARG A 48 74.15 174.16
REMARK 500 13 TRP A 49 47.22 -88.44
REMARK 500 14 CYS A 6 82.99 -177.07
REMARK 500 14 ASP A 11 55.58 -113.77
REMARK 500 14 ASN A 16 23.05 48.16
REMARK 500 14 LEU A 26 31.98 -164.04
REMARK 500 14 ASP A 27 28.88 46.10
REMARK 500 14 CYS A 33 -135.36 -75.12
REMARK 500 14 SER A 38 -154.23 -164.78
REMARK 500 14 ASP A 40 108.14 -177.74
REMARK 500 14 CYS A 42 69.82 68.32
REMARK 500 14 THR A 44 72.87 -65.72
REMARK 500 14 ASP A 46 -143.64 -71.20
REMARK 500 14 ARG A 48 68.08 75.78
REMARK 500 15 CYS A 6 89.33 157.43
REMARK 500 15 SER A 8 15.25 47.39
REMARK 500 15 SER A 9 22.87 46.86
REMARK 500 15 TYR A 10 38.36 31.39
REMARK 500 15 ASP A 11 74.29 61.98
REMARK 500 15 ASP A 27 24.47 44.18
REMARK 500 15 CYS A 31 118.89 -162.56
REMARK 500 15 CYS A 33 -147.47 -67.01
REMARK 500 15 SER A 38 -168.79 -161.27
REMARK 500 15 ASP A 40 48.67 38.09
REMARK 500 15 ARG A 41 -30.37 174.60
REMARK 500 15 CYS A 42 20.33 83.70
REMARK 500 15 LEU A 47 81.07 38.28
REMARK 500 15 ARG A 48 31.54 -164.49
REMARK 500 15 TRP A 50 -50.31 -139.76
REMARK 500 16 CYS A 6 95.94 -174.78
REMARK 500 16 ASP A 11 72.66 53.67
REMARK 500 16 SER A 25 -29.59 88.28
REMARK 500 16 LEU A 26 17.99 -151.30
REMARK 500 16 CYS A 33 -159.43 -119.38
REMARK 500 16 ILE A 35 138.59 -34.47
REMARK 500 16 ASP A 40 -32.65 -36.35
REMARK 500 16 CYS A 42 38.74 153.43
REMARK 500 16 ASP A 46 -34.31 -32.99
REMARK 500 16 LEU A 47 60.51 -65.96
REMARK 500 16 ARG A 48 82.31 164.75
REMARK 500 16 TRP A 49 -168.90 -55.21
REMARK 500 16 TRP A 50 -67.16 -158.49
REMARK 500 16 GLU A 51 -97.83 -155.06
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: PLANAR GROUPS
REMARK 500
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS
REMARK 500 AN RMSD GREATER THAN THIS VALUE
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 M RES CSSEQI RMS TYPE
REMARK 500 1 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 1 ARG A 45 0.28 SIDE_CHAIN
REMARK 500 1 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 1 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 2 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 2 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 2 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 2 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 3 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 3 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 3 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 3 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 4 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 4 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 4 ARG A 48 0.29 SIDE_CHAIN
REMARK 500 4 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 5 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 5 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 5 ARG A 48 0.29 SIDE_CHAIN
REMARK 500 5 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 6 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 6 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 6 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 6 ARG A 53 0.29 SIDE_CHAIN
REMARK 500 7 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 7 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 7 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 7 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 8 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 8 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 8 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 8 ARG A 53 0.26 SIDE_CHAIN
REMARK 500 9 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 9 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 9 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 9 ARG A 53 0.29 SIDE_CHAIN
REMARK 500 10 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 10 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 10 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 10 ARG A 53 0.27 SIDE_CHAIN
REMARK 500 11 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 11 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 11 ARG A 48 0.28 SIDE_CHAIN
REMARK 500 11 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 12 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 12 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 12 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 12 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 13 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 13 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 13 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 13 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 14 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 14 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 14 ARG A 48 0.28 SIDE_CHAIN
REMARK 500 14 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 15 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 15 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 15 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 15 ARG A 53 0.30 SIDE_CHAIN
REMARK 500 16 ARG A 41 0.30 SIDE_CHAIN
REMARK 500 16 ARG A 45 0.30 SIDE_CHAIN
REMARK 500 16 ARG A 48 0.30 SIDE_CHAIN
REMARK 500 16 ARG A 53 0.17 SIDE_CHAIN
REMARK 500
REMARK 500 REMARK: NULL
DBREF 1EGF A 1 53 UNP P01132 EGF_MOUSE 977 1029
SEQRES 1 A 53 ASN SER TYR PRO GLY CYS PRO SER SER TYR ASP GLY TYR
SEQRES 2 A 53 CYS LEU ASN GLY GLY VAL CYS MET HIS ILE GLU SER LEU
SEQRES 3 A 53 ASP SER TYR THR CYS ASN CYS VAL ILE GLY TYR SER GLY
SEQRES 4 A 53 ASP ARG CYS GLN THR ARG ASP LEU ARG TRP TRP GLU LEU
SEQRES 5 A 53 ARG
SHEET 1 A 3 SER A 2 TYR A 3 0
SHEET 2 A 3 VAL A 19 ILE A 23 -1 O HIS A 22 N TYR A 3
SHEET 3 A 3 TYR A 29 ASN A 32 -1 N THR A 30 O MET A 21
SSBOND 1 CYS A 6 CYS A 20 1555 1555 1.92
SSBOND 2 CYS A 14 CYS A 31 1555 1555 1.53
SSBOND 3 CYS A 33 CYS A 42 1555 1555 1.86
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
MODEL 1
(ATOM LINES ARE NOT SHOWN.)
END
